个人简历

学习工作简历： 2015年12月至今：中国海洋大学 海洋生命学院 副教授 2014年4月—2015年11月： 中国海洋大学 海洋生命学院 讲师 2012年8月—2014年1月：国家纳米科学中心 联合培养 2008年9月—2013年6月：中国海洋大学 海洋生命学院 海洋生物学专业 博士 2004年9月—2008年6月：中国海洋大学 海洋生命学院 生物技术专业 学士

研究领域

海洋生物医用材料、纳米生物材料

近期论文

1. Ya Liu , Di Zhang , Zeng-Ying Qiao , Guo-Bin Qi , Xing-Jie Liang , Xi-Guang Chen*, Hao Wang*. A Peptide-Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy. Advanced Materials27 (2015) 5034–5042 (IF: 21.95) 2. Ya Liu, Li-Li Li, Guo-Bin Qi, Yun-Shan Fan, Xi-Guang Chen*, Hao Wang*. Dynamic Disordering of Co-Assemblied Liposomal Cocktails: Spatio-Temporal Controlled Release of Cargoes to Circumvent Drug Resistance. Biomaterials 35 (2014) 3406-3415. (IF: 8.806) 3. Ya Liu, Fu-Ping Gao, Di Zhang, Yun-Shan Fan, Xi-Guang Chen*, Hao Wang*. Molecular Structural Transformation Regulated Dynamic Disordering of Supramolecular Vesicles as pH-Responsive Drug Release Systems. Journal of Controlled Release 173 (2014) 140–147. (IF: 7.877) 4. Ya Liu, Xiguang Chen*, Hao Wang, Nanoplatform containing MMPs-sensitive peptide-PEG conjugate and tissue-penetrating moiety for enhanced cancer therapy. Journal of Controlled Release DOI: 10.1016/j.jconrel.2017.03.324.(IF: 7.877) 5.Ya Liu*, Fang-Qin Wang, Zeana Shah, Xiao-Jie Cheng, Ming Kong, Chao Feng, Xi-Guang Chen*. Nano-polyplex based on oleoyl-carboxymethy-chitosan (OCMCS) andhyaluronic acid for oral gene vaccine delivery. Colloids and Surfaces B: Biointerfaces145 (2016) 492–501. (IF: 3.997) 6. Ya Liu, Ming Kong, Xiao Jie Cheng, Qian Qian Wang, Li Ming Jiang, Xi Guang Chen*. Self-assembled nanoparticles based on amphiphilic chitosan derivative and hyaluronic acid for gene delivery. Carbohydrate Polymers 94 (2013) 309-316. (IF: 5.158) 7. Ya Liu, Ming Kong, Kui Kun Yang, Yang Li, Jing Su, Xiao Jie Cheng, Hyun Jin Park*, Xi Guang Chen*. Biocompatibility, cellular uptake and biodistribution of the polymeric amphiphilic nanoparticles as oral drug carriers. Colloids and Surfaces B: Biointerfaces 103 (2013) 345-353. (IF: 3.997) 8. Ya Liu, Hui Di Zang, Ming Kong, Fang Kui Ma, Qi Feng Dang, Xiao Jie Cheng*, Qiu Xia Ji, Xi Guang Chen*. In vitro evaluation of mucoadhesion and permeation enhancement of polymeric amphiphilic nanoparticles. Carbohydrate Polymers89 (2012) 453– 460. (IF: 5.158) 9. Ya Liu, Xiao Jie Cheng, Qi Feng Dang, Fang Kui Ma,Xi Guang Chen*, Hyun Jin Park, Bum Keun Kim. Preparation and evaluation of Oleoyl-carboxymethy-chitosan (OCMCS) nanoparticles as oral protein carriers. Journal of Material Science: Material in Medicine. 23(2012) 375–384. (IF: 2.448) 10. Mei-Ping Tian, Rui-Xi Song, Ting Wang, Meng-Jie Sun, Ya Liu*, Xi-Guang Chen*. Inducing sustained release and improving oral bioavailability of curcumin via chitosan derivatives-coated liposomes. International Journal of Biological Macromolecules. 120 (2018) 702–710. (IF: 3.909) 11. Zixian Bao, Changqing Jiang, Zhiguo Wang, Qiuxia Ji, Guohui Sun, Shichao Bia, Ya Liu*, Xiguang Chen*. The influence of solvent formulations on thermosensitive hydroxybutyl chitosan hydrogel as a potential delivery matrix for cell therapy. Carbohydrate Polymers170 (2017) 80–88. (IF: 5.158) 12. Guixue Xia, Ya Liu*, Meiping Tian, Ping Gao, Zixian Bao, Xiaoyu Bai, Xiaoping Yu, Xuqian Lang, Shihao Hu and Xiguang Chen*. Nanoparticles/thermosensitive hydrogel reinforced with chitin whiskers as a wound dressing for treating chronic wounds. Journal of Materials Chemistry B 5(2017) 3172—3185. (IF: 4.776) 13. Zixian Bao, Ping Gao, Guixue Xia, Zhiguo Wang, Ming Kong, Chao Feng, Xiaojie Cheng,* Ya Liu* and Xiguang Chen*. A thermosensitive hydroxybutyl chitosan hydrogel as a potential co-delivery matrix for drugs on keloid inhibition. Journal of Materials Chemistry B4(2016) 3936—3944. (IF: 4.776) 14. Ping Gao, Guixue Xia, Zixian Bao, Chao Feng, Xiaojie Cheng, Ming Kong, Ya Liu*, Xiguang Chen*. Chitosan based nanoparticles as protein carriers for efficient oral antigen delivery. International Journal of Biological Macromolecules 91 (2016) 716–723. (IF: 3.909) 15. Fangqin Wang, Guixue Xia, Xuqian Lang, Xuanxuan Wang, Zixian Bao, Zeenat Shah, Xiaojie Cheng, Ming Kong, Chao Feng, Ya Liu*, Xiguang Chen*. Influence of the graft density of hydrophobic groups on thermo-responsive nanoparticles for anti-cancer drugs delivery. Colloids and Surfaces B: Biointerfaces148 (2016) 147–156. (IF: 3.997) 16. Juan Wang, Ming Kong, Zhenjin Zhou, Dong Yan, Xiaoping Yu, Xiaojie Cheng, Chao Feng, Ya Liu*, Xiguang Chen*. Mechanism of surface charge triggered intestinal epithelial tight junction opening upon chitosan nanoparticles for insulin oral delivery. Carbohydrate Polymers157 (2017) 596–602. (IF: 5.158)