个人简历

李洋，博士，中国科学院深圳先进技术研究院，医药所，研究员，博士生导师，炎症与疫苗研究室副主任，免疫学和纳米医学课题组组长。曾获欧盟玛丽居里基金资助，于奥地利萨尔斯堡大学博士毕业。先后于欧洲意大利国家科学院、美国堪萨斯纳米技术研发中心及科罗拉多大学从事纳米免疫学，癌症免疫学方面的研究。2018年7月正式回国于中国科学院深圳先进技术研究院，组建免疫学和纳米医学实验室。主持2项（NanoTOES，QualityNano-TA）并参与多项欧盟FP7研究计划，主持国家自然科学基金项目青年、面上项目及国际合作项目，主持广东省杰出青年项目，科学院国际合作项目，参与美国R01研究计划等。在以通讯作者及第一作者，在包括Nature Nanotechnology（2021共同通讯，2022末位通讯）, Biomaterials，ACS Applied Materials & Interfaces等在内的国际知名期刊上发表多篇论文；共发表40多篇，ESI高被引论文2篇；曾获河北省自然科学一等奖，国家自费留学生奖学金等奖励。意大利免疫学和临床免疫学学会、中国生物物理学会和中国毒理学会会员，ACS Nano，Advanced Science，Small，Science Advances等杂志的审稿人。

研究领域

"""""1） 癌症免疫学（肿瘤免疫治疗） \r
2） 纳米医学（纳米药物的肿瘤靶向与免疫治疗） \r
3） 免疫学（巨噬细胞，IL-1家族，炎症因子） \r
4） 纳米免疫安全性 （纳米毒理学）\r
"

近期论文

A Nanomaterial Targeting the Spike Protein Captures SARS-CoV-2 Variants and Promotes Viral Elimination. Guofang Zhang#, Yalin Cong#, Feng-Liang Liu#, Jiufeng Sun#, Jiantian Zhang, Guoli Cao, Lingqiang Zhou, Wenjie Yang, Qingle Song, Fangjun Wang, Ke Liu, Jing Qu, Jing Wang, Min He, Shun Feng, Didar Baimanov, Wei Xu, Rong-Hua Luo, Xin-Yan Long, Shumin Liao, Yunping Fan, Yu-Feng Li, Bai Li, Ximing Shao, Guocheng Wang, Lijing Fang, Huaiyu Wang, Xue-Feng Yu, Yan-Zhong Chang, Yuliang Zhao, Liang Li, Peng Yu, Yong-Tang Zheng*, Diana Boraschi, Hongchang Li*, Chunying Chen*, Liming Wang*, Yang Li*. Nature Nanotechnology, 2022, 17 (9), 993-1003. \r
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Intrinsic Bioactivity of Black Phosphorus Nanomaterials on Mitotic Centrosome Destabilization through Suppression of PLK1 Kinase. Ximing Shao, Zhihao Ding, Wenhua Zhou, Yanyan Li, Zhibin Li, Haodong Cui, Xian Lin, Guoli Cao, Binghua Cheng, Haiyan Sun, Meiqing Li, Ke Liu, Danyi Lu, Shengyong Geng, Wenli Shi, Guofang Zhang, Qingle Song, Liang Chen, Guocheng Wang, Wu Su, Lintao Cai, Lijing Fang, David Tai Leong, Yang Li*, Xue-Feng Yu* & Hongchang Li*. Nature Nanotechnology, 2021, 16, 1150–1160. \r
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Microplastics Interact with SARS-CoV-2 and Facilitate Host Cell Infection. Guofang Zhang, Guoli Cao, Rong-Hua Luo, Qingle Song, Yanqiao Zeng, Ke Liu, Jing Qu, Xian Lin, Feng-Liang Liu, Guocheng Wang, Hongchang Li, Liang Li, Yong-Tang Zheng, Diana Boraschi, Lidong Wu, Yan-Zhong Chang, Yang Li*. Environmental Science: Nano, 2022, 9: 2653-2664. \r
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The Importance of IL-1 Family Cytokines in Nanoimmunosafety and Nanotoxicology. Guofang Zhang, Wenhe Luo, Wenjie Yang, Su Li, Dongjie Li, Yanqiao Zhang, Yang Li*. WIREs: Nanomedicine and Nanobiotechnology, 2022, 14(6):e1850. \r
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Reinforce the Combinational Immuno-Oncotherapy of Switching “Cold” Tumor to “Hot” by Responsive Penetrating Nanogels. Qingle Song, Guofang Zhang, Bo Wang, Guoli Cao, Dongjie Li, Yu Wang, Yuqian Zhang, Jin Geng, Hongchang Li and Yang Li*. ACS Applied Materials & Interfaces, 2021, 13(31): 36824-36838. \r
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The Synergistic Strategies for the Immuno-oncotherapy with Photothermal Nanoagents. Yuqian Zhang, Guofang Zhang, Guocheng Wang, Lidong Wu, Nancy A Monteiro-Riviere, Yang Li*, WIREs: Nanomedicine and Nanobiotechnology, 2021, e1717. \r
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Applications of Magnetite-Nanoparticles in Cancer Immunotherapies: Present Hallmarks and Future Perspectives. Qingle Song, Amaneh Javid, Guofang Zhang, Yang Li*. Frontiers in Immunology, 2021, 12: 701485. \r
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Editorial: Immunological Effects of Nano-Imaging Materials. Yang Li*, Pengfei Zhang, Ben-Zhong Tang, Diana Boraschi*. Frontiers in Immunology, 2022, 13: 886415. \r
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The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways. Yang Li, Ying Liu, Yujian Fu, Taotao Wei, Laurent Le Guyader, Ge Gao, Ru-Shi Liu, Yanzhong Chang*, Chunying Chen*. Biomaterials, 2012, 33(2), 402-411. \r
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Assessing the immunosafety of engineered nanoparticles with a novel in vitro model based on human primary monocytes. Yang Li*, Paola Italiani, Eudald Casals, Dirk Valkenborg, Inge Mertens, Geert Baggerman, Inge Nelissen, Victor F. Puntes, Diana Boraschi. ACS Applied Materials & Interfaces, 2016, 8(42): 28437–28447. \r