个人简历

National Center for Nanoscience and Technology, Chinese Academy of Sciences\r
2017-2021 The Scripps Research Institute, La Jolla, CA, USA.Postdoctoral Research Associate; Advisor: Andrew B. Ward\r
2011-2016 The Biodesign Institute, Arizona State University, AZ, USA. Ph.D. in biochemistry; Advisor: Hao Yan\r
2007-2011 Tsinghua University, Beijing, P. R. China. B.S. in Chemistry, Advisor: Dongsheng Liu

研究领域

"""""Methodology development: putting enzymes on DNA scaffold.\r
In nature

近期论文

Effects of Univariate Stiffness and Degradation of DNA Hydrogels on the Transcriptomics of Neural Progenitor Cells. 2023. Journal of the American Chemical Society Bini Zhou, Bo Yang, Qian Liu, Lu Jin, Yu Shao, Taoyang Yuan, Ya-nan Zhang, Chao Wang, Ziwei Shi, Xin Li, Yufan Pan, Ning Qiao, Jiang-Fei Xu, Yuhe Renee Yang*, Yuanchen Dong, Lijin Xu, Songbai Gui*, and Dongsheng Liu*\r
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An Infectious Virus-like Particle Built on a Programmable Icosahedral DNA Framework. 2023. Angewandte Chemie 135 (4), e202214731 Y Xu, YR Yang, Q Shi, AB Ward, K Huang, X Chen, W Wang, Y Yang\r
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Cellular Ingestible DNA Nanostructures for Biomedical Applications. 2022. Advanced NanoBiomed Research, 2200119 R Xu, Y Li, C Zhu, D Liu*, YR Yang*\r
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Studies on the Synergistic Effect of Tandem Semi-Stable Complementary Domains on Sequence-Defined DNA Block Copolymers. 2022. Journal of the American Chemical Society Xin Li，Xiaobin Dai，Yufan Pan，Yawei Sun，Bo Yang，Kun Chen，You Wang，Jiang-Fei Xu ，Yuanchen Dong ，Yuhe Renee Yang*，Li-Tang Yan，Dongsheng Liu*\r
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A Biostable l-DNA Hydrogel with Improved Stability for Biomedical Applications. 2022.Angewandte Chemie. 61 (30), e202202520 Bo Yang, Bini Zhou, Cuifeng Li, Xiaowei Li, Ziwei Shi, Yuxin Li, Chenyou Zhu, Xin Li, Yi Hua, Yufan Pan, Jian He, Tianyang Cao, Prof. Yawei Sun, Prof. Wanli Liu, Min Ge, Prof. Yuhe R. Yang, Prof. Yuanchen Dong, Prof. Dongsheng Liu\r
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Influence of Tetra(ethylene glycol) (EG4) Substitution at the Loop Region on the Intramolecular DNA i-Motif.2012.Macromolecules 45:2643-2647. Yang Y, Sun Y, Yang Y, Xing Y, Zhang T, Wang Z, Yang Z, Liu D*.\r
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A DNA tweezer-actuated enzyme nanoreactor.2013.Nature communications 4:1-5.Liu M, Fu J, Hejesen C, Yang Y, Woodbury NW, Gothelf K, Liu Y, Yan H*.\r
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Directional regulation of enzyme pathways through the control of substrate channeling on a DNA origami scaffold.2016.Angewandte Chemie International Edition 55:7483-7486.Ke G, Liu M, Jiang S, Qi X, Yang YR, Wootten S, Zhang F, Zhu Z, Liu Y, Yang CJ*.\r
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Cuboid Vesicles Formed by Frame‐Guided Assembly on DNA Origami Scaffolds.2017.Angewandte Chemie International Edition 56:1586-1589.Dong Y, Yang YR, Zhang Y, Wang D, Wei X, Banerjee S, Liu Y, Yang Z, Yan H, Liu D*.\r
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The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization.2019.Cell reports 27:586-598. e6.Lei L, Yang YR, Tran K, Wang Y, Chiang C-I, Ozorowski G, Xiao Y, Ward AB, Wyatt RT, Li Y*.\r
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A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice.2020.Vaccines 2020, 8, 389.Thrane, S., Aves, K.-L., Uddbäck, I.E.M., Janitzek, C.M., Han, J., Yang, Y.R., Ward, A.B., Theander, T.G., Nielsen, M.A., Salanti, A., Thomsen, A.R., Christensen, J.P., Sander, A.F.\r
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Germinal centre-mediated diversification of human B cell response to influenza vaccination.2020.Nature 586: 127-131.Turner JS†, Zhou JQ†, Han J†, Schmitz AJ, Rizk A, Al-Soussi W, Lei, T, Amor M, McIntire KM, Meade P, Strohmeier S, Brent R, Richey S, Haile A, Yang YR, Klebert M, Suessen T, Teefey S, Presti R, Krammer F, Kleinstein SH, Ward AB, Ellebedy AH*.\r
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Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat.2018.Nature nanotechnology 13:723-729.Li J, Johnson-Buck A, Yang YR, Shih WM, Yan H, Walter NG*.\r
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DNA nanostructures as programmable biomolecular scaffolds.2015.Bioconjugate chemistry 26:1381-1395. Yang YR, Liu Y, Yan H*.\r
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Assembly of multienzyme complexes on DNA nanostructures.2016. Nature protocols 11:2243.Fu J, Yang YR, Dhakal S, Zhao Z, Liu M, Zhang T, Walter NG, Yan H*.\r
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2D Enzyme Cascade Network with Efficient Substrate Channeling by Swinging Arms. 2018. ChemBioChem 19:212-216.Yang YR, Fu J, Wootten S, Qi X, Liu M, Yan H, Liu Y*.\r
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Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits.2020. Journal of Virology 94 (7), e01861-19.Yang YR†, McCoy LE†, van Gils MJ, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, Ward AB*.\r
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Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm.2014,Nature nanotechnology 9:531. Fu J†, Yang YR†, Johnson-Buck A, Liu M, Liu Y, Walter NG, Woodbury NW, Yan H*.\r