个人简历

田华雨，男，研究员，博士生导师，国家杰出青年基金获得者。中国科学院长春应用化学研究所生态环境高分子材料重点实验室生物医用高分子课题组工作。曾在韩国KAIST、日本九州大学做客座研究，在美国犹他大学做访问学者。目前主要从事生物医用高分子、纳米基因/药物载体、基因治疗、免疫治疗、肿瘤疫苗等方面的研究。在JACS、Angew、AM、AFM、ACS Nano、Nano Lett等国际主流杂志发表SCI论文150余篇。获权中国发明专利25项。2007和2011年获得吉林省科技进步一等奖，2012年获得国家自然科学基金优秀青年基金资助，入选2014年度中组部“万人计划”青年拔尖人才。所开发的细胞用基因转染试剂实现产业化。
教育经历:
1994-1998，哈尔滨工业大学，高分子材料专业，本科
1998-2000，哈尔滨工业大学，高分子材料专业，硕士
2002-2005，中科院长春应用化学研究所，高分子化学专业，博士
工作经历:
2006-2008，中科院长春应用化学研究所，助理研究员
2007.6-7，韩国科学技术院（KAIST），客座研究
2008.8，日本九州大学，客座研究
2008-2012，中科院长春应用化学研究所，副研究员
2009-2010，美国犹他大学，访问学者
2012-现在，中科院长春应用化学研究所，研究员

研究领域

""生物医用高分子、纳米基因/药物载体、基因治疗、免疫治疗、肿瘤疫苗""""

近期论文

[1]Liu, F.; Lin, L.; Zhang, Y.; Wang, Y.; Sheng, S.; Xu, C.; Tian, H.*; Chen, X.*, A Tumor-Microenvironment-Activated Nanozyme-Mediated Theranostic Nanoreactor for Imaging-Guided Combined Tumor Therapy, Advanced Materials, 2019, 31, 1902885.
[2]Liu, F.; Lin, L.; Zhang, Y.; Sheng, S.; Wang, Y.; Xu, C.; Tian, H.*; Chen, X., Two-dimensional nanosheets with high curcumin loading content for multimodal imaging-guided combined chemo-photothermal therapy, Biomaterials, 2019, 223, 119470.
[3]Wang, D.; Zhang, Z.; Lin, L.; Liu, F.; Wang, Y.; Guo, Z.; Li, Y.; Tian, H.*; Chen, X., Porphyrin-based covalent organic framework nanoparticles for photoacoustic imaging-guided photodynamic and photothermal combination cancer therapy, Biomaterials, 2019, 223, 119459.
[4]Zhang, Y.; Lin, L.; Liu, L.; Liu, F.; Sheng, S.; Tian, H.*; Chen, X., Positive feedback nanoamplifier responded to tumor microenvironments for self-enhanced tumor imaging and therapy. Biomaterials, 2019, 216, 119255.
[5]Wang, K.; Zhang, Z.; Lin, L.; Chen, J.; Hao, K.; Tian, H.*; Chen, X., Covalent organic nanosheets integrated heterojunction with two strategies to overcome hypoxic-tumor photodynamic therapy. Chemistry of Materials, 2019, 31 (9), 3313-3323.
[6]Wang, Y.; Wang, Z.; Xu, C.*; Tian, H.*; Chen, X., A disassembling strategy overcomes the EPR effect and renal clearance dilemma of the multifunctional theranostic nanoparticles for cancer therapy. Biomaterials, 2019, 197, 284-293.
[7]Fang, H.; Guo, Z.; Lin, L.; Chen, J.; Sun, P.; Wu, J.; Xu, C.; Tian, H.*; Chen, X.*, Molecular strings significantly improved the gene transfection efficiency of polycations. Journal of the American Chemical Society, 2018, 140 (38), 11992-12000.
[8]Zhen, W.; Liu, Y.; Lin, L.; Bai, J.; Jia, X.; Tian, H.*; Jiang, X.*, BSA-IrO2: catalase-like nanoparticles with high photothermal conversion efficiency and a high X-ray absorption coefficient for anti-inflammation and antitumor theranostics. Angewandte Chemie International Edition, 2018, 57 (32), 10309-10313.
[9]Xu, C.; Wang, Y.; Yu, H.; Tian, H.*; Chen, X.*, Multifunctional theranostic nanoparticles derived from fruit-extracted anthocyanins with dynamic disassembly and elimination abilities. ACS Nano, 2018, 12 (8), 8255-8265.
[10]Yan, N.; Wang, X.; Lin, L.; Song, T.; Sun, P.; Tian, H.*; Liang, H.*; Chen, X.*, Gold nanorods electrostatically binding nucleic acid probe for in vivo microRNA amplified detection and photoacoustic imaging-guided photothermal therapy. Advanced Functional Materials, 2018, 28 (22), 1800490.
[11]Guan, X.; Chen, J.; Hu, Y.; Lin, L.; Sun, P.; Tian, H.*; Chen, X., Highly enhanced cancer immunotherapy by combining nanovaccine with hyaluronidase. Biomaterials, 2018, 171, 198-206.
[12]Guan, X.; Guo, Z.; Lin, L.; Chen, J.; Tian, H.*; Chen, X.*, Ultrasensitive pH triggered charge/size dual-rebound gene delivery system. Nano Letters, 2016, 16 (11), 6823-6831.
[13]Xu, C.; Wang, P.; Zhang, J.; Tian, H.*; Park, K.; Chen, X.*, Pulmonary codelivery of doxorubicin and siRNA by pH-sensitive nanoparticles for therapy of metastatic lung cancer. Small, 2015, 11 (34), 4321-4333.