胡娇
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资料介绍
个人简历
学习经历2003-2007本科西南民族大学动物医学2007-2010硕士研究生扬州大学预防兽医学2010-2014博士研究生扬州大学预防兽医学进修情况2015.6-至今中国扬州大学生物科学与技术学院博士后工作简历2014.9-2017.6扬州大学兽医学院讲师2017.7-至今扬州大学兽医学院副教授研究领域
1流感病毒致病机理研究及抗病毒新靶点发现2流感病毒蛋白功能及其与宿主互作机制研究3流感病毒新型疫苗和诊断试剂研发"主持项目:1《一种禽场高致病性离流感鉴别诊断和监测技术集成与示范研究》。2016.7-2020.12。国家重点研发计划。200万。项目编号:2016YFD05016012《高致病性H5N1禽流感病毒P相互作用宿主蛋白的鉴定及功能分析》。2016.1-2018.12。国家自然科学青年基金。24万。项目编号:315020763《流感病毒新发现PA-X蛋白致病机理研究》.2016.7-2018.7。中国博士后特别资助计划.15万。项目编号:2016T905154《流感病毒FA蛋白与宿主蛋白相互作用及其分子机制研究》.2015.7-2018.6。江苏省自然科学青年基金,20万。项目编号:BK201504445《H5N1禽流感病毒感染宿主细胞差异IncRNA的筛选及分析》。2015.7-2017.6。江苏省博士后科学基金。5万。项目编号:1501015B6《高致病性H5M1禽流感病毒FA蛋白与宿主互作研究》.2015.7-2017.6。江苏省高校自然科学面上项目.3万。项目编号:15KJB2300067。《H5N1亚型禽流感病毒(AIV)致病哺乳L动物的分子机制》。2011.7-2012.6江苏省普通高校研究生科研创新计划项目。8万。项目编号:CX11-0995参与项目:1《禽流感致病力差异的分子机制研究》.2016。7-2020.12。国家重点研发计划140万项目编号:2016YFD0500202-12《动物流感病毒变异、跨种间传播及致病的分子机制研究》.2010。3-2015.12。国家重点基础研究计划(978计划)。项目编号:2011CB5050083.《ILR7在同源疫苗抗体选择压下H9N2亚型禽流感病毒抗原变异中的作用》2012.1-2015.12。国家自然科学基金面上项目。项目编号:311723004。《影响H9N2禽流感病毒气溶胶传播效率的分子机制》.2012.1-2014.12。国家自然科学青年基金。项目编号:31101827"近期论文
1.JiaoHu(#)。ZengleiHu(#),XiaoquanWang,MinGu,ZhaoGao,YanyanLiang,ChunxiMa,XiaowenLiu,ShunlinHu,SujuanChen,DaxinPeng,XinanJiao,andXiufanLiu(*).Deepsequencingofthemouselungtranscriptomerevealsdistinctlongnon-codingRNAsexpressionasociatedwiththehighvirulenceofH5N1avianinfluenzavirusinmice.Virulence.2018;9(1):1092-111.doi:10.1080/21505594.2018.1475795.2.JiaoHu(#),ChunxiMa,XiufanLiu(*).PA-X:akeyregulatorofin?uenzaAviruspatho-genicityandhostimmwneresponses.MedMicrobiolInmnol.2018Jul10.10/30040-018-0548-.3.JiaoA,LiuxThePAinteractinghostproteinmucleolinactsasanantiviralfactorduringhighlypathogenicH5N1avianinfuenzavirusinfection.ArchViro1.2018Jul5.doi:10.107/500705-018-3926-8.4.Liu(*)iTRAQ-BasedQuantitativeProteomicsRevealsImportanthostfactorsInvolvedintheHighPathogenicityoftheH5N1avianinfuenzavirusinmice.MedicalMicrobiologyandInmunology.2017Ap:;206(2):125-147.doi:10.107/0040-016-0489-89Epub2016Dec20.5.ZhaoGao(#)。JiaoHu(#)。YanyanLiang,QianYang,KunYan,DongLiu,XiaoquanVang,MinGu,XiaowenLiu,ShunlinHu,ZengleiHu,HuimouLiu,WenboLiu,SujuanChen,DaxinPeng,Xin-anJiaoandXiufanLiu(*).GenerationandComprehensiveAnalysisofHostCe1lInteractomeofthePAProteinoftheHighlyPathogenicH5N1AvianInfluenzaVirusinManmalianCells.2017Apr28;8:739.doi:10.3389/fmicb.2017.007396.Hu,J(#).,Y.Mo,Z.Gao,X.Wang,IM.Gu,Y.Liang.L.Z.Chen,S.Hu,W.Liu,HLiu,s.Chen,XLiu,D.PengandX.Liu(*).PA8associatedearlyalleviationoftheacutel1unginjwycontributestotheattenuationofahighlypathogenicH5N1avianin?uenzavirusinmice.MedicalMicrobiologyandImunology.2016Aug;205(4):381-95.doi:10.1007/s00430-016-0461-2.Epub2016Jun11.7.Hu,J(#).,8.Liu(*).EndemicityofH9N2andH5N1AvianInfluenzaVirusesinPoultryinChinaPosesaSeriousThreattoPoultryindustryandPublicHealth.FrontiersofAgrioulturalScienceandEngineering.2016,3(1):11-24..8.Hu,J(#).Y.Mo,X.Wang,M.Gu,Z.Hu,L.Zhong,Q.Wu,X.Hao,S.Hu,V.Liu,H.Liu,x.LiuandX.Liu(*).PA-XDecreasesthePathogenicityofHighlyPathogenicH5N1InfluenzaAVirusinAvianSpeciesbyInhibitingVirusreplicationandHostResponse.Journalofvirology.2015Apr15;89(8):4126-42.9.Hu,J(#),Z.Hu,Q.Song,M.Gu,&.Liu,Z.Wang,S.Hhu