个人简历

学习经历
197.9-2001.7本科江西农业大学动物医学
2005.9-2010.7硕士/博士研究生扬州大学临床兽医学
进修情况
2017.9-2018.9韩国GyeongsangHationalUniversity访问学者
工作简历
2001.7-2005上海转基因研究中心
2010.6月至今扬州大学曾医学院讲师，副教授
2015年至2017年韩国KonkukUniversity博士后

研究领域

山羊、猫体细胞克隆与转基因克隆、动物转基因制药、人类动物疾病模型、功能纳米材料的制备及其在抗菌、抗肿瘤上的应用"科研情况
1.江苏省人兽共患病学重点实验室开放课题，基于乳铁蛋白修饰的纳米抗菌材料制备及其作用机制，R1807

近期论文

1.Yu-GuoYuan*,Yun-JungChoi,AbuMusaMdTalimurReza.NicotinamidearrestedmouseembryoatSphaseof2--cellwithconstitutiveacetylationofH3K56.2019，Submit
2.YuanYG*,XuL，Zhangs，MesalamA,LeeKL,LiuH,JooMD，IdreesM,KongIK*.
PolydatinandI-CBP112protectsearlybovineembryoagainstnicotinamide-induced
mitochondrialdysfunction.Theriogenology.2019Aug:134:1-10.2区，IF2.29
3.Yu-GuoYuan*，ShiminZhang,Ji-oonHwang，Il--KeunKong*.SilverNanoparticles
PotentiatesCytotoxicityandApoptoticPotentialofCamptothecininHumanCervical
CancerCells.0xidMedCellLongev,2018.2区，IF4.9
4.Yu-GuoYuan*，Yan-HongWang,SGurunathan*.Quercetinmediatedsynthesisographeneoxide-silvernanoparticlesnanocomposites:Asuitablealternativenanotherapyforneuroblastomacancer.IntJNanomedicine.2017，12:5819-5839.2区，IF4.32..
5.Yu-GuoYuan*，Qiu-LinPeng，SGurunathan*.Silvernanoparticlesenhancestheapoptoticpotentialofgemcitabineinhumanovariancancercells:Combinationtherapyforeffectivecancertreatment.IntJNanomedicine，2017，12:6487-6502.2区，IF4.32.
7.Yu-GuoYuan*，SGurunathan*.Combinationofgrapheneoxide--silvernanoparticles
nanocompositesandcisplatinenhancesapoptosisandautophagyinhumancervical
cancercells.IntJNanomedicine,2017,12:6537-6558.2区，IF4.32.
8.Yu-GuoYuan*，Qiu-LinPeng，sGurunathan*.EffectsofsilvernanoparticlesonmultipledrugresistantstrainsofStaphylococcusaureusandPseudomonasaeruginosafrommastitis--infectedgoats:Analternativeapproachforantimicrobialtherapy.INTJmMOL,2017,18(3):E569.2区，IF3.2.
10.Yu-GuoYuan,SongSao--Zheng,ZhuMeng-Ming,Zheng-YiHe，YongCheng*.Humanlactoferrinefficientlytargetedintocaprinebeta-lactoglobulinlocuswithTALENs.
Asian-AustralasJAnimSci.2017，30(8):1175-1182.2区，IF0.8
11.Yu-GuoYuan,YongCheng，Jin-YuWlang，Qiu-LinPeng*.Targetedmutagenesisof
beta-1actog1obulingeneincaprinefetalfibroblastsbycontext-dependentassembly
zincfingernucleases,0penAccessLibraryJournal,2016，3(1):e2813..
12.Yu-GuoYuan,LiYouAn,BaoLiYu,YongCheng*.ExpressionofRecombinantHuman
Alpha-LactalbuminintheMilkofTransgenicGoatsUsingaHybridPromoterEnhancer.
JournalofAnalyticalMethodsinChemistry,2014，(2):1~7.SCI，IF0.9
13.LiYouAn#，Yu-GuoYuan#，BaoLiYu,YongCheng*.Generationofhumanlactoferrin
transgenicclonedgoatsusingdonorcellswithdualmarkersandamodifiedselection
procedure.Theriogenology，2012，78:1303-1311.(#共同第一-作者).
14.YongCheng#*，LiYouAn#，Yu-GuoYuan#，etal.Hybridexpressioncassettesconsistingofamilkproteinpromoterandacytomegalovirusenhancersignificantlyincreasemanmary--specificexpressionofhumanlactoferrinintransgenicmice.MolReprodDev，2012，79:573-585.(#共同第--作者).IF2.8
16.Yu-GuoYuan,LiYouAn,BaoLiYu,YongCheng*.EffectofFol1icle-Stimulating
HormoneDosage,SeasonsandTreatmentFrequencyonSuper-0vulationinGoats.Animal
husbandyandfoodscience,2011,20(11):21-43..
17.袁玉国，安礼友，成勇*.以经过转染的乳腺上皮细胞生产克隆羊.生物工程学报，2009，
8:13-19.
18.LuR,YuanT,WangY，ZhangT,YuanY,WuuD,ZhouM,HeZ,Lu了,ChenY，FanJ,LiangJ,ChengY.Spontaneousseverehypercholesterolemiaandatherosclerosislesionsinrabbitswithdeficiencyoflow-densitylipoproteinreceptor(LDLR)onexon7.EBioMedicine.2018，36:29-38.2区，IF6.68
19.Songs,QiZ,ShaoB,ZhuM,MiF,ChengY*.EfficientTALEN-mediatedmyostatingeneeditingingoats.BMCDevBiol.2016,16(1):26.SCI,IF2.09
20.XingHShaoB，GuYY，Yu-GuoYuan,ZhangT，ZangJ，ChengY*.Analysisof
polymorphismsinmilkproteinsfromclonedandsexullyreproducedgoats.GenetMol
Res.2015,14(4):16196-203.sCI,IF0.76
21.Songs,Gex,ChengY,LuR,ZhangT,YuB,Jix,QiZ,RongY,Yu-GuoYuan,ChengY*.High-levelexpressionofanovelrecombinanthumanplasminogenactivator(rhPA)inthemilkoftransgenicrabbitsanditsthrombolyticbioactivityinvitro.MolBiol
Rep.2016，43(8):775-83.scI,IF1.69(*通讯作者)
SMBoneMarrowResearch杂志编委；ACSAppliedMaterials&Interfaces,Biologyof
Reproduction，Plos0ne，InternationalJournalofAnimalScience和农业生物技术学报特约中国畜牧兽医外科协会会员。