个人简历

1998年毕业于四川大学应用化学系；2003年获中科院上海有机化学研究所理学博士学位；之后在美国伊利诺伊大学香槟分校（University of Illinois at Urbana-Champaign, UIUC）化学系Wilfred A. van der Donk课题组从事博士后及研究助理，研究领域为化学生物学；2008年5月任上海有机化学研究所创新岗位副研究员，课题组长，研究生导师；2012年1月起任研究员，2020年4月起任中科院有机氟化学重点实验室主任，2020年4月起任国际期刊Org. Chem. Front顾问编委。2009年入选上海市启明星计划。荣获2014年国家杰出青年科学基金，Thieme Chemistry Journal Award 2014，2015年第五届中国化学会—英国皇家化学会青年化学奖, 2015年英国皇家化学会氟化学奖（RSC Fluorine Chemistry Prize 2015)，2021年“中国化学会黄维垣氟化学奖”。

研究领域

"""""含氟有机化合物由于其独特性，在医药、农药、材料等与人口健康、国民生活和国防建设紧密相关的领域中具有重要的应用。本课题组围绕有机氟化学领域，针对目前有机氟化学存在的重要科学问题，以过渡金属催化为手段，从新反应性、新成键模式和新功能的理念出发，通过新催化体系的建立和含氟试剂新特性的发现，发展高效安全、环境友好、原子/步骤经济、可控构筑与转化含氟有机化合物的方法和理论，解决其中有机氟化学存在的重要科学问题，进而利用所发展方法合成特种含氟功能材料和具有生物活性的含氟分子\r
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（1）金属有机氟化学，包括金属二氟卡宾化学和廉价含氟资源导向的过渡金属催化的有机氟化学新反应和新策略的发展\r
（2）基于有机氟化学与化学生物相关的研究"

