曾宪春
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曾宪春男博士、教授、博士生导师、生物地质与环境地质国家重点实验室研究员、国际杂志(FrontiersinBioscience)(IF:3.5)编委(ManagingEditor)、国家科技奖励评选办公室评审专家、湖北省生物物理学会常务理事、民建武汉市委委员。在武汉大学先后获得生物化学专业学士、分子生物学专业硕士、微生物学专业博士学位。2001-2008年先后赴德国马普免疫学研究所、美国国家卫生研究院和美国马里兰大学医学院从事研究工作;2009年在美国科贝尔国际公司任部门负责人。主要从事分子生物学、地质微生物学和环境基因组学领域的研究工作。近年来发表SCI期刊论文52篇,其中以第一作者或通讯作者发表41篇(第一作者22篇,通讯作者19篇),论文被引用近1100余次。2005年获湖北省自然科学一等奖,2008年获国际基因组先驱者奖(GenomicPioneerAwards)提名奖。研究工作经历·2010年至今中国地质大学(武汉)生物地质与环境地质国家重点实验室,博士生导师;·2008年—2009年美国ColbellInternationalInc.,部门负责人(ChiefScientist);·2005年—2008年美国UniversityofMarylandSchoolofMedicine,研究员(ResearchFellow);·2002年—2005年美国NationalInstitutesofHealth,研究科学家(ResearchScientist);·2001年—2002年德国Max-PlanckInstituteforImmunobiology,高级访问学者(AdvancedVisitingScientist);·1990年—2001年先后在武汉大学生物毒素中心、生命科学学院任助教、讲师、副教授。科研项目1.国家自然科学基金:微生物参与江汉平原高砷地下水形成的分子机制(No.41272257)(2015-2018)2.国家自然科学基金:大同盆地高砷沉积物中微生物砷氧化酶与还原酶基因的多样性及其活性调节的研究(No.41472219)(2013-2016)3.国家自然科学基金:基于环境基因组和转录组学的高砷地下水沉积物微生物群落的生物地球化学作用的研究(No.41072181)(2011-2013)4.国家重点基础研究发展计划(973)项目子课题:我国特有产毒动物多肽毒素的基础与应用基础研究(No.2010CB529800)(2010-2014)5.中央高校基本科研业务费课题:A蝎毒素活性多肽的基础和应用研究(No.CUGL110604)B蝎毒素转录组学和蛋白组学的研究(No.CUGL120608)4.生物地质与环境地质国家重点实验室自主开放基金:塔克拉玛干沙漠典型大气-植被-土壤-地下水系统中的氮的生物地球化学循环过程主要教学课程高级分子生物学(研究生课程)、细胞生物学(本科生课程)研究领域
地质与极端环境微生物介导的生物地球化学循环地质与环境微生物分子生物学研究有毒动物与环境的相互作用:蛋白质组、转录组与生物信息学研究毒素多肽药物开发与地质微生物酶的工业应用研究近期论文
(1)JianingWang,Xian-ChunZeng*,XianbinZhu,XiaomingChen,XinZeng,YaoMu,YeYangYanxinWang.Sulfateenhancesthedissimilatoryarsenate-respiringprokaryotes-mediatedmobilization,reductionandreleaseofinsolublearsenicandironfromthearsenic-richsedimentsintogroundwater.JournalofHazardousMaterials,2017,339:409-417.(IF:6.1)(2)YeYang,YaoMu,Xian-ChunZeng*,WeiweiWu,JieYuan,YichenLiu,EGuoji,FengLuo,XiaomingChen,HaoLi,JianingWang,Functionalgenesandthermophilicmicroorganismsresponsibleforarseniteoxidationfromtheshallowsedimentofanuntraversedhotspringoutlet,Ecotoxicology,2017,26(4):490-501.(IF:2.3)(3)LinghuaXu,WanxiaShi,Xian-ChunZeng*,YeYang,LingliZhou,YaoMu,YichenLiu,Draftgenomesequenceofarthrobactersp.strainb6isolatedfromthehigh-arsenicsedimentsindatongbasin,china.StandardsinGenomicSciences,2017,12(1):11.(IF:1.6)(4)JieZhong,Xian-ChunZeng*,XinZeng,YaoNie,LeiZhang,ShifenWu,AorigeleBao,TranscriptomicanalysisofthevenomglandsfromthescorpionHadogenestroglodytesrevealeduniqueandextremelyhighdiversityofthevenompeptides,JournalofProteomics,2017,150:40-62.(IF:3.9)(5)HaoLi,Xian-ChunZeng*,ZhongHe,XiaomingChen,GuojiE,YiyangHan,YanxinWang,Long-termperformanceofrapidoxidationofarseniteinsimulatedgroundwaterusingapopulationofarsenite-oxidizingmicroorganismsinabioreactor,WaterResearch,2016,101:393-401.