个人简历

2020.04-至今：中国农业大学，优秀人才引进，副教授
2016.06-2020.04：中国农业大学食品营养与人类健康高精尖创新中心，岗位科学家
2014.10-2016.06：浙江大学转化医学研究院/浙一医院，助理研究员
2009.09-2014.06：中国科学院上海生命科学研究院营养科学研究所/华东理工大学，联合培养博士
2009.09-2011.09：中国科学院上海生命科学研究院营养科学研究所，硕士
2005.09-2009.06：武汉大学生命科学学院，学士

研究领域

1. 铁代谢疾病发病机制和遗传学研究
2. 铁代谢疾病诊治标志物研究
3. 铁代谢疾病干预策略研究""

近期论文

1. An, P.#, Wang, J.#, Wang, H., Jiang, L., Wang, J., Min, J. & Wang, F. (2020) Gnpat does not play an essential role in systemic iron homeostasis in murine model. Journal of Cellular and Molecular Medicine. (# Co-first author)
2. An, P.#, Wang, H.#, Wu, Q., Wang, J., Xia, Z., He, X., Wang, X., Chen, Y., Min, J. & Wang, F. (2018) Smad7 deficiency decreases iron and haemoglobin through hepcidin up-regulation by multilayer compensatory mechanisms. Journal of Cellular and Molecular Medicine, 22, 3035–3044. (# Co-first author)
3. An, P.#, Jiang, L.#, Guan, Y., Wang, H., Wang, J., Tian, Y., Yang, W., Shi, Y., Xue, J., Min, J. & Wang, F. (2017) Identification of hereditary hemochromatosis pedigrees and a novel SLC40A1 mutation in Chinese population. Blood cells, molecules & diseases, 63, 34–36. (# Co-first author)
4. An, P., Wang, H., Wu, Q., Guo, X., Wu, A., Zhang, Z., Zhang, D., Xu, X., Mao, Q., Shen, X., Zhang, L., Xiong, Z., He, L., Liu, Y., Min, J., Zhou, D. & Wang, F. (2015) Elevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk. Scientific Reports, 5, 13106.
5. An, P., Wu, Q., Wang, H., Guan, Y., Mu, M., Liao, Y., Zhou, D., Song, P., Wang, C., Meng, L., Man, Q., Li, L., Zhang, J. & Wang, F. (2012) TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia. Human Molecular Genetics, 21, 2124–2131.
6. Guan, Y.#, An, P.#, Zhang, Z., Zhang, F., Yu, Y., Wu, Q., Shi, Y., Guo, X., Tao, Y. & Wang, F. (2013) Screening identifies the Chinese medicinal plant Caulis Spatholobi as an effective HAMP expression inhibitor. Journal of Nutrition, 143, 1061–1066. (# Co-first author)
7. Guo, X.#, Zhou, D.#, An, P.#, Wu, Q., Wang, H., Wu, A., Mu, M., Zhang, D., Zhang, Z., Wang, H., He, L., Liu, Y. & Wang, F. (2013b) Associations between serum hepcidin, ferritin and Hb concentrations and type 2 diabetes risks in a Han Chinese population. The British Journal of Nutrition, 110, 2180–2185. (# Co-first author)
8. Wang, X.#, An, P.#, Zeng, J., Liu, X., Wang, B., Fang, X., Wang, F., Ren, G. & Min, J. (2017b) Serum ferritin in combination with prostate-specific antigen improves predictive accuracy for prostate cancer. Oncotarget, 8, 17862–17872. (# Co-first author)
9. Wang, H., An, P., Xie, E., Wu, Q., Fang, X., Gao, H., Zhang, Z., Li, Y., Wang, X., Zhang, J., Li, G., Yang, L., Liu, W., Min, J. & Wang, F. (2017a) Characterization of ferroptosis in murine models of hemochromatosis. Hepatology, 66, 449–465.
10. Mu, M., An, P., Wu, Q., Shen, X., Shao, D., Wang, H., Zhang, Y., Zhang, S., Yao, H., Min, J. & Wang, F. (2016) The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression. The Journal of Nutritional Biochemistry, 30, 53–61.
11. Fang, X., An, P., Wang, H., Wang, X., Shen, X., Li, X., Min, J., Liu, S. & Wang, F. (2014) Dietary intake of heme iron and risk of cardiovascular disease: A dose-response meta-analysis of prospective cohort studies. Nutrition, Metabolism and Cardiovascular Diseases, 25, 24–35.
12. Fang, X., Wang, H., An, P., Min, J. & Wang, F. (2015a) Cardiomyocyte-specific deletion of ferroportin using MCK-Cre has no apparent effect on cardiac iron homeostasis. International Journal of Cardiology, 201, 90–92.
13. Fang, X., Wei, J., He, X., An, P., Wang, H., Jiang, L., Shao, D., Liang, H., Li, Y., Wang, F. & Min, J. (2015b) Landscape of dietary factors associated with risk of gastric cancer: A systematic review and dose-response meta-analysis of prospective cohort studies. European Journal of Cancer, 51, 2820–2832.
14. Gan, W., Guan, Y., Wu, Q., An, P., Zhu, J., Lu, L., Jing, L., Yu, Y., Ruan, S., Xie, D., Makrides, M., Gibson, R.A., Anderson, G.J., Li, H., Lin, X. & Wang, F. (2012) Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population. The American Journal of Clinical Nutrition, 95, 626–632.
15. Huang, T., Lan, L., Fang, X., An, P., Min, J. & Wang, F. (2015) Promises and Challenges of Big Data Computing in Health Sciences. Big Data Research, 2, 2–11.
16. Jiang, Y., Li, C., Wu, Q., An, P., Huang, L., Wang, J., Chen, C., Chen, X., Zhang, F., Ma, L., Liu, S., He, H., Xie, S., Sun, Y., Liu, H., Zhan, Y., Tao, Y., Liu, Z., Sun, X., Hu, Y., et al (2019b) Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses. Nature Communications, 10, 2935.
17. Mu, M., Wu, A., An, P., Du, X., Wu, Q., Shen, X. & Wang, F. (2014) Black soyabean seed coat extract regulates iron metabolism by inhibiting the expression of hepcidin. The British Journal of Nutrition, 111, 1181–1189.
18. Wu, Q., Wang, H., An, P., Tao, Y., Deng, J., Zhang, Z., Shen, Y., Chen, C., Min, J. & Wang, F. (2015) HJV and HFE Play Distinct Roles in Regulating Hepcidin. Antioxidants & redox signaling, 22, 1325–1336.
19. Zhang, F., Tao, Y., Zhang, Z., Guo, X., An, P., Shen, Y., Wu, Q., Yu, Y. & Wang, F. (2012a) Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses. Haematologica, 97, 1826–1835.
20. Zhang, Z., Zhang, F., An, P., Guo, X., Shen, Y., Tao, Y., Wu, Q., Zhang, Y., Yu, Y., Ning, B., Nie, G., Knutson, M.D., Anderson, G.J. & Wang, F. (2011) Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood, 118, 1912–1922.
21. Zhang, Z., Zhang, F., Guo, X., An, P., Tao, Y. & Wang, F. (2012b) Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice. Hepatology, 56, 961–971.