个人简历

张亚妮，女，陕西渭南人，副教授，硕士生导师。2002年获得西北农林科技大学学士学位，2005年获得西北农林科技大学硕士学位，2010年6月获西北农林科技大学博士学位，其中2007年10至2009年10月在加拿大圭尔夫大学生物系进行博士生联合培养。2010年7月来扬州大学工作，主要承担本科生《动物遗传学》、《渔业资源评估》、《动物遗传学实验教程》和研究生《细胞遗传学》的教学工作。主持国家自然科学基金1项,江苏省自然科学基金1项，教育部博士点基金1项,中国博士后基金1项，中国博士后特别资助项目1项,江苏省重点研发计划（现代农业）重点项目1项，扬州大学创新培育基金2项;参加国家自然科学基金4项，国家转基因重大专项2项；发表论文30余篇；参与发明专利3件。
荣誉称号
1.鸡早期胚胎发育及生殖干细胞研究的理论与技术高等学校科学研究优秀成果奖自然科学奖教育部一等奖排名第三2016年
2.扬州大学教学成果奖二等奖排名第一2016年
3.基于思维与实践并行的动物遗传育种群研究性教学探索与实践扬州大学教学成果奖扬州大学二等奖排名第五2016年
4.扬州大学“青蓝工程”优秀骨干教师2016年
5.扬州大学“三下乡”社会实践先进工作者2011年
6.扬州大学校园“科技先锋”2015年
7.扬州大学最受欢迎的班主任2015年
8.扬州大学本科生优秀论文指导教师2016年
9.扬州大学微课比赛一等奖2017年
10扬州大学最受欢迎的任课教师2017年

近期论文

1.ZhangY,WangY,ZuoQ,LiD,ZhangW,WangF,JiY,JinJ,LuZ,WangM,ZhangC,LiB.CRISPR/Cas9mediatedchickenStra8geneknockoutandinhibitionofmalegermcelldifferentiation.Plosone.2017,12(2):e0172207.
2.YaniZhang,YingjieWang,QishengZuo,XiaoyanWang,DongLi,BeibeiTang1,2,BichunLi.SelectionoftheInducerfortheDifferentiationofChickenEmbryonicStemCellsintoMaleGermCellsInVitro.PLOSONE,201611(10),e0164664.
3.YaniZhang,QishengZuo,ZhiyongLiu,DongLi,BeibeiTang,Tian-rongXiao,ChaoLian,4.4.YingjieWang,KaiJin,YilinWang,WenhuiZhang,BichunLi.TheInductionEffectofAm80andTSAonESCDifferentiationviaRegulationofStra8inChicken.PLoSONE,2015,10(11):e0140262.doi:10.1371/journal.pone.0140262.
4.YaniZhang,YingjieWang,QishengZuo,DongLi,WenhuiZhang,ChaoLian,BeibeiTang,TianrongXiao,ManWang,KehuaWangandBichunLi.EffectsoftheTransformingGrowthFactorBetaSignalingPathwayontheDifferentiationofChickenEmbryonicStemCellsintoMaleGermCells.CELLULARREPROGRAMMING2016,18（6）:401.
5.YaniZhang,DezhiFu,HaoChen,ZhentaoZhang,QingqingShi,AhmedKamelElsayed,BichunLi.PartialAntiviralActivitiesDetectionofChickenMxJointingwithNeuraminidaseGene(NA)againstNewcastleDiseaseVirus.Plosone.2013,8(8):e71688.
6.YaniZhang,HaiyanYang,ZhentaoZhang,QingqingShi,DanWang,MengmengZheng,BichunLi,JiuzhouSong.Isolationofchickenembryonicstemcellandpreparationofchickenchimericmodel.MolBiolRep,2013,40(3):2149–2156.
7.YaniZhang,YapingJin,TeganA.Williams,SallyM.Burtenshaw,AmandaC.Martyn,RuiLu.AminoaciddeprivationinducesCREBZFexpressionviaanAAREinthepromoter.BiochemicalandBiophysicalResearchCommunication,2010,39(3),1352~1357.
8.YaniZhang,LiweiRen,WeiLi,QiXu,GuobinChang,XiaoyanWangandBichunLi.Cloningofneuraminidase(NA)geneandidentificationofitsantiviralactivity.AfricanJournalofBiotechnology.2012,11(47),10675-10681.
