吴圣龙
近期热点
资料介绍
个人简历
学习、工作简历1986年7月毕业于江苏农学院畜牧专业,获学士学位,同年留校。2003年12月获扬州大学兽医专业硕士学位。2006年12月获扬州大学动物遗传育种与繁殖学博士学位。历任扬州大学动物科学与技术学院党委副书记、副院长、扬州大学科技处副处长、处长等职研究领域
(1)猪疾病抗性和免疫应答的调控机制(2)猪抗病育种和健康养殖"先后主持国家自然科学基金、国家转基因生物新品种培育科技重大专项、国家星火计划重点项目、江苏省科技支撑计划重点项目等科研项目20余项,其中国家级和部省级科研项目9项;获全国商业科技进步一等奖、全国农牧渔业丰收奖一等奖各1项。主要科研项目:1、“FUT1基因启动子区对断奶仔猪大肠杆菌抗性的调控机制分析”(国家自然科学基金,31472066)2、“鞘糖脂生物合成通路及关键基因对猪F18大肠杆菌抗性的调控机理研究”(国家自然科学基金,31172183)3、“太湖猪F18大肠杆菌抗性主效基因的筛选与功能研究”(国家自然科学基金,30972089)4、“抗仔猪腹泻病转基因猪新品系培育”(转基因生物新品种培育科技重大专项,2014ZX08006-001B)5、“抗仔猪腹泻病转基因猪育种新材料创制”(转基因生物新品种培育科技重大专项,2009ZX08006-004B)6、“家畜规模化高效健康养殖技术示范及推广”(国家星火计划重点项目,2012GA690003)7、“地方特色土种猪新品系及配套系选育”(江苏省科技支撑计划重点项目,BE2014357)8、“中梅山猪专门化母系选育及其与巴克夏猪杂交配套研究”(江苏省科技支撑计划,BE2013345)9、“苏太猪免疫应答评价体系建立及抗逆型配套系的培育”(江苏省科技支撑计划,BE2010371)"近期论文
近5年来带领课题组在ScientificReports、AnimalGenetics、PLosOne、Gene、Int.J.Mol.Sci、JournalofGenetics、中国农业科学、畜牧兽医学报、遗传、农业生物技术学报等国内外刊物上发表论文80余篇,其中SCI收录30篇,总影响因子超过60。1.ZhengchangWu,YingLiu,WenhuaDong,Guo-qiangZhu,ShenglongWu&WenbinBao.CD14intheTLRssignalingpathwayisassociatedwiththeresistancetoE.coliF18inChinesedomesticweanedpiglets.ScientificReports,2016,6:24611.2.SunL,WangJ,YinX,SunS,ZiC,ZhuG,WuS,BaoW.Identificationofa5-MethylcytosineSitethatmayRegulateC/EBPβBindingandDetermineTissue-SpecificExpressionoftheBPIGeneinPiglets.ScientificReports,2016,6:28506.3.Y.Liu,L.N.Gan,W.Y.Qin,S.Y.Sun,G.Q.Zhu,S.L.Wu,W.B.Bao.DifferentialexpressionofToll-likereceptor4signalingpathwaygenesinEscherichiacoliF18-resistantand-sensitiveMeishanpiglets.PolishJournalofVeterinarySciences,2016,19(2):303-308.4.DongWH,DaiCH,SunL,WangJ,SunSY,ZhuGQ,WuSL,BaoWB.Expressionofkeyglycosphingolipidbiosynthesis-globoseriespathwaygenesinEscherichiacoliF18-resistantandEscherichiacoliF18-sensitivepiglets.Animalgenetics,2016,47(4):428-435.5.R.W.Xia,W.Y.Qin,L.N.Gan,J.Wang,S.L.Wu,W.B.Bao.DifferentialexpressionofFUT1andFUT2inLargeWhite,Meishan,andSutaiporcinebreeds.GenetMolRes.2016,15(1):15017613.6.S.P.Zhu,X.M.Yin,L.Sun,S.Y.Sun,W.B.Bao,S.L.Wu.DifferentialexpressionofporcineTAP1geneindifferentpopulations.RussianJournalofGenetics.2015,51(3):308-312.7.WenhuaDong,XuemeiYin,LiSun,JingWang,ShouyongSun,GuoqiangZhu,ShenglongWu,WenbinBao.Age-associatedmethylationchangeofTAP1promoterinpiglet.Gene.2015,573:70-74.8.XueMeiYIN,YingLIU,WenHuaDONG,QiaoHuiZHAO,GuoQiangZHU,ShengLongWU,WenBinBAO.AssociationofMx1genepolymorphismwithsomeeconomictraitsinMeishanpigs.TurkishJournalofVeterinaryandAnimalSciences.2015,39:389-394.9.YingLIU,XueMeiYIN,RiWeiXIA,YongJiuHUO,GuoQiangZHU,ShengLongWU,WenBinBAO.AssociationbetweentheMUC4g.243A>GpolymorphismandimmuneandproductiontraitsinLargeWhitepigs.TurkishJournalofVeterinaryandAnimalSciences.2015,39:1-6.10.Z.C.Wu,Y.Liu,W.H.Dong,Y.J.Huo,S.L.Wu,W.B.Bao.IdentificationofBPIproteinproducedindifferentexpressionsystemanditsassociationwithEscherichiacoliF18susceptibility.GenetMolRes.2015,14(1):1111-1123.11.Z.C.Wu,Y.Liu,Q.H.Zhao,Y.J.Huo,S.L.Wu,W.B.Bao.Associationofsinglenucleotidepolymorphismsofexon4andexon10oftheBPIgenewithimmuneindexesinSutaipigs.GenetMolRes.2015,14(2):6048-6058.12.ZhengchangWu,RiweiXia,XuemeiYin,YongjiuHuo,GuoqiangZhu,ShenglongWuandWenbinBao.ProteomicanalysisofduodenaltissuefromEscherichiacoliF18-resistantand-susceptibleweanedpiglets.PLosOne.2015,10(6):e0127163.13.QiaohuiZhao,YingLiu,WenhuaDong,ShipingZhu,YongjiuHuo,ShenglongWu,WenbinBao.GeneticVariationsofTAP1GeneExon3AffectsGeneExpressionandEscherichiacoliF18ResistanceinPiglets.Int.J.Mol.Sci.2014,15:11161-11171.14.JingWang,XuemeiYin,LiSun,ShouyongSun,ChenZi,GuoqiangZhu,ShenglongWu,WenbinBao.CorrelationbetweenBPIGeneUpstreamCpGIslandMethylationandmRNAExpressioninPiglets.Int.J.Mol.Sci.2014,15:10989-10998.15.J.Wang,Y.Liu,W.H.Dong,Y.J.Huo,X.G.Huang,S.L.WuandW.B.Bao.DynamicchangesinTAP1expressionlevelsinnewborntoweaningpiglets,anditsassociationwithEscherichiacoliF18resistance.GenetMolRes.2014,13(2):3686-3692.16.ShipingZhu,YingLiu,WenhuaDong,XianruiZheng,GuoqiangZhu,ShenglongWu,WenbinBao.PolymorphismofFUT1GeneM307anditsRelationshipwithPartialImmuneIndexesandEconomicTraitsinYorkshirePigs.AsianJournalofAnimal&VeterinaryAdvances.2014,9(4):253-261.17.ChenZi,ZhengchangWu,JingWang,YongjiuHuo,GuoqiangZhu,ShenglongWuandWenbinBao.TranscriptionalActivityoftheFUT1GenePromoterRegioninPigs.Int.J.Mol.Sci.2013,14:24126-24134.18.WangJ,PanZY,ZhengXR,WuZC,SuXM,ZhuGQ,HuangXG,WuSL,BaoWB.TLR4geneexpressioninpigpopulationsanditsassociationwithresistancetoEscherichiacoliF18.GenetMolRes.2013,12(3):2625-2632.19.LuLiu,JingWang,QiaohuiZhao,ChenZi,ZhengchangWu,XianminSua,YongjiuHuo,GuoqiangZhu,ShenglongWu,WenbinBao.Geneticvariationinexon10oftheBPIgeneisassociatedwithEscherichiacoliF18susceptibilityinSutaipiglets.Gene.2013,523(1):70-75.20.J.Zhu,C.Zi,Z.C.Wu,L.Liu,X.R.Zheng,X.M.Su,G.Q.Zhu,X.G.Huang,S.L.WuandW.B.Bao.