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洪泂
2023-05-16 13:12
  • 洪泂
  • 洪泂 - 副教授-中国科学技术大学-合肥微尺度物质科学国家研究中心-个人资料

近期热点

资料介绍

个人简历


教育与科研经历
2008.4 - 现在 中国科学技术大学生命科学学院
2006.8 - 2008.2 美国弗吉尼亚理工大学,博士后
2003.11 - 2006.8 日本京都大学,博士后
1999.10 - 2003.2 日本京都大学, 博士
1996.7 - 2003.10 北京师范大学,助教/讲师
1993.9 - 1996.7 北京师范大学,硕士
1989.9 - 1993.7 安徽师范大学,本科

研究领域


1. 以耐热酵母为平台构建利用木质纤维素生物质的微生物细胞工厂。通过合成生物学手段对耐热的马克斯克鲁维酵母进行改造,实现利用秸秆、玉米芯等材料进行乙醇、木糖醇、乳酸等产品的生产。
2. 高通量DNA合成技术。高通量DNA合成技术是合成生物学中重要的使能技术,目前研究专注于研发高效去除合成过程中错误的技术。""

近期论文


1. Hua Yan, Wang Jichao, Zhu Yelin, Zhang Biao, Kong Xin, Li Wenjie, Wang Dongmei, Hong Jiong*, (2019). Release of glucose repression on xylose utilization in Kluyveromyces marxianus to enhance glucose-xylose co-utilization and xylitol production from corncob hydrolysate. Microbial Cell Factories. 18:24.
2. Kong Xin, Zhang Biao, Hua Yan, Zhu Yelin, Li Wenjie, Wang Dongmei, Hong Jiong*, (2019). Efficient L-lactic acid production from corncob residue using metabolically engineered thermo-tolerant yeast. Bioresource Technology. 273, p220-230.
3. Zhang Biao, Zhu Yelin, Zhang Jia, Wang Dongmei, Sun Lianhong, Hong Jiong* , (2017). Engineered Kluyveromyces marxianus for pyruvate production at elevated temperature with simultaneous consumption of xylose and glucose. Bioresoure Technology, 224, 553-562.
4. Zhang Biao, Zhang Jia, Wang Dongmei, Han Ruixiang., Ding Rui, Gao Xiaolian., Sun Lianhong, Hong Jiong*, (2016). Simultaneous fermentation of glucose and xylose at elevated temperatures co-produces ethanol and xylitol through overexpression of a xylose-specific transporter in engineered Kluyveromyces marxianus. Bioresource Technology, 216, 227-237. (Best article in this issue)
5. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Sun Lianhong and Hong Jiong*, (2015). Rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase-xylitol dehydrogenase pathway. Metabolic Engineering, 31, 140-152.
6. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian and Hong Jiong*, (2015). Improving xylitol production at elevated temperature with engineered Kluyveromyces marxianus through over-expressing transporters. Bioresource Technology 175: 642-645.
7. Wan, Wen; Li, Lulu; Xu, Qianqian; Wang, Zhefan; Yao, Yuan; Wang, Rongliang; Zhang, Jia; Liu, Haiyan; Gao, Xiaolian*; Hong, Jiong* (2014). Error removal in microchip-synthesized DNA using immobilized MutS. Nucleic Acids Research, 42(12), e102.
8. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Hong Jiong* (2014). Xylitol production at high temperature by engineered Kluyveromyces marxianus. Bioresource Technology 152:192-201.

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