9.YaniZhang,YongxinHe,PengXue,YulinChen.SequencevariantintheKAP1.1geneassociatewithcashmeretraitintwocashmeregoatbreeds.AfricaJournalofAgricultureResearch.2011,6(12):2889-2894.
10.QishengZuo,DongLi,LeiZhang,AhmedKamelElsayed,ChaoLian,QingqingShi,ZhentaoZhang,RuiZhu,YinjieWang，KaiJin,JiuzhouSong,YaniZhang*,BichunLi.StudyontheregulatorymechanismofthelipidmetabolismpathwaysduringchickenmalegermcelldifferentiationbasedonRNA-seq.Plosone.,2015,DOI:10.1371/journal.pone.0109469（通讯作者）
11.AhmedKamelEl-Sayed,ZhentaoZhang,LeiZhang,ZhiyongLiu,LouiseC.Abbott,YaniZhang*,BichunLi,PluripotentStateInductioninMouseEmbryonicFibroblastUsingmRNAsofReprogrammingFactors.Int.J.Mol.Sci.2014,15(12),21840-21864.（通讯作者）
12.DongLi,QishengZuo,ChaoLian,LeiZhang,QingqingShi,ZhentaoZhang,YingjieWang,MahmoudF.Ahmed,BeibeiTang,TianrongXiao,YaniZhang,BichunLi.Regulatorymechanismofproteinmetabolicpathwayduringthedifferentiationprocessofchickenmalegermcell.nVitroCellular&DevelopmentalBiology-Animal51.7(2015):655-661.（通讯作者）
13.ChaoLian,QishengZuo,DongLi,LeiZhang,MahmoudF.Ahmed,TianrongXiao,BeibeiTang,YingjieWang,KaiJin,YaniZhang,BichunLi.BasingRNA-seqexploredtheregulatorymechanismofthecarbohydratemetabolismpathwaysduringchickenmalegermcelldifferentiation.InVitroCellular&DevelopmentalBiology-Animal,2015,51(7):690.（通讯作者）
14.ZhangLei,ZhuRui,ZuoQisheng,LiDong,LianChao,TangBeibei,XiaoTianrong,ZhangYani,LiBichun.ActivityAnalysisandPreliminaryInducerScreeningoftheChickenDAZLGenePromoter[J].Internationaljournalofmolecularsciences,2015,16(3):6595-6605.（通讯作者）
15.ZhangLei,ZuoQisheng,LiDong,LianChao,AhmedKamelElsayed,TangBeibei,SongJiuzhou,ZhangYani,LiBichun.StudyontheroleofJAK/STATsignalingpathwayduringchickenspermatogonialstemcellsgenerationbasedonRNA-Seq.Journalofintegrativeagriculture,2015,14(5):60354-7.（通讯作者）
16.ZhentaoZhang,AhmedKamelElsayed,QingqingShi,YaniZhang*,QishengZuo,DongLi,ChaoLian,BeibeiTang,TianrongXiao,QiXu,GuobinChang,GuohongChen,LeiZhang,KehuaWang,YingjieWang,KaiJin,YilinWang,JiuzhouSong,HengmiCui,andBichunLi.Crucialgenesandpathwaysinchickengermstemcellsdifferentiation.JournalofBiologicalChemistry,2015,290(21):13605.（通讯作者）
17.XiaoyanWang,YingjieWang,QishengZuo,DongLi,WenhuiZhang,ChaoLian,BeibeiTang,TianrongXiao,ManWang,KehuaWang,BichunLi,YaniZhang.Thesynergisticeffectof5-AzadcandTSAonmaintenanceofpluripotencyofchickenESCsbyoverexpressionofNANOGgene.InVitroCellular&DevelopmentalBiology-Animal,2016,52(4):488-496.（通讯作者）
18.YingjieWang,QishengZuo,YulinBi,WenhuiZhang,JingJin,LiangliangZhang,Ya-niZhang,BichunLi.miR-31RegulatesSpermatogonialStemCellsMeiosisviaTargetingStra8.[J].JournalofCellularBiochemistry,2017.（通讯作者）
19.WangY,BiY,ZuoQ,ZhangW,LiD,HeNN,ChengS,ZhangYN,LiB.MAPK8RegulatesChickenMaleGermCellDifferentiationThroughJNKSignalingPathway.JCellBiochem.2017Aug16.doi:10.1002/jcb.26314.（通讯作者）
20.DongLi,ShaozeCheng,WenhuiZhang,ManWang,ChanghuaSun,ChenZhang,YilinWang,JingJin,YaniZhang,BichunLiHedgehog-Gli1signalingregelatesdifferentiationofchicken(Gallusgallus)embryonicstemcellstomalegermcells.AnimalReproductionScience182(2017)9–20.（通讯作者）
21.DongLi,ManWang,ShaozeCheng,ChenZhang,YilinWang,WenhuiZhang,RuifengZhao,ChanghuaSun,YaniZhang,BichunLi.CYP1A1basedonmetabolismofxenobioticsbycytochromeP450regulateschickenmalegermcelldifferentiation.InVitroCell.Dev.Biol.—Animal.2017,53:293–303.（通讯作者）
22.ChenH,ZuoQ,WangY,SongJ,YangH,ZhangY,LiB.InducinggoatpluripotentstemcellswithfourtranscriptionfactormRNAsthatactivateendogenouspromoters.BMCBiotechnol.2017,17(1):11.doi:10.1186/s12896-017-0336-7.
