个人简历

教育经历\r
2005. 9-2009. 6，武汉大学，药学，理学学士\r
2014. 2-2015. 6，斯坦福大学，分子影像中心，联合培养博士\r
2009 .9-2015. 6，武汉大学，生物化学与分子生物学（药物化学方向），理学博士\r
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工作经历\r
2015. 6-2019. 2 斯坦福大学，分子影像中心，博士后\r
2019. 2-至今 中国科学院上海药物研究所，研究员，课题组长

研究领域

""1. 有机小分子诊疗药物研发 (荧光，PET-CT/SPECT-CT等，药物化学)\r
2. 分子影像技术在药物开发中的应用研究（药理学）\r
3. 短波红外或近红外二区新型成像系统，软件算法开发（仪器设备）""""

近期论文

A. Ji#, H. Lou#, C. Qu, W. Lu, Y. Hao, J. Li, Y. Wu, T. Chang, H. Chen*, Z. Cheng*. Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance. Nature Communications, 2022 (accepted)\r
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H. Chen#, L. Liu#, K. Qian, H. Liu, Z. Wang, F. Gao, C. Qu, W. Dai, D. Lin, K. Chen, H. Liu*, Z. Cheng*. Bioinspired Large Stokes Shift Small Molecular Dyes for Biomedical Fluorescent Imaging. Science Advances, 2022 (accepted)\r
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Q. Qiu, T. Chang, Y. Wu, C. Qu*, H. Chen*, Z. Chen*. Liver injury long-term monitoring and fluorescent image-guided tumor surgery using self-assembly amphiphilic donor-acceptor NIR-II dye. Biosensors and Bioelectronics, 2022. doi: https://doi.org/10.1016/j.bios.2022.114371\r
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L. Zheng#, Z. Wang#, X. Zhang, Y. Zhou, A. Ji, H. Lou, X. Liu*, H. Chen*, Z. Cheng*. Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging. Journal of Medicinal Chemistry, 2022, 65(1), 497-506. (封面文章)\r
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Y. Li#, H. Zhou#, R. Bi, X. Li, Y. Yang, J. Ni, W. H. Liew, M. Olivo, K. Yao, J. Liu*, H. Chen*, K. Li*. Acceptor Engineering of Small Molecule Fluorophores for NIR-II Fluorescent and Photoacoustic Imaging. Journal of Materials Chemistry B, 2021, 9 (48), 9951-9960. \r
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X. Zhang#, A. Ji#, Z. Wang, H. Lou, J. Li, L. Zheng, Y. Zhou, C. Qu*, X. Liu*, H. Chen*, Z. Cheng*. Azide-dye unexpected bone targeting for near-infrared window II osteoporosis imaging. Journal of Medicinal Chemistry, 2021, 64, 11543-11553. (封面文章)\r
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H. Chen#, H. Yang#, C. Zhang, S. Chen, X. Zhao, M. Zhu, Z. Wang, Y. Wang, H. T. Wo, K. Li*, Z. Cheng*. Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker. Research, 2021, 9798580.\r
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H. Chen, K. Shou, S. Chen, C. Qu, Z. Wang, L. Jiang, M. Zhu, B. Ding, K. Qian, A. Ji, H. Lou, L. Tong, A. Hsu, Y. Wang, D. W. Felsher, Z. Hu*, J. Tian*, Z. Cheng*. Smart Self‐Assembly Amphiphilic Cyclopeptide‐Dye for Near‐Infrared Window‐II Imaging. Advanced Materials, 2021, 2006902. （封面文章）\r
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Y. Yang, X. Fan, L. Li, Y. Yang, A. Nuernisha, D. Xue, C. He, J. Qian*, Q. Hu*, H. Chen*, J. Liu*, W. Huang. Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence. ACS Nano, 2020, 14 (2), 2509–2521. （高被引文章）\r
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H. Chen#, J. Wang#, X. Feng, H, M. Zhu, S. Hoffmann, A. Hsu, K. Qian, D. Huang, F. Zhao, W. Liu, H. Zhang*, Z. Cheng*. Mitochondria-targeted fluorescent molecules for high efficiency cancer growth inhibition and imaging. Chemical Science, 2019, 10, 7946-7951.