个人简历

南京大学生物化学学士(1996年)、博士(2000年)，加州大学圣巴巴拉分校(UCSB)有机固体研究所和加州纳米系统研究所博士后(导师：2000年诺贝尔化学奖得主Alan J. Heeger教授)。2004年1月起任中国科学院上海应用物理研究所研究员。现任物理生物学研究室和上海光源国家科学中心（筹）生物成像中心主任，中国科学院特聘研究员。2007年获得国家杰出青年基金，2012年任科技部重大科学研究计划（纳米）首席科学家。兼任亚利桑那州立大学(Arizona State University)生物设计研究院客座教授，美国化学会ACS Applied Materials & Interfaces副主编，Advanced Healthcare Materials, ACS Sensors, ChemBioChem, ChemPlusChem, Journal of Materials Chemistry, Electroanalysis, Particle, 中国科学-化学，化学学报，化学进展，分析化学等杂志编委。

研究领域

"""""主要研究方向为生物传感与成像、DNA纳米技术与DNA计算和生物光子学。"

近期论文

X. Liu, F. Zhang, X. Jing, M. Pan, P. Liu, W. Li, B. Zhu, J. Li, H. Chen, L. Wang, J. Lin, Y. Liu, d. Zhao, H. Yan*, C. Fan*, Complex silica composite nanomaterials templated with DNA origami. Nature 559, 593 (2018).\r
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J. Li, A. A. Green*, H. Yan*, C. Fan*, Engineering nucleic acid structures for programmable Molecular circuitry and intracellular biocomputation. Nature Chem. 9, 1056 (2017).\r
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H. Zhang, J. Chao*, D. Pan, H. Liu, Y. Qiang, K. Liu, C. Cui, J. Chen, Q. Huang, J. Hu, L.Wang, W. Huang, Y. Shi* and C. Fan*, DNA origami-based shape IDs for single-molecule nanomechanical genotyping. Nature Commun. 8, 28341 (2017).\r
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M. Liu, Q. Li, L. Liang, J. Li, K. Wang, J. Li, M. Lv, N. Chen, H. Song, J. Lee, J. Shi, L.Wang, R. Lal*, C. Fan*, Realtime visualization of clustering and intracellular transport of gold nanoparticles by correlative imaging. Nature Commun. 8, 15646 (2017).\r
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X. Qu, D. Zhu, G. Yao, S. Su, J. Chao, H. Liu, X. Zuo, L. Wang, J. Shi, L. Wang, W. Huang,H. Pei*, C. Fan*, An Exonuclease III-Powered on-particle Stochastic DNA Walker. Angew.Chem. Int. Ed. 56, 1855 (2017).\r
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Y. Zhang, Z. Cui, H. Kong, K. Xia, L. Pan, J. Li, Y. Sun, J. Shi, L. Wang, Y. Zhu* and C.Fan*, One-shot immunomodulatory nanodiamond agents for cancer immunotherapy. Adv. Mater. 28, 2699 (2016).\r
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H. Liu, J. Wang, S. Song, C. Fan* and K. V. Gothelf*, A DNA-based system for selecting and displaying the combined result of two input variable. Nature Commun. 6, 10089 (2015).\r
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M. Lin, J. Wang, G. Zhou, J. Wang, N. Wu, J. Lu, J. Gao, X. Chen, J. Shi, X. Zuo*, C. Fan*,Programmable engineering of biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection. Angew. Chem. Int. Ed. 54, 2151 (2015).\r
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G. Yao, J. Li, J. Chao, H. Pei, H. J. Liu, Y. Zhao, J. Y. Shi, Q. Huang, L. H. Wang, W. Huang And C. Fan*, Gold-Nanoparticle-Mediated Jigsaw-Puzzle-like Assembly of Supersized Plasmonic DNA Origami. Angew. Chem. Int. Ed. 54, 2966 (2015).\r
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L. Liang, J. Li, Q. Li, Q. Huang*, J. Y. Shi, H. Yan and C. Fan*, Single-Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells. Angew.Chem. Int. Ed. 53, 7745 (2014).\r
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F. Yang, X. L. Zuo, Z. H. Li, W. P. Deng, J. Y. Shi, G. J. Zhang, Q. Huang, S. P. Song and C.Fan*, A Bubble-Mediated Intelligent Microscale Electrochemical Device for Single-Step Quantitative Bioassays. Adv. Mater. 26, 4671 (2014).\r
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Y. Fu, D. Zeng, J. Chao, Y. Q. Jin, Z. Zhang, H. Liu*, D. Li, H. W. Ma, Q. Huang, K. V.Gothelf and C. Fan*, Single-Step Rapid Assembly of DNA Origami Nanostructures for Addressable Nanoscale Bioreactors. J. Am. Chem. Soc. 135, 696 (2013).\r
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H. Pei, L. Liang, G. B. Yao, J. Li, Q. Huang and C. Fan*, Reconfigurable Three-Dimensional dNA Nanostructures for the Construction of Intracellular Logic Sensors. Angew. Chem. Int.Ed. 51, 9020 (2012).\r
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H. Pei, F. Li, Y. Wan, M. Wei, H. Liu*, Y. Su, N. Chen, Q. Huang and C. Fan*, Designed diblock Oligonucleotide for the Synthesis of Spatially Isolated and Highly Hybridizable Functionalization of DNA-Gold Nanoparticle Nanoconjugates. J. Am. Chem. Soc. 134, 11876(2012). \r
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N. Lu, H. Pei, Z. L. Ge, C. R. Simmons, H. Yan* and C. Fan*, Charge Transport within a Three-Dimensional DNA Nanostructure Framework. J. Am. Chem. Soc. 134, 13148 (2012).\r
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P. Chen, D. Pan, C. Fan*, J. Chen, K. Huang, D. F. Wang, H. L. Zhang, Y. Li, G. Y. Feng, P. J. Liang, L. He and Y. Shi*, Gold nanoparticles for high-throughput genotyping of long-range haplotypes. Nature Nanotechnol. 6, 639 (2011).\r
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H. Pei, N. Lu, Y. L. Wen, S. P. Song, Y. Liu, H. Yan* and C. Fan*, A DNA nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing. Adv. Mater. 22, 4754 (2010).\r
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S. Song, Z. Liang, J. Zhang, L. Wang, G. Li* and C. Fan*, Gold-Nanoparticle-Based Multicolor Nanobeacons for Sequence-Specific DNA Analysis. Angew. Chem. Int. Ed. 48,8670 (2009).\r
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G. Liu, Y. Wan, V. Gau, J. Zhang, L. Wang, S. Song and C. Fan*, An enzyme-based E-DNA sensor for sequence-specific detection of femtomolar DNA targets. J. Am. Chem. Soc. 130,6820 (2008).\r
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J. Zhang, S. Song, L. Zhang, L. Wang, H. Wu, D. Pan and C. Fan*, Sequence-specific detection of femtomolar DNA via a chronocouloumetric DNA sensor (CDS): Effects of nanoparticle-mediated amplification and nanoscale control of DNA assembly at electrodes. J. Am. Chem. Soc., 128, 8575 (2006)