个人简历

海洋生物多样性与进化研究所副所长

主要成果：
迄今在国际主流刊物发表论文40余篇，包括多篇发表在Genes & Development、Nucleic Acids Research等领域旗舰级刊物上。先后主持国家自然科学基金“优秀青年基金”、面上项目、国家“万人计划”青年拔尖人才项目、山东省“杰出青年基金”、山东省“泰山学者”青年专家计划等多项科研项目。获得2017年中国动物学会青年科技奖、2017年山东省青年科技奖、2015年中国动物学会原生动物学分会青年科技奖和2013年国际原生动物学家学会Holz-Conner Award。

研究领域

主要从事纤毛虫表观遗传学研究""

近期论文

1. Xiao Chen, Yurui Wang, Yalan Sheng, Alan Warren, Shan Gao* (2018). GPSit: An automated method for evolutionary analysis of nonculturable ciliated microeukaryotes. Molecular Ecology Resources, doi: 10.1111/1755-0998.12750 (2018-01-04 online) (IF=7.6，进化生物学二区). 2. Yuanyuan Wang, Xiao Chen, Yalan Sheng, Yifan Liu, Shan Gao* (2017). N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena. Nucleic Acids Research, 45, 11594-11606. doi:10.1093/nar/gkx883 (IF=10.18，生化与分子生物学二区). 3. Jan H. Suhren, Tomoko Noto, Kataoka Kensuke, Shan Gao, Yifan Liu, Kazufumi Mochizuki (2017). Negative regulators of an RNAi-heterochromatin positive feedback loop safeguard somatic genome integrity in Tetrahymena. Cell Reports, 18, 2494-2507(IF=8.3，细胞生物学二区). 4. Xiaolu Zhao, Yuanyuan Wang, Yurui Wang, Yifan Liu, Shan Gao* (2017). Histone methyltransferase TXR1 is required for both H3 and H3.3 lysine 27 methylation in the well-known ciliated protist Tetrahymena thermophila. Science China-Life Sciences中国科学, 60, 264-270. 5. Jie Xiong#, Shan Gao#, Wen Dui, Wentao Yang, Xiao Chen, Sean D. Taverna, Ronald E. Pearlman, Wendy Ashlock, Wei Miao and Yifan Liu (2016). Dissecting relative contribution of cis- and trans- determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin. Nucleic Acids Research, 44, 10091-10105. (IF=10.18，生化与分子生物学二区). 6. Jie Huang, Xiaotian Luo, William A. Bourland, Feng Gao*, Shan Gao* (2016). Multigene-based phylogeny of the ciliate families Amphisiellidae and Trachelostylidae (Protozoa: Ciliophora: Hypotrichia). Molecular Phylogenetics and Evolution, 101, 101-110 (IF=4.4，进化生物学二区). 7. Xiao Chen, Hongbo Pan, Jie Huang, Alan Warren, Saleh A. Al-Farraj, Shan Gao* (2016). New considerations on the phylogeny of cyrtophorian ciliates (Protozoa, Ciliophora): expanded sampling to understand their evolutionary relationships. Zoologica Scripta, 45, 334-348 (IF=3.0，动物学一区). 8.Shan Gao#, Ling Lu#, Yan Bai, Weibo Song, Cunming Duan (2014). Structural and functional analysis of amphioxus HIFα reveals ancient features of the HIFα family. FASEB Journal, 28, 1880-1890 (IF=5.5，生化与分子生物学二区). 9. Chunchao Zhang, Shan Gao, Yifan Liu, Philip C. Andrews (2014). Quantitative Proteomics Reveals Histone Modifications in Crosstalk with H3 Lysine 27 Methylation. Molecular & Cellular Proteomics, 13, 749-759 (IF=6.6，生化研究一区). 10.Shan Gao#, Jie Xiong#, Chunchao Zhang, Brian R. Berquist, Rendong Yang, Meng Zhao, Anthony J. Molascon, Shaina Y. Kwiatkowski, Dongxia Yuan, Zhaohui Qin, Jianfen Wen, Geoffrey M. Kapler, Philip C. Andrews, Wei Miao, Yifan Liu (2013). Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & Development, 27, 1662-1679. (IF=12.6，遗传学一区).