个人简历
招生方向医学图像处理人工智能与医学大数据脑网络及其临床应用教育背景2005-09--2008-06 中国科学院自动化研究所 模式识别国家重点实验室 工学博士2002-09--2005-08 北京工业大学 应用数理学院 理学硕士1998-09--2002-08 曲阜师范大学 数学系 理学学士工作简历2017-05~现在, 中国科学院大学 人工智能学院, 研究员2016-10~现在, 中国科学院自动化研究所, 研究员2014-04~2016-09,中国科学院自动化研究所, 项目研究员2011-11~2014-03,中国科学院自动化研究所, 副研究员2011-04~2012-03,剑桥大学 Brain Mapping Unit, 访问学者2008-07~2011-09,中国科学院自动化研究所 模式识别国家重点实验室, 助理研究员教授课程脑网络组学基础及应用脑-机接口技术医学图像分析机器学习在医学数据中的应用基于功能磁共振的脑网络研究进展奖励信息（1） 吴文俊人工智能科学奖自然科学奖, 一等奖, 部委级, 2019（2） 北京市科技新星, , 省级, 2015（3） 卢嘉锡青年人才奖, , 院级, 2013（4） SCOPUS青年科学之星, , 其他, 2011（5） 中国科学院优秀博士论文, , 院级, 2009（6） 中国科学院院长优秀奖, , 院级, 2008（7） 北京市科技进步奖, 三等奖, 省级, 2008专利成果（ 1 ） 基于自注意力机制的脑疾病分类系统, 发明, 2018, 第 1 作者, 专利号: 201810739141.3（ 2 ） 基于对抗神经网络的医学图像合成方法、分类方法及装置, 发明, 2019, 第 1 作者, 专利号: 201910211463.5出版信息所有的工作都以智能医学影像为主核，以脑影像在重大神经精神疾病中的应用为导向展开研究。到目前为止，以共同通讯作者发表学术论文26篇、第一作者(共同第一作者)发表SCI论文16篇, 包括Advanced Science, Brain ( 2篇), Science Bulletin ( 2篇), Cerebral Cortex ( 2篇), Neuroimage ( 2篇), IEEE Journal of Selected Topics in Signal Processing等 。开发Brainnetome fMRI Toolkit (http://brant.brainnetome.org)科研项目（ 1 ） 轻度认知损害及阿尔茨海默病的多模态脑影像研究和早期诊断系统, 主持, 国家级, 2009-01--2012-12（ 2 ） 盲人脑网络可塑性的磁共振影像研究, 主持, 国家级, 2009-01--2012-12（ 3 ） 阿尔茨海默病的多模态脑影像研究和早期诊断系统研究, 主持, 部委级, 2011-05--2013-05（ 4 ） 盲人脑网络可塑性的磁共振影像研究, 主持, 部委级, 2010-06--2013-06（ 5 ） 脑网络计算方法及在盲人中的应用研究, 主持, 国家级, 2010-06--2011-06（ 6 ） 精神分裂症记忆障碍的脑网络组学研究, 参与, 国家级, 2012-01--2015-12（ 7 ） 盲人视皮层跨模态感觉重组的脑网络表征研究, 主持, 国家级, 2012-01--2016-12（ 8 ） 基于多中心多模态磁共振影像的阿尔茨海默病及高危人群的情景记忆脑网络表征研究, 主持, 国家级, 2016-01--2019-12（ 9 ） 危险因素靶向干预与神经环路再激活, 主持, 国家级, 2016-09--2020-12（ 10 ） 基于多模态磁共振影像的阿尔茨海默早期识别研究-协和医院委托, 主持, 研究所（学校）, 2018-01--2020-12（ 11 ） 基于多中心磁共振影像组学的阿尔茨海默病早期诊断关键技术研究, 主持, 国家级, 2019-01--2022-12（ 12 ） 基于多中心的磁共振的阿尔茨海默病早期识别研究, 主持, 部委级, 2018-01--2022-12（ 13 ） 北京市杰出青年基金--面向阿尔茨海默病早期精准识别的方法研究和系统构建, 主持, 省级, 2020-10--2023-12参与会议（1）Altered Fingerprinting of Radiomics Architecture in AD 第七届神经信息国际研讨会暨首届三晋国际精神医学论坛 2018-11-15（2）Altered Fingerprinting of Radiomics and Connectomics Architecture in Alzheimer Disease based on Multicenter MRI 精神健康技术中英青年学者双边研讨会 2018-09-07（3）Altered Fingerprinting of Radiomics Architecture in AD 2018-05-22（4）阿尔茨海默病脑功能网络异常多中心研究初探 2017年图像计算与数字医学国际研讨会（ISICDM 2017） 2017-09-23（5）基于多中心磁共振影像的阿尔茨海默病脑网络可重复性研究及动态变化 2017-08-27（6）Impaired Brain Network in Alzheimer Disease based on Multicenter fMRI data 2016-10-20（7）Impaired Brain Network Architecture of Alzheimer Disease based on Multicenter resting fMRI 2016-09-24（8）Altered Network Properties in Schizophrenia Liu Yong 2011-04-15（9）无 医学影像与计算机辅助干预 2010 年会 无 2010-09-20（10）Resting-state fMRI and Schizophrenia Liu Yong 2009-07-24（11）Altered Network Properties in Schizophrenia Liu Yong 2009-07-08（12）Altered Functional Connectivity in Early Blind Liu Yong 2009-04-05（13）Decreased Information Transmission Efficiency in Schizophrenia Liu Yong 2008-06-15
研究领域
"医学大数据计算模式识别与智能系统医学影像智能系统"
近期论文
