个人简历

常江：研究员、博士生导师，中国科学院上海硅酸盐研究所生物材料与组织工程研究中心主任。国际生物材料学会联合会Fellow（FBSE），国际可注射骨与关节材料学会副主席，美国生物材料学会会员，国际组织工程学会会员，中国生物材料学会常务理事，中国生物医学工程学会生物材料专委会委员，全国外科植入物和矫形器械标准化技术委员会骨科植入物分技委委员，上海生物医学工程学会理事。国际学术期刊Ceramics International编委。\r
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1991年德国达姆施达特工业大学获博士学位，1991年至2000年分别在德国卢卑克医科大学做博士后研究、新西兰奥克兰大学任研究员、美国纽约大学任研究助理教授、美国强生公司损伤修复技术中心任研究员，主要从事组织损伤修复及组织工程生物材料研究，包括皮肤、骨、软骨的组织工程再生修复。1996年获新西兰职业华人杰出成就奖。 2000年应聘回国，到中国科学院上海硅酸盐研究所从事科研工作。回国后创建了中科院上海硅酸盐研究所生物材料与组织工程研究中心，组建了生物材料研究团队。针对生物材料在人体组织创伤修复中的应用，系统地开展了在国际上具有特色的硅酸盐生物活性材料为主体的生物陶瓷及其复合材料、组织工程材料、纳米生物材料等方面的基础研究、应用研究、产品开发和产业化。与美国、日本、荷兰等国家的大学和科研机构建立了科研合作和学术交流关系。

研究领域

"""""组织再生与损伤修复材料（包括硬组织和多种软组织如骨、牙、皮肤、软骨、肌腱、血管、神经、心肌、脂肪、肝脏、肺等），抗菌生物材料，药物缓释材料，以及生物材料与细胞的相互作用（包括对干细胞以及免疫细胞的调控）。"

近期论文

Xiaoguo Liu, Kaili Lin, Chengtie Wu, Yueyue Wang, Zhaoyong Zou, Jiang Chang*. Multilevel hierarchically ordered artificial biomineral. 2014, Small 10(1):152-159.\r
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Haiyan Li, Ke Xue, Ni Kong, Kai Liu*, Jiang Chang*. Silicate bioceramics enhanced vascularization and osteogenesis through stimulating interactions between endothelia cells and bone marrow stromal cells. Biomaterials 2014, 35(12):3803-3818.\r
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Chengtie Wu, Pingping Han, Xiaoguo Liu, Mengchi Xu, Tian Tian, Jiang Chang*, Yin Xiao*. Mussel-inspired β-tricalcium phosphate bioceramics with Ca-P/polydopamine hybrid nanolayer: preparation, formation mechanism and improved cellular bioactivity. Acta Biomaterialia 2014, 10(1):428-438.\r
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Mengchi Xu, Dong Zhai, Jiang Chang*, Chengtie Wu*. In vitro assessment of 3D-Plotted nagelschmidtite bioceramic scaffolds with varied macropore morphology. Acta Biomaterialia 2014, 10(1):463-476.\r
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Chengtie Wu, Yinghong Zhou, Mengchi Xu, Pingping Han, Lei Chen, Jiang Chang*, Yin Xiao*. Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity. Biomaterials 2013, 34(2):422-433. \r
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Chengtie Wu*, Wei Fan, Jiang Chang*. Functional mesoporous bioactive glass nanospheres: synthesis, apatite mineralization, controllable delivery of doxorubicin and inhibitory effect on bone cancer cells. Journal of Materials Chemistry B 2013, 1(21): 2710-2718. (Cover paper)\r
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Chengtie Wu, Pingping Han, Mengchi Xu, Xufang Zhang, Yinghong Zhou, Guangda Xue, Jiang Chang*, Yin Xiao*. Nagelschmidtite bioceramics with osteostimulation property: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells. Journal of Materials Chemistry B 2013, 1(6):876-885.\r
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Chengtie Wu*, Minghui Zhang, Dong Zhai, Jianding Yu, Yan Liu, Huiying Zhu, Jiang Chang*. Containerless processing for preparation of akermanite bioceramic spheres with homogenous structure, tailored bioactivity and degradation. Journal of Materials Chemistry B. 2013, 1(7):1019-1026. \r
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Chen Wang, Kaili Lin, Jiang Chang*, Jiao Sun*. Osteogenesis and angiogenesis induced by porous b-CaSiO3/PDLGA compositescaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways. Biomaterials .2013, 34(1):64-77.\r
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Haiyan Li, Jiang Chang*. Stimulation of proangiogenesis by calcium silicate bioactive ceramic. Acta Biomaterilia. 2013; 9(2):5379-89.\r
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He Xu, Haiyan Li*, Jiang Chang*. Controlled drug release from polymer matrix by patterned electrospun nanofibers with controllable hydrophobicity. Journal of Materials Chemistry B 2013, 1(33): 4182-4188.\r
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Wanyin Zhai, Hongxu Lu, Chengtie Wu, Lei Chen, Xiaoting Lin, Kawazoe Naoki, Guoping Chen*, Jiang Chang*. Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro. Acta Biomaterialia 2013, 9(8): 8004-8014.\r
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Haiyan Li, Jiang Chang*. Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect. Acta Biomaterialia 2013, 9(6):6981-6991.\r
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Kaili Lin, Lunguo Xia, Jinbo Gan, Zhiyuan Zhang, Hong Chen*, Xinquan Jiang*, Jiang Chang*. Tailoring the Nanostructured Surfaces of Hydroxya patite Bioceramics to Promote Protein Adsorption, Osteoblast Growth, and Osteogenic Differentiation. ACS Applied Materials& Interfaces 2013, 5:8008-8017.\r
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Kaili Lin, Lunguo Xia,Haiyan Li, Xinquan Jiang,Haobo Pan,Yuanjin Xu,William W Lu, Zhiyuan Zhang*, Jiang Chang*. Enhanced osteoporotic bone regeneration by strontium-substituted calcium silicate bioactive ceramics. Biomaterials 2013, 34 (38): 10028-42. \r
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Chengtie Wu, Yinghong Zhou, Jiang Chang*, Yin Xiao*. Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells. Acta Biomaterialia 2013, 9(11):9159-9168.\r
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Yan Han, Qiongyu Zeng, Haiyan Li*, Jiang Chang*. The calcium silicate/alginate composite: preparation and evaluation of its behavior as bioactive injectable hydrogels. Acta Biomaterialia 2013, 9: 9107-9117.\r
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Lunguo Xia, Kaili Lin, Xinquan Jiang, Yuanjin Xu, Maolin Zhang, Jiang Chang*, Zhiyuan Zhang*. Enhanced osteogenesis through nano-structured surface design of macroporous hydroxyapatite bioceramic scaffolds via activation of ERK and p38 MAPK signaling pathways. Journal of Materials Chemistry 2013, 1:5403-5416.\r
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Chengtie Wu, Jiang Chang*, Wei Fan*. Bioactive mesoporous calcium-silicate nanoparticles with excellent mineralization ability, osteostimulation, drug-delivery and antibacterial properties for filling apex root of tooth. Journal of Materials Chemistry 2012, 22:16801-16809.\r
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Chengtie Wu, Yinghong Zhou, Chucheng Lin, Jiang Chang*, Yin Xiao*. Strontium-containing mesoporous bioactive glass scaffolds with improved osteogenic/cementogenic differentiation of periodontal ligament cells for periodontal tissue engineering. Acta Biomaterialia 2012, 8:3805-3815.