个人简历

学习经历
2004-2009本科南京农业大学动物药学
2009-2015博士研究生南京农业大学基础兽医学
进修情况
2012-2014美国LouisianaStateUniversityHealthSciencesCent联合培养
工作简历
2018.4-至今扬州大学兽医学院讲师
20152018南京师范大学生命科学学院博士后、讲师

研究领域

兽医药理与毒理
肿瘤药理与细胞信号转导"科研情况
基于AK通路的马度米星调控内质网应激致骨骼肌毒性分子机理硏究，国家自然科学基金青年科学基金项目

近期论文

1.xinChen,YumeiZhang,ShanxiangJiang*,ShileHuang*,MaduramicininducesapoptosisthroughROS-PP5-JNKpathwayinskeletalmyoblastcellsandmuscletissue.Toxicology.
2019,424:152239.
2.XinChen,YueLi,MengFeng,XiaoyuHu,HaiZhang,RuijieZhang,XiaoqingDong,ChunxiaoLiu,ZhaoZhang,ShanxiangJiang,ShileHuang*,LongChen*.MaduramicininducescardiacmusclecelldeathbytheROS-dependentPTEN/Akt-Erk1/2signalingpathway.Journalofcellularphysiology.2019,234(7):10904-10976
3.XinChen,QianhanWei,QianqianLu,ZetingZhao,ZhengrongYu,YumeiZhang*.SodiumdehydroacetateinducescoagulationdysfunctionbyinhibitinglivervitaminKepoxidereductasecomplexsubunit1inwistarrats.Researchinveterinaryscience.2019,124:39-405
4.XinChenff,XiaoyuHuff,YueLi,CuilanZhu,xiaoqingDong,RuijieZhang,Jingma.ShileHuang*,LongChen*.ResveratrolinhibitsErk1/2-mediatedadhesionofcancercellsviaactivatingPP2A-PTENsignalingnetwork.Journalofcellularphysiology.2019,234(3):28222836
5.xinChen,ShanxiangJiang,ShileHuang*,Maduxamicin-activatedproteinphosphatase2Aresultsinextracellularsignal-regulatedkinase1/2inhibition,leadingtocytotoxicityinmyocardialH9c2cells.Toxicologyletters.2018,284:96-102.
6.XinChen,LongChen,ShanziangJiang*,ShileHuang*.Maduramicininducesapoptosisandnecrosis,andblocksautophagicfluxinmyocardialH9c2cells.Journalofappliedtoxicology.2018,38(3):366-375
7.XinChen,YingGu,KarnikaSingh,ChaoweiShang,MansourehBarzegar,ShanxiangJiang*,ShileHuang*.Maduramicininhibitsproliferationandinducesapoptosisinmyoblastcells.Plosone.2014,9(12):e115652