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崔恒宓
2023-05-16 09:34
  • 崔恒宓
  • 崔恒宓 - 教授 博导-扬州大学-动物科学与技术学院-个人资料

近期热点

资料介绍

个人简历


于1997年获瑞典Uppsala大学博士学位,其后在美国约翰霍普金斯大学先后作博士后、讲师和副教授,美国国家卫生研究院(NIH)资深科学家。曾获得约翰霍普金斯大学W.BarryWood优秀博士后奖和优秀Jr.Faculty基础研究奖。担任《BMCMedicalGenetics》等多个SCI杂志副主编或编委。曾担任美国NIH研究项目评委、意大利和奥地利国家科学基金特邀评委。在SCI杂志发表论文70多篇,包括《Nature》、《Science》等世界一流杂志。文献引用超过8600次。
2013年被扬州大学作为重点引进人才,聘为特聘教授、扬州大学表观遗传学及表观基因组学研究所所长。同年,入选“江苏省高层次创新创业人才引进人才”,担任江苏省双创人才联合会常务理事兼生物医学专委会副主任。回国后,积极开展国际前沿研究,特别是在内源性反转录病毒这个未开垦领域,目前已取得具有重大科学意义的突破性进展,还发现了癌基因致癌新表观遗传机制和肿瘤药物去甲基化试剂AZA抗肿瘤的新机制。先后主持“973”课题1项、国家自然科学基金重大研究计划项目1项、国家自然科学基金面上项目3项和参加国家重点研发计划项目1项。发表SCI论文20余篇(其中一区2篇,二区2篇),申请国家发明专利17项。创立了扬州大学表观遗传学及表观基因组学研究所,主办国际肿瘤表观遗传学会议,为国内表观遗传学研究做出了积极贡献。开设研究生《表观遗传学》和《分子生物学》课程。四年里,已培养和正在培养博士后、硕博士生25名。
1学习经历:
1997/08-2000/06美国约翰霍普金斯(JohnsHopkins)大学医学院博士后,导师:Professor.Andrew  Feinberg
1993/09-1997/05瑞典乌普撒拉(Uppsala)大学
发育和分子遗传系博士,导师:Professor:Rolf  Ohlsson
1982/02-1985/01扬州大学(原江苏农学院)  畜牧兽医系硕士,导师:张照教授
1978/03-1982/01南京农业大学(原南京农学院)畜牧兽医系学士
2工作经历:
2013/01-至今扬州大学表观遗传学及表观基因组研究所所长特聘教授
2011/11-2013/01美国国家卫生研究院癌症研究所(NCI/NIH)资深科学家
2003/07-2010/06美国约翰霍普金斯大学医学院副教授
2000/06-2003/06美国约翰霍普金斯大学医学院讲师(Instructor)
1992/11-1993/10英国剑桥大学Babraham研究所访问学者
1992/01-1992/10扬州大学动物科学与技术学院副教授
1989/04-1992/01扬州大学动物科学与技术学院讲师
1986/02-1989/03扬州大学动物科学与技术学院助教
1985/02-1986/01中国科学院上海细胞生物学研究所进修

研究领域


1)表观遗传学与动物育种;
2)干细胞表观遗传学及其应用;
3)肿瘤表观遗传学机制;
4)内源性反转录病毒的作用和功能"科研情况:
1.环境因素及表观遗传学在肾小球损伤中的机制(2012CB517605)国家973项目课题,2012-2016,课题主持人
2.结直肠癌IGF2基因内含子miR-483的致癌机制研究(81171965),国家自然科学基金面上项目,2012-2015,主持人
3.反义RNA及抑癌基因表观遗传学沉默分子机制研究(81372237),国家自然科学基金面上项目,2014-2017,主持人
4.源于鸡内源性白血病病毒的反义长非编码RNA的功能及表观遗传学调控机制(91540117)自然科学基金重大研究计划,2016-2018

近期论文


英文文章
1.JinR,andCuiH,ReproductivecharacteristicsofTaihupigs,PigNews&Information(Britain),3:99-102,1992.
2.EkstromTJ,CuiH,LiX,andOhlssonR.Promoter-specificIGF2imprintingstatusanditsplasticityduringhumanliverdevelopment,Development,1995;121:309-316.IP:85
3.EkstromTJ,CuiH,NystromA,RutanenEM,andOhlssonR.MonoallelicexpressionofIGF2atthehumanfetal/maternalboundary,MolReprodandDevelop,1995;41:177-183.