（1） Grab-AD: Generalizability and Reproducibility of Altered Brain Activity and Diagnostic Classification in Alzheimer's Disease, Human Brain Mapping, 2020, 通讯作者（2） Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer’s disease: diagnosis, longitudinal progress and biological basis, Science Bulletin, 2020, 通讯作者（3） Aberrant hippocampal functional connectivity is associated with fornix white matter integrity in Alzheimer’s disease and mild cognitive impairment, Journal of Alzheimer Disease, 2020, 通讯作者（4） A neuroimaging biomarker for striatal dysfunction in schizophrenia, Nature Method, 2020, 第 6 作者（5） Characterizing white matter connectivity in Alzheimer’s disease and mild cognitive impairment: An automated fiber quantification analysis with two independent datasets, Cortex, 2020, 通讯作者（6） Default mode network integrity changes contribute to cognitive deficits in subcortical vascular cognitive impairment, no dementia, Brain Imaging Behav, 2020, 第 8 作者（7） Generalizable, reproducible, and neuroscientifically interpretable imaging biomarkers for Alzheimer's Disease, Advanced Science, 2020, 通讯作者（8） The Efficacy of COGnitive tRaining in patiEnts with Amnestic mild coGnitive impairmENT (COG-REAGENT): Protocol for a Multi-Center Randomized Controlled Trial, Journal of Alzheimer Disease, 2020, 第 10 作者（9） Dysfunctional Architecture Underlies White Matter Hyperintensities with and without Cognitive Impairment, J Alzheimers Dis., 2019, 通讯作者（10） ASAF: altered spontaneous activity fingerprinting in Alzheimer’s disease based on multisite fMRI, Science Bulletin, 2019, 通讯作者（11） A neural circuit for comorbid depressive symptoms in chronic pain, Nat Neurosci, 2019, 其他（合作组作者）（12） KIBRA and APOE Gene Variants Affect Brain Functional Network Connectivity in Healthy Older People, J Gerontol A Biol Sci Med Sci, 2019, 其他（合作组作者）（13） Intrinsic connectivity identifies the sensory-motor network as a main cross-network between remitted late-life depression- and amnestic mild cognitive impairment-targeted networks, Brain Imaging Behav, 2019, 通讯作者（14） IDH mutation-specific radiomic signature in lower-grade gliomas, Aging (Albany NY), 2019, 其他（合作组作者）（15） Linked 4-Way Multimodal Brain Differences in Schizophrenia in a Large Chinese Han Population, Schizophr Bull, 2019, 其他（合作组作者）（16） Radiomics based on multicontrast MRI can precisely differentiate among glioma subtypes and predict tumour-proliferative behaviour, Eur Radiol, 2019, 通讯作者（17） Polygenic effects of schizophrenia on hippocampal grey matter volume and hippocampus-medial prefrontal cortex functional connectivity, Br J Psychiatry, 2019, 第 3 作者（18） MIR137 polygenic risk is associated with schizophrenia and affects functional connectivity of the dorsolateral prefrontal cortex, Psychol Med, 2019, 第 3 作者（19） Attention-based 3D Convolutional Network for Alzheimer’s Disease Diagnosis and Biomarkers Exploration, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), 2019, 通讯作者（20） Characterizing white matter connectivity in Alzheimer’s disease and mild cognitive impairment: Automated fiber quantification, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), 2019, 通讯作者（21） Radiomic Features of Hippocampal Subregions in Alzheimer’s Disease and Amnestic Mild Cognitive Impairment, Frontiers in Aging Neuroscience, 2018, 通讯作者（22） Core networks and their reconfiguration patterns across cognitive loads, Hum Brain Mapp, 2018, 第 3 作者（23） Both activated and less-activated regions identified by functional MRI reconfigure to support task executions, Brain Behav, 2018, 第 3 作者（24） Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations, Neurobiol Aging, 2018, 第 7 作者（25） BRANT: A Versatile and Extendable Resting-state fMRI Toolkit, Front. Neuroinform, 2018, 通讯作者（26） Test-retest Reliability of Functional Connectivity