(IF:6.9)(6)Xian-ChunZeng*,GuojiE,JianingWang,NianWang,XiaomingChen,YaoMu,HaoLi,YeYang,YichenLiu,YanxinWang,Functionsanduniquediversityofgenesandmicroorganismsinvolvedinarseniteoxidationfromthetailingsofarealgarmine.AppliedandEnvironmentalMicrobiology,2016,82(24):7019-7029.(IF:3.9)(7)XiaomingChen,Xian-ChunZeng*,JianingWang,YaminDeng,TengMa*,E.Guoji,YaoMu,YeYang,HaoLi,YanxinWang,MicrobialcommunitiesinvolvedinarsenicmobilizationandreleasefromthedeepsedimentsintogroundwaterinJianghanplain,CentralChina,ScienceoftheTotalEnvironment,2016,579:989-999.(IF:4.0)(8)YaoMu,LingliZhou,Xian-ChunZeng*,LanLiu,YunfanPan,XiaomingChen,JianingWang,ShanhuiLi,Wen-junLi,YanxinWang,Arsenicitaleaaurantiacagen.nov.,sp.nov.,anewmemberofthefamilyHyphomicrobiaceae,isolatedfromhigh-arsenicsediment,InternationalJournalofSystematicandEvolutionaryMicrobiology,2016,66(12):5478-5484.(IF:2.4)(9)YaoMu,YunfanPan,WanxiaShi,LanLiu,ZhaoJiang,XuesongLuo,Xian-ChunZeng*,Wen-JunLi.Luteimonasarsenicasp.nov.,anarsenic-tolerantbacteriumisolatedfromarsenic-contaminatedsoil.InternationalJournalofSystematicandEvolutionaryMicrobiology,2016,66(6):2291-2296.(IF:2.4)(10)LeiZhang,WanxiaShi,Xian-ChunZeng*,FengGe,MingkunYang,YaoNie,AorigeleBao,ShifenWu,GuojiE,UniquediversityofthevenompeptidesfromthescorpionAndroctonusbicolorrevealedbytranscriptomicandproteomicanalysis,JournalofProteomics,2015,128:231-250.(IF:3.9)(11)AorigeleBao,JieZhong,Xian-ChunZeng*,YaoNie,LeiZhang,ZhaoFengPeng,Anovelcysteine-freevenompeptidewithstrongantimicrobialactivityagainstantibiotics-resistantpathogensfromthescorpionOpistophthalmusglabrifrons,JournalofPeptideScience,2015,21(10):758-764.(IF:2.0)(12)Xian-ChunZeng*,YichenLiu,WanxiaShi,LeiZhang,XuesongLuo,YaoNie,YeYang,Genome-widesearchandcomparativegenomicanalysisofthetrypsininhibitor-likecysteine-richdomain-containingpeptides,Peptides,2014,53:106-114.(IF:2.6)(13)XuesongLuo,Xian-ChunZeng*,ZhancanHe,XiaoluLu,JieYuan,JingjingShi,MingLiu,YunfanPan,Yan-XinWang,Isolationandcharacterizationofaradiation-resistantbacteriumfromTaklamakanDesertshowingpotentabilitytoaccumulateLead(II)andconsiderablepotentialforbioremediationofradioactivewastes,Ecotoxicology,2014,23(10):1915-1921.(IF:2.7)(14)LianAo,Xian-ChunZeng*,YaoNie,YaoMu,LingliZhou,XuesongLuo,Flavobacteriumarsenatisspnov.,anovelarsenic-resistantbacteriumfromhigh-arsenicsediment,InternationalJournalofSystematicandEvolutionaryMicrobiology,2014,64:3369-3374.(IF:2.8)(15)YeYang,Xian-ChunZeng*,LeiZhang,YaoNie,WanxiaShi,YichenLiu,Androcin,aNovelTypeofCysteine-RichVenomPeptidefromAndroctonusbicolor,InducesAkinesiaandAnxiety-likeSymptomsinMice,IUBMBLife,2014,66(4):277-285.