4.LiX,AdamG,CuiH,SandstedtB,OhlssonR,andEkstromTJ.Expression,promoterusageandparentalimprintingstatusofIgf2inhumanhepatoblastoma:uncouplingofIGF2H19imprinting.Oncogene,1995;11:221-229.
5.OhlssonR,EkstromT,FranklinG,Pfeifer-OhlssonS,CuiH,MillerS,FisherR,andWalshC.PlasticityofImprinting.InGenomicimprinting:CausesandConsequences.(R.Ohlsson,K.HallandM.Ritzen,Eds.),CambridgeUniversityPress.1995;pp.182-194.
6.CuiH#,XuWX,PowellD,andNewmanB.Cloningandsequencingofapigcdc25tyrosinephosphatasecDNA,JournalofAnimalScience,1995;73:630.
7.CuiH#andOhlssonR.,Animprovedprotocolforpurificationof35S-labelledoligonucleotideDNAprobesforinsituhybridizationapplications.TrendsinGenetics,1996;12:506-507.
8.LiX,CuiH,SandstedtB,NordlinderH,LarssonE,andEkstromTJ.ExpressionlevelsoftheIgf2inthehumanliver:developmentalrelationshipsofthefourpromoters,JournalofEndocrinology,1996;149:117-124.
9.AdamGI,CuiH,MillerSJ,FlamF,andOhlssonR,Allelicspecificinsituhybridizationanalysis:anoveltechniquewhichresolvedifferentialallelicusageofH19withinthesamecelllineageduringhumanplacentaldevelopment.Development,1996;122:839-847.
10.CuiH#,HedborgF,HeL,NordenskjoldA,SandstedtB,Pfeifer-OhlssonS,andOhlssonR.InactivationofH19,animprintedandputativerepressorgene,isapreneoplasticeventduringWilms'tumorigenesis,CancerResearch,1997;57:4469-473.
11.CuiH#,HoronIL,OhlssonR,HamiltonSR,andFeinbergAP.Lossofimprintinginnormaltissueofcolorectalcancerpatientswithmicrosatelliteinstability.NatureMedicine,1998;4:1276-1280.
12.LiYM,FranklinG,CuiH,SvenssonK,HeXB,AdamG,OhlssonR,andPfeiferS.TheH19transcriptisassociatedwithpolysomesandmayregulateIGF2expressionintrans.JournalofBiologicalChemistry,1998;273:28247-28252.
13.RandhawaGS#,CuiH#,BarlettaJA,Strichman-AlmashanuLZ,TalpazM,KantarjianH,DeisserothAB,ChamplinRC,andFeinbergAP.Lossofimprintingindiseaseprogressioninchronicmyelogenousleukemia.Blood,1998;91:3144-3147.(*Co-firstauthor)
14.HeL,CuiH,WalshC,MattssonR,LinW,AnnerenG,Pfeifer-OhlssonS,andOhlssonRHypervariableallelicexpressionpatternsoftheimprintedIGF2geneintumorcells.Oncogene,1998;16:113-119.
15.OhlssonR,CuiH,HeL,PfeiferS,MalmikumpuH,JiangS,FeinbergAP,andHedborgF.MosaicallelicIGF2expressionpatternsrevealalinkbetweenWilms’tumorigenesisandepigeneticheterogeneity.CancerResearch,1999;59:3889-3892.
16.OhlssonR,FlamF,FisherR,MillerS,CuiH,PfeiferS&AdamGI.RandommonoallelicexpressionoftheimprintedIGF2andH19genesintheabsenceofdiscriminativeparentalmarks.DevelopmentinGenesEvolution,1999;209:113-119.
17.Uejima,H,Lee,MP,Cui,H,andFeinberg,AP.HotstopPCR:Asimpleandgeneralassayforlinearquantitationofalleleratios.NatureGenetics,2000;25:375-376.
18.Ohlsson,R.,Svensson,K.,Cui,H.,Malmikumpu,H.andAdam,G.Allele-specificinsituhybridisation(ASISH)MethodsinMolecularBiology:Genomicimprinting(A.Ward,editor;HumanaPressInc.,Totowa,NewJersey,USA).2001;pp153-169.