and Graph Metrics in the Resting Brain Network, IEEE EMBC, 2018, 通讯作者（27） Visual deprivation selectively reshapes the intrinsic functional architecture of the anterior insula subregions, Sci Rep, 2017, 第 7 作者（28） Aberrant Functional Connectivity Architecture in Participants with Chronic Insomnia Disorder Accompanying Cognitive Dysfunction: A Whole-Brain, Data-Driven Analysis, Front Neurosci, 2017, 第 7 作者（29） Early classification of Alzheimer's disease using hippocampal texture from structural MRI, Proc. SPIE 10137, Medical Imaging 2017, 2017, 通讯作者（30） Distinct Changes in Functional Connectivity in Posteromedial Cortex Subregions during the Progress of Alzheimer's Disease, Front Neuroanat, 2017, 第 3 作者（31） Longitudinal study of impaired intra- and inter-network brain connectivity in subjects at high risk for Alzheimer's disease, J Alzheimers Dis, 2016, 通讯作者（32） Connectivity Profiles Reveal a Transition Subarea in the Parahippocampal Region That Integrates the Anterior Temporal-Posterior Medial Systems, J Neurosci, 2016, 第 3 作者（33） Altered Intranetwork and Internetwork Functional Connectivity in Type 2 Diabetes Mellitus With and Without Cognitive Impairment, Sci Rep, 2016, 通讯作者（34） Network-Based Statistic Show Aberrant Functional Connectivity in Alzheimer's Disease, Ieee Journal of Selected Topics in Signal Processing, 2016, 通讯作者（35） Convergent and divergent intranetwork and internetwork connectivity patterns in patients with remitted late-life depression and amnestic mild cognitive impairment, Cortex, 2016, 通讯作者（36） Impaired Parahippocampus Connectivity in Mild Cognitive Impairment and Alzheimer's Disease, Impaired Parahippocampus Connectivity in Mild Cognitive Impairment and Alzheimer's Disease, J Alzheimers Dis, 2016, 通讯作者（37） Aberrant intra- and inter-network connectivity architectures in Alzheimer's disease and mild cognitive impairment, Sci Rep, 2015, 通讯作者（38） Aberrant Functional Connectivity Architecture in Alzheimer's Disease and Mild Cognitive Impairment: A Whole-Brain, Data-Driven Analysis, Biomed Res Int, 2015, 通讯作者（39） Functional Connectivity Density in Congenitally and Late Blind Subjects, Cereb Cortex, 2015, 第 3 作者（40） Multiple Effect of APOE Genotype on Clinical and Neuroimaging Biomarkers Across Alzheimer's Disease Spectrum, Mol Neurobiol, 2015, 第 4 作者（41） Co-activation Probability Estimation (CoPE): An approach for modeling functional co-activation architecture based on neuroimaging coordinates, Neuroimage, 2015, 第 4 作者（42） Convergent functional architecture of the superior parietal lobule unraveled with multimodal neuroimaging approaches, Convergent functional architecture of the superior parietal lobule unraveled with multimodal neuroimaging approaches, Human Brain Mapping, 2015, 第 6 作者（43） Impaired Long Distance Functional Connectivity and Weighted Network Architecture in Alzheimers Disease, Cerebral Cortex, 2014, 第 1 作者（44） Altered functional connectivity of the marginal division in Alzheimers disease, Curr Alzheimer Res, 2014, 通讯作者（45） Grey-matter volume as a potential feature for the classification of Alzheimers disease and mild cognitive impairment an exploratory study, Grey-matter volume as a potential feature for the classification of Alzheimers disease and mild cognitive impairment an exploratory study, Neurosci Bull, 2014, 