个人简历

主要学习、工作、出国经历
2002.09-2006.07安徽医科大学生物技术4年学士
2006.09-2012.06中国科学技术大学遗传学6年（硕博连读）博士
2012.07-2017.12安徽省立医院生殖中心助理研究员
2017.12-至今安徽省立医院生殖中心副研究员
2017.12-2018.03意大利锡耶纳大学医院生殖中心进修

研究领域

1. 多囊卵巢综合征（PCOS）发生和发展过程中microRNA的功能研究
2. 女性生殖相关疾病（PCOS等）的致病基因或关键位点的遗传筛查及功能研究
3. 生物信息学（网络工具与数据库构建等）在生殖生物学和遗传学中的应用"目前正在承担的科研项目(仅限于主要负责人)
项目名称、来源、经费指标卡号 总经费(万元) 起止日期
主持：miR-483-5p通过ERK1/2-MAPK通路调控颗粒细胞增殖-凋亡平衡及PCOS发生的机制研究(主持，国家自然科学基金，项目批号：81601244）
主持：miR-483-5p通过下游ERK1-MAPK通路调节颗粒细胞增殖-凋亡平衡及参与多囊卵巢综合征发生（主持，安徽省自然科学基金面上项目，项目批号：1708085MH183）
主持：安徽省立医院第三批“百名青年技术骨”培养计划 财政拨款17.5万
医院配套17.5万
财政拨款8万
医院配套8万
15万 2017.1-2019.12
2017.7-2019.9
2015.8-2018.8"

近期论文

(1) Xu B (First author & corresponding author),Zhang YW ,Zheng SX ,Tong XH, Liu YS, Expression Profile of MicroRNAs and Their Targeted Pathways in Human Ovaries Detected by Next-Generation Small RNA Sequencing, DNA Cell Biol. 2016 May;35(5):226-34.
(2) Zhang Y* ,Zang Q*, Xu B* (Co-First author) ,Zheng W, Ban R, Zhang H, Yang Y, Hao Q, Iqbal F, Li A, Shi Q, IsomiR Bank: a research resource for tracking IsomiRs, Bioinformatics. 2016 Jul 1;32(13):2069-71.
(3) Xu B (First author& corresponding author), Guo N, Zhang XM, Shi W, Tong XH, Iqbal F, Liu YS , Oocyte quality is decreased in women with minimal or mild endometriosis., Scientific Reports,2015,5：10799.
(4) Xu B (First author& corresponding author), Zhang YW ,Tong XH, Liu YS, Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS.,Mol Cell Endocrinol,2015,404(c)：26-36.
(5) Hua J*, Xu B* (Co-First author),Yang Y,Ban R,Iqbal F,Cooke HJ,Zhang Y ,Shi Q,Follicle Online: an integrated database of follicle assembly, development and ovulation.,Database,2015,bav036：1-8.
(6) Jia L*, Xu B* (Co-First author & corresponding author),Liu YS, Tong XH , Cryotop Vitrification Affects Oocyte Quality and Embryo Developmental Potential, EC Gynaecology,2015,1.2：46-52.
(7) Shi W* , Xu B* (Co-First author & corresponding author),Wu LM,Jin RT, Luan HB,Luo LH,Zhu Q,Johansson L,Liu YS,Tong XH,Oocytes with a dark zona pellucida demonstrate lower fertilization, implantation and clinical pregnancy rates in IVF/ICSI cycles.,PLoS ONE,2014,9(2)：e89409.
(8) Tong XH*, Xu B* (Co-First author & corresponding author), Zhang YW, Liu YS,Ma CH, Research resources: comparative microRNA profiles in human corona radiata cells and cumulus oophorus cells detected by next-generation small RNA sequencing.,PLoS One,2014,9(9)：e106706.
(9) Zhong L*,Zhang Y*, Xu B* (Co-First author),Yang Y,Ban R,Zhu J,Cooke HJ,Hao Q,Shi
Q, SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining.,Nucleic Acids Res,2013,41(Database issue)：1055-1062.
(10) Zhang Y* , Xu B* (Co-First author),Yang Y,Ban R,Zhang H,Jiang X,Cooke HJ,Xue Y,Shi Q,CPSS: a computational platform for the analysis of small RNA deep sequencing data.,Bioinformatics,2012,28(14)：1925-1927.
海峡两岸医药卫生交流协会遗传与生殖专委会青年委员
安徽中西医学会妇产科分委会青年委员