慈维敏
近期热点
资料介绍
个人简历
招生方向肿瘤表观基因组学生物信息学表观遗传学教育背景1999-09--2004-07 中科院生物物理研究所 博士1995-09--1999-07 北京师范大学 学士工作简历2014-01~2014-06,中国科学院北京基因组研究所, 研究员2009-08~2013-12,中国科学院北京基因组研究所, 副研究员2008-03~2009-08,Weill Cornell Medicine College, 博士后2004-10~2008-03,Albert Einstein College of Medicine, 博士后教授课程表观遗传学精准医学概论组学当代话题Omics表观基因组学人类基因组学研究-进展与应用生物适应和基因组变异基因组学专利成果( 1 ) 一种石蜡DNA提纯方法及其在基因组学中的应用, 发明, 2019, 第 2 作者, 专利号: 201510818823.X( 2 ) 维生素C衍生物在制备抗肿瘤产品中的应用, 发明, 2019, 第 1 作者, 专利号: 201710141994.2( 3 ) 一种cfDNA分类方法、装置和用途,慈维敏, 实用新型, 2019, 第 1 作者, 专利号: 201910374094.1( 4 ) 一种尿沉渣基因组DNA的分类方法、装置和用途, 实用新型, 2019, 第 1 作者, 专利号: 201911088433.6科研项目( 1 ) 生命科学领域优秀青年科技专项, 主持, 部委级, 2011-01--2013-12( 2 ) 自然科学基金面上项目, 主持, 国家级, 2012-01--2015-12( 3 ) 肿瘤转移过程中基因突变和表观遗传变异协同性进化的规律, 主持, 国家级, 2013-05--2015-12( 4 ) DNA甲基化/去甲基化重编程在泌尿系统上皮细胞分化、恶性转化、侵袭转移中的作用机理研究, 主持, 国家级, 2016-01--2016-12( 5 ) 肿瘤表观基因组学, 主持, 国家级, 2015-01--2017-12( 6 ) 肿瘤转移模式和表观遗传驱动力的识别, 主持, 部委级, 2016-08--2020-12( 7 ) 中国女性患者上尿路上皮癌复发的多基因机制研究, 主持, 国家级, 2017-01--2020-12( 8 ) 表观基因组学检测技术研发与临床应用, 参与, 国家级, 2016-07--2018-12( 9 ) 恶性肿瘤的基因组演化和精准医学研究, 参与, 部委级, 2016-01--2018-12( 10 ) 王宽诚率先人才计划“卢嘉锡国际团队项目”, 主持, 部委级, 2018-01--2020-12( 11 ) 器官再生机制及调控研究, 主持, 部委级, 2017-12--2022-12( 12 ) 增龄相关健康减损的生物学标志物研究, 主持, 国家级, 2018-12--2022-12参与会议(1)Large scale genomic aberrations characterize metastatic renal cell carcinoma evolution 2018-11-01(2)人类衰老干细胞m6A表观转录组重编程图谱和生物学功能 衰老生物学分会成立大会 2018-09-12(3)尿路上皮癌的基因组特征及潜在治疗靶点 2018全国微创泌尿外科年会(18th) 2018-05-12(4)SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer Guoqiang Li#, Weimin Ci#, Subhradip Karmakar#, Ke Chen, Zhixiang Fan, Zhongqiang Guo, Jing Zhang, Lu Wang, Min Zhuang, Shengdi Hu, Xuesong Li, Xianghong Li, Erin E. Mowers, Matthew F. Calabrese, Edmond R. Watson, Sandip Prasad, Carrie Rinker-Schaeffer, Scott E. Eggener, Thomas Stricker, Yong Tian, Brenda Schulman, 2015-11-10(5)A “survival of the Fittest” mechanism for weeding out potentially lymphomagenic B-cells during germinal center B-cell differentiation 第49界美国血液学年会 Ci, W. Polo, J.M. Ranuncolo, S.M. Melnick, A. 2007-12-08研究领域
"基因组学"近期论文
(1) Noninvasive Detection and Localization of Genitourinary Cancers Using Urinary Sediment DNA Methylomes and Copy Number Profiles, European Urology, 2019-11, 通讯作者(2) Detection of urothelial carcinoma based on copy number profiles of urinary cell-free DNA using shallow whole-genome sequencing, Clinical Chemistry, 2019-11, 通讯作者(3) Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer, Clinical Epigenetics, 2018, 通讯作者(4) Diagnostic and prognostic biomarkers of common urological cancers based on aberrant DNA methylation, Epigenomics, 2018, 通讯作者(5) Restoration of 5-hydroxymethylcytosine by ascorbate blocks kidney tumour growth, EMBO Reports, 2018, 通讯作者(6) Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer, Clinical Epigenetics, 2018, 通讯作者(7) Diagnostic and prognostic biomarkers of common urological cancers based on aberrant DNA methylation, Epigenomics, 2018, 通讯作者(8) Mouse Olfactory Bulb Methylome and Hydroxymethylome Maps Reveal Noncanonical Active Turnover of DNA Methylation, Epigenetics, 2017, 通讯作者(9) BCL6 antagonizes NOTCH2 to maintain survival of human follicular lymphoma cells, Cancer Discovery, 2017, 通讯作者(10) Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer, Cell research, 2016, 通讯作者(11) programming and inheritance of parental dna methylomes in vertebrates, Physiology, 2015, 第 1 作者(12) SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer, Cancer Cell, 2014, 第 2 作者(13) Sperm, but Not Oocyte, DNA Methylome Is Inherited by Zebrafish Early Embryos, Cell, 2013, 通讯作者(14) The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL, blood, 2009, 第 1 作者(15) Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells, blood, 2008, 第 2 作者(16) B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma, Curr Opin Hematol, 2008, 第 1 作者(17) Intracellular Ca2+ regulates the cellular iron uptake in K562 cells, cell calcium, 2003, 第 1 作者 相关热点
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