23.QishengZuo,KaiJin,YaniZhang,JiuzhouSong,BichunLi.DynamicexpressionandregulatorymechanismofTGF-βsignalinginchickenembryonicstemcellsdifferentiatingintospermatogonialstemcells.BioscienceReportsJul07,2017,37(4),DOI:10.1042/BSR20170179.
24.ChenZhang,ManWang,NanaHe,MahmoudF.Ahmed,YilinWang,RuifengZhao,XinjianYu,JingJin,JiuzhouSong,QishengZuo,YaniZhang,BichunLi.Hsd3b2associatedinmodulatingsteroidhormonesynthesispathwayregulatesthedifferentiationofchickenembryonicstemcellsintospermatogonialstemcells.JCellBiochem.2017,DOI:10.1002/jcb.26279.
25.ZhentaoZhang,FengXu,YaniZhang,WeiLi,YanhuiYin,CaiyeZhu,LixinDu,A.K.Elsayed,BichunLi.CloningandexpressionofMyoGgenefromHusheepandidentificationofitsmyogenicspecificity.MolBiolRep(2014)41:1003–1013.
26.BCLi,WLi,HChen,YNZhang,ZTZhang,XYWang,BGao,TCDou,KHWang.TheInfluencingFactorofInVitroFertilizationandEmbryonicTransferintheDomesticFowl(Gallusdomesticus).ReprodDomAnim.2013,48(3):368-3728.
27.HaoChen,YanhuiYin,YaniZhang,MinSun,TingfengChen,CaiyeZhu,WeiLi,BichunLi,HuilinYang.ProductionoftransgenicmiceexpressingthegoatH-FABPgenebyintratesticularinjection.MolBiolRep.(2013)40:2215–2222.
28.YurongQin,HaoChen,YaniZhang,CaiyeZhu,BoGao,YanhuiYin,WeiLi,QingqingShi,MengmengZheng,QiXu,JiuzhouSong,BichunLi.CloningoftheXuhuaigoatPPARγgeneandthepreparationoftransgenicsheep.BiochemGenet.2013,51:543–553.
29.张亚妮，王颖洁，左其生，李东，张蕾，汤贝贝，连超，毕瑜林，张文慧，李碧春.5-Azadc和TSA对鸡Nanog基因启动活性及ESC多能性维持的影响[J].畜牧兽医学报,2015,46(12):2176-2184
30.张亚妮，任丽伟，李伟，徐琪，高波，王霄燕，李碧春.流感病毒NA基因的亚细胞定位及抗病毒活性研究.中国家禽.2012,34（20）:18-22.
31.张亚妮，杨海燕，施青青，张振韬，郑蒙蒙，王丹,李碧春.鸡胚胎干细胞的分离及其嵌合体制备条件探索.中国畜牧杂志.2012,48（21）:71-73.
32.张亚妮,陆锐.CREBZF启动子对4种氨基酸的应答效应.西北农林科技大学学报（自然科学版）.2011,39(10),192-198.
33.张亚妮，张恩平，吴迪，陈玉林.内蒙古绒山羊KAP基因与经济性状关系的研究.畜牧兽医学报，2007，38(5),447-451.
34.张亚妮，张恩平，吴迪，陈玉林.KAP基因的多态性与辽宁绒山羊经济性状的关系研究.中国农业科学,2007.40(9),2062-2067.