热点话题人物,欢迎提交收录!
最优雅的名人百科,欢迎向我们提交收录。
郭惠珊
2023-05-16 15:03
  • 郭惠珊
  • 郭惠珊 - 博导-中国科学院大学-现代农业科学学院-个人资料

近期热点

资料介绍

个人简历


招生专业
071007-遗传学
招生方向
植物RNA沉默及其抗病应用,真菌致病性研究
教育背景
1993-06--1996-06 西班牙马德里大学 博士
1983-09--1987-07 中山大学 学士
学历
中山大学生物学,学士
学位
西班牙马德里大学, 博士
出国学习工作
1992-1993 西班牙马德里大学\

研究领域


"RNA沉默是一种在动植物中广泛存在的抵抗外源RNA和病毒的适应性免疫反应机制。能产生信号并系统运输是植物RNA沉默最重要的特征,即系统RNA沉默,也是植物抗病毒最关键的一环。另外,siRNA参与DNA甲基化和染色质重塑,使RNA沉默成为表观遗传学 (Epigenetic)研究领域的重要课题。本研究组以模式植物拟南芥、烟草和重要的经济作物棉花为寄主材料,以病毒和真菌为病原微生物,围绕植物RNA沉默和miRNA调控途径,以及其他受病原影响的调控途径开展病原微生物-寄主的相互作用研究,剖析植物致病机理。目前开展以下两方面的研究:
1、植物RNA沉默的分子机制及其抗病应用研究;
2、植物与真菌的互作机理及维管束真菌病害的防控策略研究。"