近期论文

3,3-Difluoroallyl Sulfonium Salts: Practical and Bench-StableReagents for Highly Regioselective gem-Difluoroallylations Xiao-Tian Feng, Jin-Xiu Ren, Xing Gao, Qiao-Qiao Min, and Xingang Zhang* Angew. Chem. Int. Ed. 2022, e202210103.DOI: 10.1002/anie.202210103.\r
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Nickel-catalyzed alkyl-arylation of 3,3,3-trifluoropropene Chang Xu, Ming-Kuan Wang, Shu Zhang & Xingang Zhang* Commun. Chem. 2022, 5, 41.DOI: 10.1038/s42004-022-00659-7.\r
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Coupling of Heteroaryl Halides with Chlorodifluoroacetamides and Chlorodifluoroacetate via Nickel Catalysis Dawei Zhang, Xing Gao, Qiao-Qiao Min, Yucheng Gu, Guillaume Berthon, and Xingang Zhang* Chem. Eur. J. 2022, 28, e202200642 DOI: 10.1002/chem.202200642\r
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(Fluoro)alkylation of Alkenes Promoted by Photolysis of Alkylzirconocenes Xiaoxiao Ren, Xing Gao, Qiao-Qiao Min, Shu Zhang, and Xingang Zhang*Chem. Sci. 2022, 13, 3454-3460.\r
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Palladium-Catalyzed Carbonylative Cross-Coupling of Difluoroalkyl Halides with Alkylboranes under 1 atm of CO Hai-Yang Zhao,§ Minqi Zhou,§ and Xingang Zhang* Org. Lett. 2021, 23, 23, 9106-9111.\r
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Regio- and enantioselective umpolung gemdifluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand Shuai Huang, Fei-Fei Tong, Da-Chang Bai, Gao-Peng Zhang, Yang-Jie Jiang, Bo Zhang, Xuebing Leng, Ying-Long Guo, Xiao-Long Wan, Xingang Zhang*, Chang-Hua Ding* & Xue-Long Hou* Nat. Commun., 2021, 12, 6551.\r
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Visible-Light-Induced Palladium-Catalyzed Selective Defluoroarylation of Trifluoromethylarenes with Arylboronic Acids Yun-Cheng Luo, Fei-Fei Tong, Yanxia Zhang, Chun-Yang He, and Xingang Zhang* J. Am. Chem. Soc. 2021, 143, 13971-13979.\r
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Highly γ-Selective Arylation and Carbonylative Arylation of 3-Bromo-3,3-difluoropropene via Nickel Catalysis Ran Cheng, Yueqian Sang, Xing Gao, Shu Zhang, Xiao-Song Xue*, and Xingang Zhang* Angew. Chem. Int. Ed. 2021, 60, 12386-12391.\r
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Using Chlorotrifluoroethane for Tifluoroethylation of (Hetero)Aryl Bromides and Chlorides via Nickel Catalysis Xuefei Li, Xing Gao, Chun-Yang He, Xingang Zhang* Org. Lett. 2021, 23, 1400−1405.\r
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Access to α,α-Difluoro-γ-amino Acids by Nickel-Catalyzed Reductive Aryldifluoroacetylation of N-Vinylacetamide Qing-Wei Zhao, Zhi-Fang Yang, Xia-Ping Fu, Xingang Zhang* Synlett 2021, 32, 1565-1569.\r
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Nickel-Catalyzed Four-Component Carbocarbonylation of Alkenes under 1 atm of CO Minqi Zhou†, Hai-Yang Zhao†, Shu Zhang, Yanxia Zhang, and Xingang Zhang* J. Am. Chem. Soc. 2020, 142, 42, 18191–18199.\r
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Decarboxylative and Deaminative Alkylation of Difluoroenoxysilanes via Photoredox Catalysis: A General Method for Site-Selective Synthesis of Difluoroalkylated Alkanes Heng Song, Ran Cheng, Qiao-Qiao Min, Xingang Zhang* Org. Lett. 2020, 22, 7747-7751.\r
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Nickel-catalyzed regioselective coupling reaction of 3,3,3-trifluoropropene with arylzinc reagents Ran Cheng, Chang Xu, Xingang Zhang* Chin. J. Org. Chem. 2020, 40, 3307-3313\r
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Copper-Catalyzed Enantioselective Trifluoromethylthiolation of Secondary Propargyl Sulfonates Xing Gao, Yu-Lan Xiao, Shu Zhang, Jian Wu, and Xingang Zhang* CCS Chem. 2020, 2, 1463-1471. \r
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Nickel-Catalyzed Dicarbofunctionalization of Alkenes Yun-Cheng Luo, Chang Xu, Xingang Zhang* Chin. J. Chem. 2020, 38, 1371-1394.\r
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trans-Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides via Nickel Catalysis Chang Xu, Ran Cheng, Yun-Cheng Luo, Ming-Kuan Wang, and Xingang Zhang* Angew. Chem. Int. Ed. 2020, 59, 18741-18747. \r
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Stereoselective Functionalization of Racemic Cyclopropylzinc Reagents via Enantiodivergent Relay Coupling Lun An†, Fei-Fei Tong†, Shu Zhang and Xingang Zhang* J. Am. Chem. Soc. 2020, 142, 11884-11892\r
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Palladium Difluorocarbene Involved Catalytic Coupling with Terminal Alkynes Xue-Ying Zhang, Xia-Ping Fu, Shu Zhang, Xingang Zhang* CCS Chem. 2020, 2, 293–304.\r
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Nickel-Catalyzed Carbodifunctionalization of N-Vinylamides enables Access to γ-Amino Acids Zhi-Fang Yanga , Chang Xub , Xing Zheng*, Xingang Zhang* Chem. Commun, 2020, 56, 2642-2645\r
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Nickel-Catalyzed Carbonylation of Secondary Trifluoromethylated, Difluoromethylated, and Nonfluorinated Aliphatic Electrophiles with Arylboronic Acids under 1 atm of CO Ran Cheng, Hai-Yang Zhao, Shu Zhang, and Xingang Zhang* ACS Catal. 2020, 10, 36-42\r