(IF:3.5)(16)LinghuaXu,Xian-ChunZeng*,YaoNie,XuesongLuo,EnminZhou,LingliZhou,YunfanPan,WenjunLi,Pontibacterdiazotrophicusspnov.,aNovelNitrogen-FixingBacteriumoftheFamilyCytophagaceae,PLosOne,2014,9(3):e92294.(IF:3.5)(17)ShifenWu,YaoNie,Xian-ChunZeng*,HanjunCao,LeiZhang,LingliZhou,YeYang,XuesongLuo,YichenLiu,GenomicandfunctionalcharacterizationofthreenewvenompeptidesfromthescorpionHeterometrusspinifer,Peptides,2014,53:30-41.(IF:2.6)(18)HanjunCao,YaoNie,Xian-ChunZeng*,LinghuaXu,ZancanHe,XuesongLuo,RinaWu,Pontibacteryuliensisspnov.,isolatedfromsoil,InternationalJournalofSystematicandEvolutionaryMicrobiology,2014,64:968-972.(IF:2.8)(19)Xian-ChunZeng*,LingliZhou,WanxiaShi,XuesongLuo,LeiZhang,YaoNie,JinweiWang,ShifenWu,BinCao,HanjunCao,ThreenewantimicrobialpeptidesfromthescorpionPandinusimperator,Peptides,2013,45:28-34.(IF:2.6)(20)Xian-ChunZeng*,XuesongLuo,San-XiaWang,XiZhan,Fibronectin-mediatedcellspreadingrequiresABBA-Rac1signaling,JournalofCellularBiochemistry,2013,114(4):773-781.(IF:3.4)(21)Xian-ChunZeng*,YaoNie,XuesongLuo,ShifenWu,WanxiaShi,LeiZhang,YichenLiu,HanjunCao,YeYang,JianpingZhou,Molecularandbioinformaticalcharacterizationofanovelsuperfamilyofcysteine-richpeptidesfromarthropods,Peptides,2013,41:45-58.(IF:2.6)(22)Xian-ChunZeng*,LeiZhang,YaoNie,XuesongLuo,IdentificationandmolecularcharacterizationofthreenewK+-channelspecifictoxinsfromtheChinesescorpionMesobuthusmartensiiKarschrevealingintronicnumberpolymorphismandalternativesplicinginduplicatedgenes,Peptides,2012,34(2):311-323.(IF:2.6)(23)Xian-ChunZeng*,SanxiaWang,YaoNie,LeiZhang,XuesongLuo,CharacterizationofBmKbpp,amultifunctionalpeptidefromtheChinesescorpionMesobuthusmartensiiKarsch:Gaininginsightintoanewmechanismforthefunctionaldiversificationofscorpionvenompeptides,Peptides,2012,33(1):44-51.(IF:2.6)(24)XuesongLuo,JunWang,Xian-ChunZeng*,YaqiongWang,LingliZhou,YaoNie,JunDai,ChengxiangFang,Mycetocolamanganoxydansspnov.,anactinobacteriumisolatedfromtheTaklamakandesert,InternationalJournalofSystematicandEvolutionaryMicrobiology,2012,62:2967-2970.(IF:2.8)(25)YaoNie,Xian-ChunZeng*,YeYang,FengLuo,XuesongLuo,ShifenWu,LeiZhang,JianpingZhou,AnovelclassofantimicrobialpeptidesfromthescorpionHeterometrusspinifer,Peptides,2012,38(2):389-394.(IF:2.6)(26)YaoNie,Xian-ChunZeng*,XuesongLuo,ShifenWu,LeiZhang,HanjunCao,JianpingZhou,LingliZhou,TremendousintronlengthdifferencesoftheBmKBTandanovelBmKBT-likepeptidegenesprovideamechanicalbasisfortherapidorconstitutiveexpressionofthepeptides,Peptides,2012,37(1):150-156.(IF:2.6)标签: 环境学院 中国地质大学(武汉)
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