近期论文


(1) A Brassica miRNA Regulates Plant Growth and Immunity through Distinct Modes of Action, Molecular Plant, 2020, 通讯作者
(2) Verticillium dahliae chromatin remodeling facilitates the DNA damage repair in response to plant ROS stress, PLoS Pathog, 2020, 通讯作者
(3) IBM1-dependent H3K9 demethylation enables self-silencing of an exogenous silencer for the non-cell autonomous silencing of an endogenous target gene, J Genet Genomics, 2019, 通讯作者
(4) A fungal milRNA mediates epigenetic repression of a virulence gene in Verticillium dahliae, Philosophical Transactions of the Royal Society B-Biological Sciences, 2019, 通讯作者
(5) Trans-kingdom RNA interactions drive the evolutionary arms race between hosts and pathogens, Curr Opin Genet Dev, 2019, 通讯作者
(6) Deacetylation of chitin oligomers increases virulence in soil-borne fungal pathogens, Nat Plants, 2019, 通讯作者
(7) Trans-Kingdom RNA Silencing in Plant-Fungal Pathogen Interactions, Mol Plant, 2018, 通讯作者
(8) The plant specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity, Elife, 2018, 通讯作者
(9) Genome-wide profiling of sRNAs in the Verticillium dahliae-infected Arabidopsis roots, Mycology, 2018, 通讯作者
(10) CMV2b-Dependent Regulation of Host Defense Pathways in the Context of Viral Infection, Viruses, 2018, 通讯作者
(11) The Verticillium-specific protein VdSCP7 localizes to the plant nucleus and modulates immunity to fungal infections, New Phytologist, 2017, 通讯作者
(12) Secretory proteins are delivered to the septin-organized penetration interface during root infection by Verticillium dahliae, PLoS Pathogens, 2017, 通讯作者
(13) Expression of pathogenesis-related genes in cotton roots in response to Verticillium dahliae PAMP molecules, SCIENCE CHINA Life Sciences, 2017, 通讯作者
(14) The dual edge of RNA silencing suppressors in the virus–host interactions, Current Opinion in Virology, 2016, 通讯作者
(15) Host-Induced Gene Silencing of the Target Gene in Fungal Cells Confers Effective Resistance to the Cotton Wilt Disease Pathogen Verticillium dahliae, Molecular Plant, 2016, 通讯作者
(16) CMV2b-AGO Interaction Is Required for the Suppression of RDR-Dependent Antiviral Silencing in Arabidopsis, Front Microbiol, 2016, 通讯作者
(17) An improved single-step cloning strategy simplifies the Agrobacterium tumefaciens-mediated transformation (ATMT)-based gene disruption method in Verticillium dahliae, Phytopathology, 2016, 通讯作者
(18) Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen, Nat Plants, 2016, 通讯作者
(19) Hyphopodium-Specific VdNoxB/VdPls1- Dependent ROS-Ca2+ Signaling Is Required for Plant Infection by Verticillium dahliae, PLOS Pathogens, 2016, 通讯作者
(20) Cleavage ofINDOLE-3-ACETIC ACID INDUCIBLE28mRNA by MicroRNA847 Upregulates Auxin Signaling to Modulate Cell Proliferation and Lateral Organ Growth in Arabidopsis, Plant Cell, 2015, 通讯作者
(21) Nicotiana Small RNA Sequences Support a Host Genome Origin of Cucumber Mosaic Virus Satellite RNA, PLoS Genetics, 2015, 通讯作者
(22) Arabidopsis Leaf Explant Culture, Bio-protocal, 2015, 通讯作者
(23) Satellite RNAs interfere with the function of viral RNA silencing suppressors, Frontiers in Plant Science, 2015, 第 4 作者
(24) Colonization process of Arabidopsis thaliana roots by a green fluorescent protein-tagged isolate of Verticillium dahliae, Protein Cell, 2014, 通讯作者
(25) C2-mediated decrease in DNA methylation, accumulation of siRNAs, and increase in expression for genes involved in defense pathways in plants infected with beet severe curly top virus, The Plant Journal , 2013, 通讯作者
(26) Inhibition ofin vivo Slicer activity of Argonaute protein 1 by the viral 2b protein independent of its dsRNA-binding function, Molecular Plant Pathology, 2013, 通讯作者
(27) The role of virus-derived small interfering RNAs in RNA silencing in plants, Sci China Life Sci , 2012, 通讯作者
(28) Molecular characterization and functional analysis of a necrosis- and ethylene-inducing, protein-encoding gene family from Verticillium dahliae, Mol Plant Microbe Interact, 2012, 通讯作者
(29) Identification and characterization of small RNAs in the hyperthermophilic archaeon Sulfolobus solfataricus, PLoS One, 2012, 通讯作者
(30) Application of RNA silencing to plant disease resistance, Silence , 2012, 通讯作者
(31) Suppression of Arabidopsis ARGONAUTE1-Mediated Slicing, Transgene-Induced RNA Silencing, and DNA Methylation by Distinct Domains of the Cucumber mosaic virus 2b Protein, Plant Cell, 2012, 通讯作者
(32) 植物基因组的安全防线, 生物工程学报, 2012, 通讯作者
(33) 植物中病毒来源的小RNA 介导的RNA 沉默, 中国科学, 2012, 通讯作者
(34) Satellite RNA reduces expression of the 2b suppressor protein resulting in the attenuation of symptoms caused by Cucumber mosaic virus infection, Molecular Plant Pathology, 2011, 通讯作者
(35) BSCTV C2 Attenuates the Degradation of SAMDC1 to Suppress DNA Methylation-Mediated Gene Silencing in Arabidopsis, The Plant Cell, 2011, 第 4 作者
(36) Satellite RNA-derived small interfering RNA satsiR-12 targeting the 3 untranslated region of Cucumber mosaic virus triggers viral RNAs for degradation, Journal of Virology, 2011, 通讯作者
(37) A Glutamic Acid-Rich Protein Identified in Verticillium dahliae from an Insertional Mutagenesis Affects Microsclerotial Formation and Pathogenicity, PLoS ONE, 2010, 通讯作者
(38) RNA-dependent RNA polymerase 1 from Nicotiana tabacum suppresses RNA silencing and enhances viral infection in N. benthamiana, The Plant Cell, 2010, 通讯作者
(39) An efficient system to detect protein ubiquitination by argoinfiltration in Nicotiana benthamiana, The Plant Journal, 2010, 第 4 作者
(40) Up-regulation of LSB1/GDU3 impacts geminivirus infection by activating the salicylic acid pathway, The Plant Journal, 2010, 第 4 作者
(41) Involvement of C4 Protein of Beet Severe Curly Top Virus (Family Geminiviridae) in Virus Movement, PLoS ONE, 2010, 第 4 作者
(42) A large insert Thellungiella halophila BIBAC library for genomics and identification of stress tolerance genes, Plant Molecular Biology, 2010, 第 4 作者
(43) Potential coexistence of both bacterial and eukaryotic small RNA biogenesis and functional related protein homologs in Archaea, Journal of Genetics and Genomics, 2010, 通讯作者
(44) RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle, The Plant Journal, 2009, 第 4 作者
(45) Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice, Vaccine, 2009, 第 4 作者
(46) Artificial microRNAs highly accessible to targets confer efficient virus resistance in plants, Journal of Virology, 2008, 通讯作者
(47) Characterization of conserved and novel microRNAs and their targets, including a TuMV-induced TIR-NBS-LRR class R gene-derived novel miRNA in Brassica, FEBS letter, 2008, 通讯作者
(48) Delayed resistance to Cucumber Mosaic Virus mediated by 3’UTR derived hairpin RNA, Chinese Science Bulletin , 2008, 通讯作者
(49) RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle, The Plant Journal, 2008, 第 4 作者
(50) Antiviral Defense in Plants, Plant Viruses  Global Science Books, 2007, 通讯作者
(51) DCL4 targets Cucumber mosaic virus satellite RNA at novel secondary structures, Journal of Virology, 2007, 通讯作者
(52) SDIR1 Is a RING Finger E3 Ligase That Positively Regulates Stress-Reponsive Abscicic Acid Signaling in Arabidopsis, The Plant Cell, 2007, 第 4 作者
(53) Regulation of microRNA on plant development and viral infection, Chinese Science Bulletin, 2006, 通讯作者
(54) Systemic antiviral silencing in plants, Virus Reseach, 2006, 通讯作者
(55) microRNA 对植物生长发育和病毒侵染的调控, 科学通报, 2006, 通讯作者
(56) MicroRNA directs mRNA cleavage of the transcription factor NAC1 to downregulate auxin signals for arabidopsis lateral root development, Plant Cell, 2005, 第 1 作者
2018-01-01-今,PBJ Editorial Board, Editorial Board
2018-01-01-今,MPP Editorial Board, Editorial Board
2017-11-01-今,生物工程学报, 副主编
2017-08-01-今,植物基因组学国家重点实验室学术委员会, 副主任
2017-05-31-今,中国科学院微生物研究所招生小组, 成员
2014-12-31-2017-12-30,Molecular Plant Pathogens 编委, Editorial Board
2014-01-02-今,中国科学院微生物研究所学术道德与权益委员会, 委员
2014-01-01-2018-12-31,中国植物病理学会第十届理事会, 理事
2014-01-01-今,中国科学院微生物研究所第一届研究组长委员会, 委员
2013-12-31-今,BMC genomics 编委, Associate Editor
2013-11-04-今,中国科学院微生物研究所学术委员会, 委员
2013-01-31-今,PLoS Pathogens 编委, Associate Editor
2013-01-01-今,中国科学院微生物研究所第八届学位评定委员会, 委员
2012-12-31-2015-12-30,Molecular Plant-Microbe Interact ions编委,
2011-12-21-今,植物基因组学国家重点实验室第三届学术委员会, 委员

相关热点

扫码添加好友