19.CuiH#,NiemitzEL,RavenelJD,OnyangoP,BrandenburgSA,LobanenkovVV,andFeinbergAP.LOIofIGF2inWilms’tumorcommonlyinvolvesalteredmethylationbutnotmutationsofCTCForitsbindingsite.CancerResearch,2001;61:4947-4950.
20.RheeI,BachmanKE,ParkBH,JairK-W,R-WC,Yen,SchuebelKE,CuiH,FeinbergAP,LengauerC,KinzlerKW,BaylinSB,andVogelsteinB.DNMT1andDNMT3Bcooperatetosilencegenesinhumancancercells,Nature,2002,;416:552-556.
21.LoukinovDI,PugachevaE,VatolinS,PackSD,MoonH,ChernukhinI,MannanP,LarssonE,KanduriC,VostrovAA,CuiH,NiemitzEL,RaskoJE,DocquierFM,KistlerM,BreenJJ,ZhuangZ,QuitschkeWW,RenkawitzR,KlenovaEM,FeinbergAP,OhlssonR,MorseHC3rd,LobanenkovVV.,BORIS,anovelmalegerm-line-specificproteinassociatedwithepigeneticreprogrammingevents,sharesthesame11-zinc-fingerdomainwithCTCF,theinsulatorproteininvolvedinreadingimprintingmarksinthesoma.ProcNatlAcadSciUSA,2002;99:6806-6811.
22.Onyango,P,Jiang,S,Uejima,H,Shamblott,MJ,Gearhart,JD,Cui,H,andFeinberg,AP.Imprintinginhumanembryonicgermcellswithoutgermlinetransmission,ProcNatlAcadSciUSA,2002;99:10599-604.
23.Feinberg,A.P.,Cui,H.andOhlsson,R.DNAmethylationandgenomicimprinting:Insightsfromcancerintoepigeneticmechanisms.SeminarsinCancerBiology,2002;12:389.
24.CuiH#,OnyangoP.,BrandenburgS,WuY.,HsiehC-LandFeinbergAP.LossofimprintinginhumancolorectalcancerslinkedtohypomethylationofH19andIGF2,CancerResearch,2002;62:6442-6446.
25.Cruz-CorreaM,CuiH,PoweN,GiardielloFM,FeinbergA.,LossofimprintingoftheIGF2geneisadiffusecolorectalmolecularabnormalitywhichmaypredictcolorectalcancerrisk,Gastroenterology,2002;122:297Suppl.
26.Cruz-CarreaM,CuiH,GiardielloFM,PalmerA,HylindL,FeinbergA,LossofimprintingofIGF2isanepigeneticmarkerindependentlyassociatedwithcolorectalcancerandnotrelatedtotobaccooralcoholconsumption,Gastroenterology,2003;124:A550-A550Suppl.
27.CuiH#.,Cruz-CorreaM.,GiardielloF.M.,HutcheonD.F.,KafonekD.R.,BrandenburgS.,WuY.,HeX.,PoweN.R,.&FeinbergA.P.,LossofIGF2Imprinting:APotentalMarkerofColorectalCancerRisk.Science,2003;299:1753-1755.
28.Cruz-CorreaM.,CuiH.,GiardielloF.M.,PoweN.R,HylindL.,RobinsonA.,HutcheonD.F.,KafonekD.R.,BrandenburgS.,WuY.,HeX.,.&FeinbergA.P.LossofimprintingofIGF2gene,apotentialheritablebiomarkerforcolonneoplasiapredisposition.Gastroenterology,2004;126:964-70.
29.Cruz-CorreaM,ZhaoRH,HylindL,CuffariC,CuiH,FeinbergA,GiardielloF.Genomicimprintingoftheinsulingrowthfactor-2geneisaconstantepigeneticabnormalityassociatedwithcolorectalcancerrisk.Gastroenterology,2004;126:A2-A3Suppl.
30.HuY,ZhengM,XuZ,WangX&CuiH*.QuantitativerealtimePCRtechniqueforrapidprenataldiagnosisofdownsyndrome.PrenatalDiagnosis,2004;24:704-707.
31.CuiH#,GiusH#,BradburyCM,CookJ,SmartDK,ZhaoS,YoungL,BrandenburgSA,HuY,MunsonPJ,ChuangEY,MitchellJB,andFeinbergAP,DistinctEffectsonGeneExpressionofChemicalandGeneticManipulationoftheCancerEpigenomeRevealedbyaMultimodalityApproach.CancerCell,2004;6:361-371.
