个人简历

李云琦，性别：男，1980年出生，籍贯：四川，毕业于中国科学院长春应用化学研究所，获得博士学位，教授/研究员/博士生导师，从事高性能材料基础的多学科交叉研究工作。
主要学习工作经历：
1997.9～2001.7 南京大学化学系，理学学士
2001.9～2007.3 中科院长春应化所高分子化学与物理重点实验室，理学博士
2005.5～2006.5 Rutgers大学食品系，交换学生
2007.5～2009.1 Kansas大学分子生物中心，博士后
2009.2～2010.5 Kansas大学应用生物信息实验室，博士后
2010.6～2012.11 Rutgers大学食品系，博士后
2013.1～至今 中科院长春应化所，研究员，博士生导师
     在化学和高分子物理化学学习研究经历的基础上，对分子生物学、生物信息学、蛋白质和食品科学以及高分子复合物等多个领域具有深入研究，阐述了一系列复杂体系的基本物理问题，开发了软件/服务器促进相关领域的深入研究。在以相互作用、分子构象、微结构、聚集和相行为、宏观性质的多个尺度相互联系为主线，拓展了基础物理理论模型在大分子复杂体系的应用，整合了一套对复杂体系行之有效的理论、模拟与实验相结合的多学科交叉研究方法。迄今，已发布了开源软件/服务器6个，在J. Phys. Chem. B, J. Chem. Phys.，Bioinformatics, BMC Bioinformatics, PLoS One，Proteins，Carbohydr. Polym.和Food Hydrocolloids等SCI核心期刊共发表论文30余篇，它引200余次，获得一项美国授权专利。

研究领域

在化学和高分子物理化学学习研究经历的基础上，对分子生物学、生物信息学、蛋白质和食品科学以及高分子复合物等多个领域具有深入研究"主要承担项目：
中科院长春应用化学研究所启动基金，自然科学基金"