,C.Chen,H.Liu,S.Chen,D.Peng,z.Liu(*).ThePAgene-mediatedlethaldisseminationandexcessiveinateimmuneresponsecontributetothehighvirulenceofavianinfluenzaH5N1virusinmice.Jounalofvirology.March2013;87:2660-2672.10.h,J(#).,Z.Hu,Y.Mo,Q.Wu,Z.Cui,Z.Duan,J.Huang,H.Chen,Y.Chen,m.Gu,x.Wang,S.Hu,H.Liu,x.LiuandX.Liu(*).ThePAandHAGene-MediatedHighViralLoadandIntenseImateInmuneResponseintheBrainContributetotheHighPathogenicityofH5M1AvianInf1uenzaVirusinMallardDucks.Journalofvirology.0ctober2013,87:11063-11075.11.Hu,J(#),R.Zhao,&.Liu,Z.Wang,Z.ChenandX.Liu(*).TwoHighlyPathogenicAvianInfluenzaH5N1VirusesofClade2.3.2.1withSimilarGeneticBackgroundbutwithDifferentPathogenicityinMiceandDucks.TransboundaryandEmergingDiseases.Apr2013;60(2):127-39.12.Hu,Z(#).,J.Hu,S.Hu,x.Liu,X.Wang,J.ZhuandX.Liu(*).2012.StronginnateimmuneresponseandcelldeathinchickensplenocytesinfectedwithgenotypeVIIdNewcastlediseasevirus.VirolJournal.9:208.13.CuiZ(#)。J.Hu,L.He,Q.Li,M.Gu,x.Wang,S.Hu,H.Liu,W.Liu,x.LiuandX.Liu(*).DifferentialimmuneresponseofmallardduckperipheralbloodmononuclearcellstotwohighlypathogenicavianinfluenzaH5N1viruseswithdistinctpathogenicityinmallardducks.ArchivesofVirology.2014Feb;159(2):339-43.14.HaoX(#)。HuJ,WangJ,XuJ,ChengH,XuY,LiQ,HeD,Liu&,WangX,GuM,HuS,XuX,LiuH,ChenS,PengD,LiuX(*).ReassortantH5N1avianinfluenzavirusescontainingPAorNPgenefromanH9N2virussignificantlyincreasethepathogenicityinmice.VeterinaryMicrobiology.2016Aug30;192:95--101.15.HuijieGao(#),YipengSun(#),JiaoHu,LuQi,JinliangWang;XinXiong,YuWang;QimingHe,YangLin,WeiliKong,Lai-GieaSeng,HongleiSun,JuanPu,Kin-ChowChang,XiufanLiu,JinhuaLiu(*).ThecontributionofPA-Xtothevirulenceofpandemic2009H1N1andhighlypathogenicH5N1avianinfluenzaviruses.Scientificreports.February2015,5;5:8262.16.HuijieGao(#),HongleiSun(#),JiaoHu,LuQi,JinliangWang,XinXiong,YuWang,QimingHe,YangLin,WeiliKong,Lai-GieaSeng,HongleiSun,JuanPu,Kin-ChowChang,XiufanLiu,JinhuaLiu,YipengSun(*).The20aminoacidsattheC-terminusofPA-XareassociatedwithincreasedinfluenzaAvirusreplicationandpathogenicity.JournalofGeneralVirology.2015Aug;96(8):2036-49.17.HongleiSun(#),JuanPu(#),JiaoHu,LitaoLiu,GuanlongXu,GeorgeFuGao,XiufanLiu,JinhuaLiu(*).Characterizationofclade2.3.4.4highlypathogenicH5avianinfluenzavirusesinducksandchickens.VetMicrobiol.2016;182:116-22.18.Hu,J(#).,Z.Hu,Y.MoandX.Liu(*).Progressinidentifyingvirulencedeterminantsoftheavianinfluenzavirusesinmanmals.ChinesePoultry.2013,35(10):38-4219.Hu,J(#).,Zeng1eiHu,XiaowenLiu,XiaoquanWang,MinGu,ShunlinHu,JunqingHuang,HongzhiChen,YuxinChen,YiqunMo,QiwenWru,WenboLiu,SujuanChen,DaxinPeng,XiufanLiu(*).ThePAandHAgenecontributetothehighvirulenceofH5N1avianinfluenzavirusinmallardducks.XVIIIthWorldVeterinaryPoutryAssociation.19th-23rdAugust2013.Nantes.France.Conferencepaper.20.Hu,J(#).,Y.Mo,X.Wang,M.Gu,Z.Hu,L.Zhong,Q.Wu,X.Hao,S.Hu,W.Liu,H.Liu,X.LiuandX.Liu(*).PA:-XDecreasesthePathogenicityofHighlyPathogenicH5N1InfluenzaAVirusinAvianSpeciesbyInhibitingVirusreplicationandHostResponse.19thWorldVeterinaryPoutryAssociation.7-11September2015.Capetown.SouthAfrica.Conferencepaper.21.胡娇(#),高照,刘秀梵(*).A型流感病毒与宿主相互作用研究进展。中国家禽,2016,第38卷第24期。标签: 扬州大学 兽医学院(比较医学研究院)
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