个人简历

主要学习、工作、出国经历
2001.9-2005.7安徽大学生物化学学士
2005.9-2011.7中国科学技术大学遗传学博士

研究领域

1．非编码RNA基因调控膀胱癌化疗耐受性的机制研究
2．受DNA甲基化调控的基因调控食管鳞癌细胞放疗敏感性的机制研究"目前正在承担的科研项目(仅限于主要负责人)
项目名称、来源、经费指标卡号 总经费(万元) 起止日期
DNA甲基化调控的miR-193a基因转录调控机制与膀胱癌化疗耐受、国自然青年基金、81602230 财政拨款17万
医院配套17万 2017.1-2019.12"

近期论文

1.Lv, L., et al. (2014). The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression. Cell Death Dis5: e1402. （first author）
2.Lv, L., et al. (2015). MiR-193a-3p promotes the multi-chemoresistance of bladder cancer by targeting the HOXC9 gene. Cancer Lett357(1): 105-113. （first author）
3.Deng, H., et al. (2014). miR-193a-3p regulates the multi-drug resistance of bladder cancer by targeting the LOXL4 gene and the oxidative stress pathway. Mol Cancer13: 234. (co-first author)
4.Deng, H., et al. (2015). The miR-193a-3p regulated PSEN1 gene suppresses the multi-chemoresistance of blad-der cancer. Biochim Biophys Acta1852(3): 520-528. (co-first author)
5.Li, Y., et al. (2015). The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and
inhibits multi-chemoresistance in bladder cancer. Oncotarget6(12): 10195-10206. (co-first author)