Age-dependentexpressionoftheBPIgeneinSutaipiglets.GenetMolRes.2013,12(2):2120-2126.21.L.Ye,C.Zi,Z.Y.Pan,J.Zhu,Z.D.Du,G.Q.Zhu,X.G.Huang,W.B.Bao,S.L.Wu.InvestigationoftherelationshipbetweenSLA-1andSLA-3geneexpressionandsusceptibilitytoEscherichiacoliF18inpost-weaningpigs.ComparativeImmunology,MicrobiologyandInfectiousDiseases.2012(35):23–30.22.LanYe,XianminSu,ZhengchangWu,XianruiZheng,JinWang,ChenZi,GuoqiangZhu,ShenglongWu,WenbinBao.AnalysisofDifferentialmiRNAExpressionintheDuodenumofEscherichiacoliF18-Sensitiveand-ResistantWeanedPiglets.PLoSONE.2012,7(8):e43741.23.Wen-binBao,LanYe,ChenZi,LuLiu,ChenZi,JingZhu,Zhang-yuanPan,Guo-qiangZhu,Xue-genHuang,Sheng-longWu.RelationshipbetweentheexpressionlevelofSLA-DQAandEscherichiacoliF18infectioninpiglets.Gene.2012(494):140–144.24.Wen-BinBao,LanYe,ChenZi,Xian-MinSu,Zhang-YuanPan,JinZhu,Guo-QiangZhu,Xiao-GuoHuang,Sheng-LongWu.Studyontheage-dependenttissueexpressionofFUT1geneinporcineanditsrelationshiptoE.coliF18receptor,Gene.2012(497):336–339.25.Wen-binBao,LanYe,Zhang-yuanPan,JingZhu,Zi-DongDu,Guo-qiangZhu,Xue-genHuang,Sheng-longWu.TheeffectofmutationatM307inFUT1geneonsusceptibilityofEscherichiacoliF18andgenenSutaipiglets.MolecularBiologyReports.2012,39(3):3131–3136.26.Wen-binBao,LanYe,JingZhu,Zhang-yuanPan,Guo-qiangZhu,Xue-genHuang,Sheng-longWu.EvaluationofM307ofFUT1geneasageneticmarkerfordiseaseresistancebreedingofSutaipigs.MolecularBiologyReports.2012,39(4):4223–4228.27.W.B.Bao,L.Ye,Z.Y.Pan,J.Zhu,Z.D.Du,G.Q.Zhu,X.G.HuangandS.L.Wu.MicroarrayanalysisofdifferentialgeneexpressioninsensitiveandresistantpigtoEscherichiacoliF18.AnimalGenetics.2012,43(5):525-534.28.W.B.BAO,L.YE,Z.Y.PAN,J.ZhU,G.Q.ZhU,X.G.HUANG,S.L.WU.AnalysisofpolymorphismintheporcineTLR4geneanditsexpressionrelatedtoEscherichiacoliF18infection.CzechJournalofAnimalScience.2011,56(11):475–482.29.W.B.Bao,L.Ye,J.Zhu,Z.Y.Pan,G.Q.Zhu,X.G.Huang&S.L.Wu.BeneficialgenotypeofswineFUT1genegoverningresistancetoE.coliF18isassociatedwithimportanteconomictraits.JournalofGenetics.2011,90(2):315–318.30.WEN-BinBao,LanYe,ZHANG-YuanPan,JinZhu,GUO-QiangZhu,XUE-GenHuangandSHENG-LongWu.PolymorphismofM307oftheFUT1geneanditsrelationshipwithsomeimmuneindexesinSutaipigs(Duroc×Meishan).BiochemicalGenetics.2011,49:665–673.江苏省规模猪场高效健康养殖公共技术服务中心主任江苏省生猪产业技术创新联盟副理事长江苏省太湖猪基因库及保种项目首席专家江苏省农业科技创新团队(东串猪选育)首席专家 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