通讯作者（46） Longitudinal alteration of amygdalar functional connectivity in mild cognitive impairment subjects revealed by resting-state FMRI., Longitudinal alteration of amygdalar functional connectivity in mild cognitive impairment subjects revealed by resting-state FMRI., Brain Connect, 2014, 通讯作者（47） Altered resting-state network connectivity in congenital blind, Altered resting-state network connectivity in congenital blind, Human Brain Mapping, 2014, 第 1 作者（48） Functional Connectivity Density in Congenitally and Late Blind Subjects, Functional Connectivity Density in Congenitally and Late Blind Subjects, Cerebral Cortex, 2014, 第 3 作者（49） Abnormal salience network in normal aging and in amnestic mild cognitive impairment and Alzheimers disease., Abnormal salience network in normal aging and in amnestic mild cognitive impairment and Alzheimers disease., Human Brain Mapping, 2014, 第 1 作者（50） Impaired functional connectivity of the thalamus in alzheimer s disease and mild cognitive impairment: a resting-state FMRI study, Curr Alzheimer Res, 2013, 通讯作者（51） Altered spontaneous activity in Alzheimers disease and mild cognitive impairment revealed by Regional Homogeneity, NeuroImage, 2012, 第 1 作者（52） Onset age of blindness affects the anatomical network constructed by diffusion tensor tractography, Cerebral Cortex, 2012, 第 1 作者（53） Disrupted small-world brain networks in moderate Alzheimers disease: a resting-state FMRI study, Plos ONE, 2012, 第 1 作者（54） Discriminant analysis of functional connectivity patterns on Grassmann manifold, NeuroImage, 2011, 第 2 作者（55） Functional segregation of the human cingulate cortex is confirmed by functional connectivity based neuroanatomical parcellation, NeuroImage, 2011, 第 1 作者（56） Increased regional homogeneity of blood oxygen level-dependent signals in occipital cortex of early blind individuals, NeuroReport, 2011, 第 1 作者（57） Brain anatomical network and intelligence, PLoS Computational Biology, 2009, 第 1 作者（58） Altered anatomical network in early blindness revealed by diffusion tensor tractography, Plos ONE, 2009, 第 1 作者（59） Modified periodogram method for estimating the Hurst exponent of fractional Gaussian noise, Physical Review E, 2009, 第 2 作者（60） Default network and intelligence difference, IEEE Transactions on Autonomous Mental Development, 2009, 第 2 作者（61） Disrupted small-world networks in schizophrenia., Brain, 2008, 第 1 作者（62） Regional homogeneity, functional connectivity and imaging markers of Alzheimers disease: a review of resting-state fMRI studies, Neuropsychologia, 2008, 第 1 作者（63） Altered functional connectivity of primary visual cortex in early blindness, Human Brain Mapping, 2008, 第 1 作者（64） Whole brain functional connectivity in the early blind, Brain, 2007, 第 1 作者2020-01-01-今,Journal of Alzheimer Disease, Senior Editor2019-12-01-今,NeuroScience Bulletin, 青年编委2019-03-30-今,中国图象图形学会, 脑图谱专业委员会2018-11-01-今,中国图学学会 图学大数据 专业委员会, 委员2018-06-01-今,北京医学会神经病学分会痴呆与认知障碍学组, 委员2018-05-01-今,Frontiers in Aging Neuroscience., Review Editor2018-01-01-今,中国微循环学会神经变性病专业委员会, 委员2017-04-30-今,中国医疗保健国际交流促进会认知障碍分会, 青年副主任委员2016-10-01-今,中国科学院青年促进会北京分会, 理事2016-01-01-今,MICS青年委员会, 委员2015-12-31-2021-12-31,北京市神经学会, 青年理事2015-12-30-2020-12-31,Journal of Alzheimer Disease, Associate Editor2013-05-01-今,PLoS One, Editor2009-09-20-2010-09-24,MICCAI 2010 组委会, 成员
