个人简历

国家杰出青年获得者（2001年），现任中科院过程工程研究所生化工程国家重点实验室主任，中国颗粒学会副理事长，中国化工学会生物化工专业委员会副主任委员，中国生物工程学会理事，国际期刊J Microencapsulation、Frontier of Chemical Science and Engineering编委。 \r
\r
1984年公派去日本读大学本科，1988年获得日本群马大学纤维高分子工学科学士学位，1990和1993年分别获东京工业大学高分子工学科硕士和博士学位。1994年-2001年任东京农工大学生物系统应用科学研究科的Assistant Professor，任中国科学院过程工程研究所研究员，博士生导师。

研究领域

"""""目前研究方向为均一高分子微球和微囊的制备及在生化工程和医学工程中的应用，研究和开发用于生化分离、药物载体、免疫佐剂（疫苗递送系统）、细胞培养微载体、酶固定化载体的重要产品；同时进行长效蛋白质药物制剂、黏膜给药凝胶制剂、抗癌剂靶向性载体的设计、制备和应用研究。"

近期论文

Preparation of ropivacaine loaded PLGA microspheres as controlled-release system with narrow size distribution and high loading efficiency., Colloids and Surfaces a-Physicochemical and Engineering Aspects, 2019, 通讯作者\r
\r
The Horizon of the Emulsion Particulate Strategy: Engineering Hollow Particles for Biomedical Applications., Advanced Materials, 2019, 通讯作者\r
\r
Imitation of nature: Bionic design in the study of particle adjuvants, Journal of Controlled Release, 2019, 通讯作者\r
\r
Preparation of double-emulsion-templated microspheres withcontrollable porous structures by premix membrane emulsification, Particuology, 2019, 通讯作者\r
\r
Cell Membrane Camouflaged Hydrophobic Drug Nanoflake Sandwiched with Photosensitizer for Orchestration of Chemo-Photothermal Combination Therapy., Small, 2019, 通讯作者\r
\r
Fabrication of rigid and macroporous agarose microspheres by pre-cross-linking and surfactant micelles swelling method., Colloids and Surfaces B-Biointerfaces, 2019, 通讯作者\r
\r
Exosomes: The Indispensable Messenger in Tumor Pathogenesis and the Rising Star in Antitumor Applications., Advanced Biosystems, 2019, 通讯作者\r
\r
The molecular mechanism of robust macrophage immune responses induced by PEGylated molybdenum disulfide?, Nanoscale, 2019, 通讯作者\r
\r
Exploiting the Lymph-Node-Amplifying Effect for Potent Systemic and Gastrointestinal Immune Responses via Polymer/Lipid Nanoparticles., ACS Nano, 2019, 通讯作者\r
\r
Recent advances in particulate adjuvants for cancer vaccination, Advanced Therapeutics, 2019, 通讯作者\r
\r
A minimalist peptide ligand for IgG by minimizing the binding domain of protein A, Biochemical Engineering Journal, 2019, 通讯作者\r
\r
Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects, Frontiers of Chemical Science and Engineering, 2019, 通讯作者\r
\r
Bridging Systemic Immunity with Gastrointestinal Immune Responses via Oil-in-Polymer Capsules., Advanced Materials, 2018, 通讯作者\r
\r
Cancer Cell Membrane-Biomimetic Nanoprobes with Two-Photon Excitation and Near-Infrared Emission for Intravital Tumor Fluorescence Imaging., ACS Nano, 2018, 通讯作者\r
\r
Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification., Progress in Chemistry, 2018, 通讯作者\r
\r
Exploration of Antigen Induced CaCO3 Nanoparticles for Therapeutic Vaccine., Small, 2018, 通讯作者\r
\r
The interacting role of physical stiffness and tumor cells on the macrophages polarization., Colloids and Surfaces a-Physicochemical and Engineering Aspects, 2018, 通讯作者\r
\r
Lymph Node-Targeting Nanovaccine through Antigen-CpG Self-Assembly Potentiates Cytotoxic T Cell Activation., Journal of Immunology Research, 2018, 通讯作者\r
\r
Macrophage responses to the physical burden of cell-sized particles., Journal of Materials Chemistry B, 2018, 通讯作者\r
\r
Uniform polysaccharide composite microspheres with controllable network by microporous membrane emulsification technique., Analytical and Bioanalytical Chemistry, 2018, 通讯作者