近期论文

1. Xia S, Li Y, Xia Q, Zhang X, & Huang Q Glycosylation of bovine serum albumin via Maillard reaction prevents epigallocatechin-3-gallate-induced protein aggregation. Food Hydrocolloids 2015, 43(0):228-235.
2. Li Y, Zhao Q, & Huang Q Understanding complex coacervation in serum albumin and pectin mixtures using a combination of the Boltzmann equation and Monte Carlo simulation. Carbohydr. Polym. 2014, 101(0):544-553.
3. Li Y, An L, & Huang Q Replica Exchange Monte Carlo Simulation of Human Serum Albumin–Catechin Complexes. J. Phys. Chem. B 2014, 118(35):10362-10372.
4. Duan XZ, Zhang R, Li YQ, Yang YB, Shi TF, An LJ, & Huang QR Effect of polyelectrolyte adsorption on lateral distribution and dynamics of anionic lipids: a Monte Carlo study of a coarse-grain model. Eur Biophys J Biophy 2014, 43(8-9):377-391.
5. Duan XZ, Li YQ, Zhang R, Shi TF, An LJ, & Huang QR Compositional redistribution and dynamic heterogeneity in mixed lipid membrane induced by polyelectrolyte adsorption: Effects of chain rigidity. Eur Phys J E 2014, 37(8):71.
6. Li Y & Huang Q Influence of Protein Self-Association on Complex Coacervation with Polysaccharide: A Monte Carlo Study. J. Phys. Chem. B 2013, 117(9):2615-2624.
7. Li J, Li Y, Lee T-C, & Huang Q Structure and Physical Properties of Zein/Pluronic F127 Composite Films. J. Agric. Food Chem. 2013, 61(6):1309-1318.
8. Duan X, Zhang R, Li Y, Shi T, An L, & Huang Q Monte Carlo Study of Polyelectrolyte Adsorption on Mixed Lipid Membrane. J. Phys. Chem. B 2013, 117(4):989-1002.
9. Duan X, Li Y, Zhang R, Shi T, An L, & Huang Q Regulation of anionic lipids in binary membrane upon the adsorption of polyelectrolyte: A Monte Carlo simulation. AIP Adv. 2013, 3:062128.
10. Duan X, Li Y, Shi T, Huang Q, & An L Mutation induced structural variation in membrane proteins: Small but hard to catch. Chemical Research in Chinese Universities 2013, 29(5):1016-1021.
11. Li Y, Zhang J, Tai D, Russell Middaugh C, Zhang Y, & Fang J Prots: A fragment based protein thermo-stability potential. Proteins: Structure, Function, and Bioinformatics 2012, 80(1):81-92.
12. Li Y, Shi T, An L, & Huang Q Monte Carlo Simulation on Complex Formation of Proteins and Polysaccharides. J. Phys. Chem. B 2012, 116(10):3045-3053.
13. Li Y, Li J, Xia Q, Zhang B, Wang Q, & Huang Q Understanding the Dissolution of α-Zein in Aqueous Ethanol and Acetic Acid Solutions. J. Phys. Chem. B 2012, 116(39):12057-12064.
14. Li Y & Fang J PROTS-RF: A Robust Model for Predicting Mutation-Induced Protein Stability Changes. PLoS One 2012, 7(10):e47247.
15. Li Y, Xia Q, Shi K, & Huang Q Scaling Behaviors of α-Zein in Acetic Acid Solutions. J. Phys. Chem. B 2011, 115(32):9695-9702.
16. Li Y, Fang Y, & Fang J Predicting residue-residue contacts using random forest models. Bioinformatics 2011, 27(24):3379-3384.
17. Li Y, Middaugh CR, & Fang J A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants. BMC Bioinformatics 2010, 11(1):62.
18. Li Y & Fang J Distance-dependent statistical potentials for discriminating thermophilic and mesophilic proteins. Biochem. Biophys. Res. Commun. 2010, 396(3):736-741.
19. Li Y & Zhang Y REMO: A new protocol to refine full atomic protein models from C-alpha traces by optimizing hydrogen-bonding networks. Proteins: Structure, Function, and Bioinformatics 2009, 76(3):665-676.
20. Li Y, Roy A, & Zhang Y HAAD: A Quick Algorithm for Accurate Prediction of Hydrogen Atoms in Protein Structures. PLoS One 2009, 4(8):e6701.
21. Song J, Shi T, Li Y, Chen J, & An L Rigidity effect on phase behavior of symmetric ABA triblock copolymers: A Monte Carlo simulation. J. Chem. Phys. 2008, 129(5):054906.
22. Li Y, Lee J, Lal J, An L, & Huang Q Effects of pH on the Interactions and Conformation of Bovine Serum Albumin: Comparison between Chemical Force Microscopy and Small-Angle Neutron Scattering. J. Phys. Chem. B 2008, 112(12):3797-3806.
23. Wang X, Li Y, Wang YW, Lal J, & Huang Q Microstructure of beta-lactoglobulin/pectin coacervates studied by small-angle neutron scattering. J. Phys. Chem. B 2007, 111(3):515-520.
24. Song J, Li Y, Huang Q, Shi T, & An L Monte Carlo simulation on symmetric ABA/AB copolymer blends in confined thin films. J. Chem. Phys. 2007, 127(9):094903.
25. Li Y, Shi T, An L, Lee J, Wang X, & Huang Q Effects of polar group saturation on physical gelation of amphiphilic polymer solutions. J. Phys. Chem. B 2007, 111(42):12081-12087.
26. Li Y, Shi T, Sun Z, An L, & Huang Q Investigation of sol-gel transition in pluronic F127/D2O solutions using a combination of small-angle neutron scattering and Monte Carlo simulation. J. Phys. Chem. B 2006, 110(51):26424-26429.
27. Li Y, Huang Q, Shi T, & An L How does solvent molecular size affect the microscopic structure in polymer solutions? J. Chem. Phys. 2006, 125(4):044902.
28. Li Y, Huang Q, Shi T, & An L Effects of chain flexibility on polymer conformation in dilute solution studied by lattice Monte Carlo simulation. J. Phys. Chem. B 2006, 110(46):23502-23506.
29. Liao Y, Su Z, Ye X, Li Y, You J, Shi T, & An L Kinetics of Surface Phase Separation for PMMA/SAN Thin Films Studied by in Situ Atomic Force Microscopy. Macromolecules 2005, 38(2):211-215.
30. Li Y, Sun Z, Su Z, Shi T, & An L The effect of solvent size on physical gelation in triblock copolymer solutions. J. Chem. Phys. 2005, 122(19):194909.
31. Li Y, Sun Z, Shi T, & An L Conformation studies on sol-gel transition in triblock copolymer solutions. J. Chem. Phys. 2004, 121(2):1133-1140.