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郭跃伟
2023-05-17 11:05
  • 郭跃伟
  • 郭跃伟 - 研究员--郭跃伟-个人资料

近期热点

资料介绍

个人简历


教育经历
07/01/1978 - 07/01/1982 北京中医药大学中药学院,学士
07/01/1985 - 07/01/1988 中国药科大学/南京药物研究所,硕士
01/01/1994/ - 09/01/1997 意大利那不勒斯大学药学院/意大利国家科学院生物活性分子化学研究所,博士
10/01/1997 - 02/01/2000 意科院生物活性分子化学研究所,博士后
06/01/2000 - 02/01/2001 日本北海道大学药学院,研究员
工作经历
07/01/1982 – 07/01/1985 山西医科大学药学系,助教
09/01/1988 – 12/01/1993 南京药物研究所,助研
01/01/1994 – 02/01/2000 意科院生物活性分子化学研究所/意大利那不勒斯大学药学院,访问学者、博士、博士后
02/01/2000 – 07/01/2000 中科院上海药物研究所,研究员
06/01/2000 – 02/01/2001 日本北海道大学药学院,研究员
02/01/2000 - 至今 中科院上海药物研究所(2级研究员),所学位委员会副主任,上海药物所烟台分所副所长

研究领域


1.海洋生物和药用植物中生物活性成分的化学研究
2.海洋后鳃亚纲软体生物及其食源生物的化学及化学生态学研究

近期论文


1. Jiang CS, Mueller W, Schroder C, Guo YW*. Disulfide- and multisulfide-containing metabolites from marine organisms. Chem Rev 2012; 112: 2179-2207.
2. Cai YS, Guo YW*, Khron K. Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes. Nat Prod Rep 2010; 27: 1840-1870.
3. Liang LF, Kurtán T, Mándi A, Yao LG, Li J, Zhang W, Guo YW*. Unprecedented diterpenoids as a PTP1B inhibitor from Hainan soft coral Sarcophyton trocheliophorum Marenzeller. Org Lett 2013; 15: 274-277.
4. Chen XL, Liu HL, Li J, Xin GR, Guo YW*. Paracaseolide A, first r-alkylbutenolide dimer with an unusual tetraquinane oxa-cage bislactone skeleton from Chinese mangrove Sonneratia paracaseolaris. Org Lett 2011; 13: 5032-5035.
5. Manzo E, Carbone M, Mollo E, Irace C, Di Pascale A, Li Y, Ciavatta ML, Cimino G, Guo YW*, Gavagnin M*. Structure and synthesis of a unique isonitrile lipid isolated from the marine mollusk Actinocyclus papillatus. Org Lett 2011; 13: 1897-1899.
6. Carbone M, Li Y, Irace C, Mollo E, Castelluccio F, Di Pascale A, Cimino G, Santamaria R, Guo YW*, Gavagnin M*. Structrue and cytotoxicity of phidianidines A and B: first finding of 1,2,4-oxadiazole system in a marine natural product. Org Lett 2011; 13: 2516-2519.
7. Jia R, Yan XH, Zhang W, Guo YW*. Bislatumlides C-F, further biscembranes from the Hainan soft coral Sarcophyton latum. J Org Chem 2013; 78: 3113-3119.
8. Cai YS, Kurtán T, Miao ZH, Mándi A, Komáromi I, Liu HL, Ding J, Guo YW*. Palmarumycins BG1–BG7 and preussomerin BG1, and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra. J Org Chem 2011; 76: 1821-1828.
9. Wang JR, Liu HL, Kurtán T, Mándi A, Antus S, Li J, Zhang HY, Guo YW*. Protolimonoids and norlimonoids from the stem bark of Toona ciliata var. pubescens. Org Biomol Chem 2011; 9: 7685-7696.
10. Wang JR, Carbone M, Gavagnin M, Mándi A, Antus S, Yao LG, Cimino G, Kurtán T, Guo YW*. Assignment of absolute configuration of bis--pyrone polypropionates from marine pulmonate molluscs. Eur J Org Chem 2012; 1107-1111.
11. Wang JR, Kurtán T, Mándi A, Guo YW*. Structures and absolute stereochemistries of nortriterpenoids from Schisandra chinensis (Turcz.) Baill. Eur J Org Chem 2012; 5471-5482.
12. Kurtán T, Jia R, Li Y, Pescitelli G, Guo YW*. Absolute configuration of highly flexible natural products by the solid-state ECD/TDDFT method: ximaolides and sinulaparvalides. Eur J Org Chem 2012; 6722-6728.
13. Carbone M, Ciavatta ML, Wang JR, Cirillo I, Mathieu V, Kiss R, Mollo E, Guo YW*, Gavagnin M*. Extending the record of bis-γ-pyrone polypropionates from marine pulmonate mollusks. J Nat Prod 2013; 76: 2065-2073.
14. Huang XY, Wang Q, Liu HL, Zhang Y, Xin GR, Shen X, Dong ML, Guo YW*. New diastereoisomeric macrocyclic polydisulfides from the mangrove Bruguiera gymnorrhiza. Phytochemistry 2009; 70: 2096-2100.
国际刊物“Marine Drugs”,“The Open Organic Chemistry Journal”,“Natural Product Science”,“Frontiers in Pharcology of Natural Products”和国内刊物“药学学报”,“中国天然药物”,“中国中药杂志”,“天然产物研究与开发”,“国际药学研究杂志”,“应用与环境生物学报”编委;中国药学会海洋药物专业委员会副主任委员;中科院南海海洋所、上海交通大学、合肥工业大学、江苏科技大学、山西大学客座教授。

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