个人简历

中国海洋大学海洋生命学院教授，博士研究生导师，中共党员，毕业于中国海洋大学海洋生物系，任海洋生命学院海洋生物工程系主任

研究领域

实验室主要从事海洋生物材料的分子改性、功能活性及其在医学及健康领域的应用基础研究和产品开发研究，研究海洋生物医用材料、海洋生物活性物质、海洋生物酶及生化制品。

近期论文

1、Jiang Zhiwen, Chi Jinhua, Han Baoqin*, Liu Wanshun. Preparation and pharmacological evaluation of norcantharidin-conjugated carboxymethyl chitosan in mice bearing hepatocellular carcinoma.[J]. Carbohydrate Polymers, 2017, 174:282 2、Qiao Jing, JiangZhiwen, YangYan, Chi Jinhua, QiaoXuesong, Han Baoqin*, Liu Wanshun. Study of a new biodegradable hernia patch to repair abdominal wall defect in rats.[J]. Carbohydrate Polymers, 2017, 172:255 3、Qiao Jing, Jiang Zhiwen, Liang Xuyue, Yang Yan, Liu Wanshun, Han Baoqin*. Biomechanical properties and healing effects of chitin patch in a ratfull-thickness abdominal wall defect model.[J]. J Journal of Biomedical Materials Research Part B Applied Biomaterials, 2017:00B:000–000 4、Qiao Xuesong, Peng Xiaoting, QiaoJing, Jiang Zhiwen, Han Baoqin*, YangChaozhong, LiuWanshun. Evaluation of a photocrosslinkable hydroxyethyl chitosan hydrogel as a potential drug release system for glaucoma surgery.[J]. Journal of Materials Science Materials in Medicine, 2017, 28(10):149 5、Jiang Xiaolei, Yang Zhao, Peng Yanfei, Han Baoqin*, Li Zhuoyue, Li Xiuhua, Liu Wanshun. Preparation, characterization and feasibility study of dialdehyde carboxymethyl cellulose as a novel crosslinking reagent.[J]. Carbohydrate Polymers, 2016, 137:632 6、Zhiwen Jiang, Baoqin Han*, Hui Li, Xiuhua Li, Yan Yang, Wanshun Liu. Preparation and anti-tumor metastasis of Carboxymethyl chitosan Carbohydrate Polymers. Carbohydrate Polymers, 2015, 125: 53–60 7、Zhiwen Jiang; Baoqin Han*; Hui Li; Yan Yang; Wanshun Liu. Carboxymethyl chitosan represses tumor angiogenesis in vitro and in vivo. Carbohydrate Polymers, 2015, 129: 1–8 8、Shao Kai, Han Baoqin*, Gao Jinning, Song Fulai, Yang Yan, Liu Wanshun. Synthesis and Characterization of a Hydroxyethyl Derivative of Chitosan and Evaluation of Its Biosafety. J. Ocean Univ. China (Oceanic and Coastal Sea Research), 2015 14 (4): 703-709 9、Shao Kai, Han Baoqin*, Dong Wen, Song Fulai, Liu Weizhi, and Liu Wanshun. Pharmacokinetics and Biodegradation Performance of a Hydroxypropyl Chitosan Derivative. J. Ocean Univ. China, 2015 14 (5): 888-896. 10、Shao Kai, Han Baoqin*, Gao Jinning, Jiang Zhiwen, Liu Weizhi, Liu Wanshun, Liang Ye. Fabrication and feasibility study of an absorbable diacetyl chitin surgical suture for wound healing[J]. Journal of Biomedical Materials Research Part B Applied Biomaterials, 2015, 104(1):116-125 11、Qingqing Bi，Jinxin Chu，Yilin Feng，Zhongqing Jiang，Baoqin Han*，Wanshun Liu。Purification and Characterization of a New Serine Protease with Fibrinolytic Activity from the Marine Invertebrate，Urechis unicinctus。Appl Biochem Biotechnol，2013，170:525–540 12、Qingqing Bi，Baoqin Han*，Wanshun Liu，Yilin Feng，Zhongqing Jiang。UFEIII, a fibrinolytic protease from the marine invertebrate, Urechis unicinctus。Biotechnol Lett，2013，35:1115–1120 13、Wen Dong，Baoqin Han*，Kai Shao，Zhao Yang，Yanfei Peng，Yan Yang，Wanshun Liu。Effects of molecular weights on the absorption, distribution and urinary excretion of intraperitoneally administrated carboxymethyl chitosan in rats。Journal of Materials Science: Materials in Medicine，2012，23（12）：2945–2952 14、Zhao Yang，Baoqin Han*，Dawei Fu，Wanshun Liu。Acute toxicity of high dosage carboxymethyl chitosan and its effecton the blood parameters in rats。J Mater Sci: Mater Med ，2012，23（12）：457–462 15、Dawei Fu，Baoqin Han，Wen Dong，Zhao Yang，You Lv，Wanshun Liu。Effects of carboxymethyl chitosan on the blood system of rats。Biochemical and Biophysical Research Communications 408，2011，110–114 16、Meiling Zheng，Baoqin Han*，Yan Yang，Wanshun Liu。Synthesis, characterization and biological safety of O-carboxymethyl chitosan used to treat Sarcoma 180 tumor。Carbohydrate Polymers，2011，86：231–238 17、Minyu Li，Baoqin Han*，Wanshun Liu。Preparation and properties of a drug release membrane of mitomycin C with N-succinyl-hydroxyethyl chitosan。J Mater Sci: Mater Med，2011，22：2745–2755 18、Wen Dong， Baoqin Han*， Yilin Feng，Fulai Song，Jing Chang，Huiping Jiang，Yingying Tang，and Wanshun Liu。Pharmacokinetics and Biodegradation Mechanisms of a Versatile Carboxymethyl Derivative of Chitosan in Rats: In Vivo and In Vitro Evaluation。Biomacromolecules，2010，11：1527–1533 1527