32.BjornssonHT,CuiH,GiusD,FallinMD,FeinbergAP.,Thenewfieldofepigenomics:implicationsforcancerandothercommondiseaseresearch,ColdSpringHarbSympQuantBiol.,2004;69:447-56.
33.YangR,MurilloFM,CuiH,BlosserR,UematsuS,TakedaK,AkiraS,ViscidiRP,RodenRB.,Papillomavirus-likeparticlesstimulatemurinebonemarrow-deriveddendriticcellstoproducealphainterferonandTh1immuneresponsesviaMyD88,JVirol.,200478:11152-60.IP:66
34.HuYL,ChenX,ChenLL,XuZF,WangXR,CuiH*.(2006)Comparativegenomichybridizationanalysisofspontaneousabortion,InternationalJournalofGynecology&Obstetrics,2006;92:52-57.
35.CuiH#*,LossofimprintingofIGF2asanepigeneticmarkerfortheriskofhumancancer(review),DiseaseMarkers,2007;23:105-112.
36.ReinholdWC,ReimersMA,MaunakeaAK,KimS,LababidiS,ScherfU,ShankavaramUT,ZieglerMS,StewartC,Kouros-MehrH,CuiH,DolginowD,ScudieroDA,PommierYG,MunroeDJ,FeinbergAP,WeinsteinJN,DetailedDNAmethylationprofilesoftheE-cadherinpromoterintheNCI-60cancercells,MolCancerTher.,2007;6:391-403.
37.DaiY,WangZ,LiJ,GuX,ZhengM,ZhouJ,YeX,YaoJ,HuYandCuiH*,ImprintingstatusofIGF2incordbloodcellsofHanChinesenewborns,Int.J.Mol.Sci.,2007;8:273-283.
38.YuW,GiusG,OnyangoP,KarpJ,FeinbergAPandCuiH*,Epigeneticsilencingoftumorsuppressorgenep15byitsantisenseRNA,Nature,2008;451:202-206.
39.SunL,HuangL,NguyenP,BishtKS,Bar-SelaG,HoAS,BradburyCM,YuW,CuiH,LeeS,TrepelJB,FeinbergAP&GiusD.DNAmethyltransferase1and3BactivateBAG-1expressionviarecruitmentofCTCFL/BORISandmodulationofpromoterhistonemethylation,CancerResearch,2008;68:2726-2735.
40.CuiH#,NguyenP,BishtK,SunL,PatelK,LeeR,KogohH,OshimuraM,OshimuraM,FeinbergAP,GiusD.CTCFL/BORISisamethylationindependentDNA-bindingproteinthatpreferentiallybindstothepaternalH19DMR,CancerResearch,2008;68:5546-51.
41.BjornssonHT,SigurdssonMI,FallinMD,IrizarryRA,AspelundT,CuiH,YuW,RongioneMA,EkströmTJ,HarrisTB,LaunerLJ,EiriksdottirG,LeppertMF,SapienzaC,GudnasonV,FeinbergAP.Intra-individualChangeOverTimeinDNAMethylationWithFamilialClustering,JAMA.2008;299:2877-2883.
42.NguyenP,Bar-SelaG,SunL,BishtKS,CuiH,KohnE,FeinbergAP,GiusD.BAT3andSET1AformacomplexwithCTCFL/BORIStomodulateH3K4histonedimethylationandgeneexpression,MolCellBiol.,2008;28:6720-6729.
43.IrizarryRA,Ladd-AcostaC,WenB,WuZ,MontanoC,OnyangoP,CuiH,GaboK,RongioneM,WebsterM,JiH,PotashJB,SabunciyanS,FeinbergAP.Thehumancoloncancermethylomeshowssimilarhypo-andhypermethylationatconservedtissue-specificCpGislandshores.NatureGenetics,2009;41:178-186.
44.Cruz-CorreaM,ZhaoR,OviedoM,BernabeRD,LacourtM,CardonaA,Lopez-EnriquezR,WexnerS,CuffariC,HylindL,PlatzE,CuiH,FeinbergAP,GiardielloFM.Temporalstabilityandage-relatedprevalenceoflossofimprintingoftheinsulin-likegrowthfactor-2gene.Epigenetics,2009;27;4(2).
