个人简历

学习经历\r
1975 - 1978　上海第一医学院药学系\r
1980 - 1986　中国科学院上海有机化学研究所，研究生(导师：黄乃正教授与黄维垣研究员)\r
\r
工作经历\r
1978 - 1980　上海第一医学院药学系药化教研组，助教\r
1986 - 1987　中国科学院上海有机化学研究所，助研\r
1987 - 1989　德国科隆大学有机化学研究所，博士后（E. Vogel小组）\r
1989 - 1992　中国科学院上海有机化学研究所，助研\r
1992 - 1997　中国科学院上海有机化学研究所，副研究员\r
1997.9 - 中国科学院上海有机化学研究所，研究员\r
2006.7 - 2006.8 日本大阪大学访问教授\r
2010.2 - 2010.3 法国 Paul Sabatier大学访问教授

研究领域

"""""导向有机合成的金属有机化学\r
配体设计\r
不对称催化\r
有机小分子催化"

近期论文

Yan, X. X.; Liang, C. G.; Zhang, Y.; Hong, W.; Cao, B. X.; Dai, L. X.; Hou, X. L.*, Highly Enantioselective Pd-Catalyzed Allylic Alkylation of Acyclic Ketones, Angew. Chem. Int. Ed. 2005, 44, 6544-6546. \r
\r
Xiao-Xia Yan, Qian Peng, Yan Zhang, Kai Zhang, Wei Hong, Xue-Long Hou* and Yun-Dong Wu, A Highly Enantio- and Diastereoselective Cu-Catalytic 1,3-Dipolar Cycloaddition of Azomethine Ylides with Nitroalkenes, Angew. Chem. Int. Ed. 2006, 45, 1979-1983. \r
\r
Zheng, W.-H.; Zheng, B.-H.; Zhang, Y.; Hou, X.-L.*, Highly Regio-, Diastereo- and Enantioselective Pd-Catalyzed Allylic Alkylation of Acyclic Ketone Enolates with Monosubstituted Allyl Substrates, J. Am. Chem. Soc. 2007, 129, 7718-7719. \r
\r
Zhang, K.; Peng, Q.; Hou, X.-L.*; Wu, Y.-D., Highly Enantioselective Palladium-Catalyzed alkylation of Acyclic Amides, Angew. Chem. Int. Ed. 2008, 47, 1741. \r
\r
Wen-Qiong Wu, Qian Peng, Da-Xuan Dong, Xue-Long Hou* and Yun-Dong Wu*, A Dramatic Switch of Enantioselectivity in Asymmetric Heck Reaction by Benzylic Substituents of Ligands,J. Am. Chem. Soc. 2008, 129, 9717-9725. \r
\r
Xiao Xia Yan, Qian Peng, Qing Li, Kai Zhang, Jun Yao, Xue Long Hou*, Yun Dong Wu*, Highly Diastereoselectivity Switchable Enantioselective Mannich Reaction of Glycine Derivatives with Imines, J. Am. Chem. Soc. 2008, 130, 14362-14363. \r
\r
Wei Jing Lu, Yun Wei Chen, Xue Long Hou*, Iridium-Catalyzed Highly Enantioselective Hydrogenation of the C=C bond of α, β-Unsaturated Ketones, Angew. Chem. Int. Ed. 2008, 47, 10133-10136. \r
\r
Wei Liu, Di Chen, Xia-Zhen Zhu, Xiao-Long Wan and Xue-Long Hou*, Highly Diastereo- and Enantioselective Pd-Catalyzed Cyclopropanation of Acyclic Amides with Substituted Allyl Carbonates, J. Am. Chem. Soc. 2009, 131, 8734-8735.\r
\r
Lei, B.-L.; Ding, C.-H.; Yang, X.-F.; Wan, X.-L.; and Hou, X.-L.*, Highly Efficient Kinetic Resolution of 2-Substituted-2,3-Dihydro-4-Quinolones by Palladium-Catalyzed Asymmetric Allylic Alkylation, J. Am. Chem. Soc. 2009, 131, 18250-18251.\r
\r
Hai-Lin Liu, Di Chen, Xue-Long Hou*, Michal Sabat, and Lin Pu*, Highly Enantioselective Recognition of Structurally Diverse a-Hydroxycarboxylic Acids by a Fluorescent Sensor, Angew. Chem. Int. Ed. 2010, 49, 602-606.