45.ZhaoR,DeCoteauJF,GeyerCR,GaoM,CuiH,CassonAG.Lossofimprintingoftheinsulin-likegrowthfactorII(IGF2)geneinesophagealnormalandadenocarcinomatissues.Carcinogenesis,2009;30(12):2117-22.
46.CuiI&CuiH*,AntisenseRNAandepigeneticregulation,Epigenomics,2010;2(1):139-150.
47.ZhangY,DiaoZ,SuL,SunH,LiR,HuY,CuiH*,miRNA-155contributestopreeclampsiabydownregulatingCYR61,AmJObstetGynecol.,2010;202(5):466.e1-7.
48.RodriguezBA,WengYI,LiuTM,ZuoT,HsuPY,LinCH,ChengAL,CuiH,YanPS,HuangTH,Estrogen-MediatedEpigeneticRepressionoftheImprintedGeneCyclinDependentKinaseInhibitor1CinBreastCancerCells.Carcinogenesis.2011,32(6):812-21.
49.CuiH#*,AntisesneRNAsandmodulationoftumorsuppressorgenes,LongNon-codingRNAs:RegulationofGeneExpressionandDriversofNaturalSelection,HorizonScientificPress,2011,153-166.
回国后
50.ZhaoX,TangZ,ZhangH,AtianjohFE,ZhaoJY,LiangL,WangW,GuanX,KaoSC,TiwariV,GaoYJ,HoffmanPN,CuiH,LiM,DongX,TaoYX,AlongnoncodingRNAcontributestoneuropathicpainbysilencingKcna2inprimaryafferentneurons.NatureNeuroscience,2013,16(8):1024-31.
51.JeongY,DuR,ZhuX,YinS,WangJ,CuiH,CaoW,andCharlesJ.Lowenstein.HistoneDeacetylaseisoformsregulateinnateimmuneresponsebydeacetylatingmitogen-activatedproteinkinasephosphatase.JLeukocyteBiol.,2014,95(4):651-9
52.ZhangZ,ElSayedAK,ShiQ,ZhangY,ZuoQ,LiD,LianC,TangB,XiaoT,XuQ,ChangG,ChenG,ZhangL,WangK,WangY,JinK,WangY,SongJ,CuiH,LiB,CrucialGenesandPathwaysinChickenGermStemCellsDifferentiation.JBiolChem.,2015,290(21):13605-21.
53.YusufMS,HassanMA,ElnabtitiAS,CuiH*,Asingledoseofgingerpowder,supportedwithorganicacidorprobiotic,maximizesthelaying,eggqualityhatchabilityandimmuneperformancesoflayingjapanesequails,InternationalJournalofRecentScientificResearch,2015,6(10),6707-6711.
54.GengT,XiaL,LiF,XiaJ,ZhangY,WangQ,YangB,MontgomeryS,CuiH,DaoqingGong,Theroleofendoplasmicreticulumstressandinsulinresistanceintheoccurrenceofgoosefattyliver,BiochemBiophysResCommun.,2015,465,83-87.
55.GaoB,ShenD,XueS,ChenC,CuiH*andSongC*,Thecontributionoftransposableelementstosizevariationsbetweenfourteleostgenomes,MobileDNA,2016,Feb9;7:4.1-16doi:10.1186/s13100-016-0059-7.
56.HuX,ZhuW,ChenS,LiuY,SunZ,GengT,WangX,GaoB,SongC,QinAandCuiH*,ExpressionoftheenvgenefromtheavianendogenousretrovirusALVEandregulationbymiR-155,ArchivesofVirology,2016,;161(6):1623-32.
57.ZhaoJ,YaoJ,LiF,YangZ,SunZ,QuL,WangK,SuY,GengT,CuiH*,Identificationofcandidategenesforchickenearly-andlate-feathering,PoultryScience,2016,95(7):1498-503.
58.HuX,ZhuW,ChenS,LiuY,SunZ,GengT,WangX,GaoB,SongC,QinAandCuiH*,Expressionpatternsofendogenousavianretroviruses,ALVE1,anditsresponsetoinfectionofexogenousaviantumorviruses,ArchivesofVirology,2017,162(1):89-101.
59.CuiH#*,LiuY,JiangJ,LiuY,YangZ,WuS,CaoW,IH.Cui,YuC,IGF2-derivedmiR-483mediatedoncofunctionthroughtargetingDLC1andwasapotentialnoninvasivebiomarkerofcolorectalcancer,Oncotarget,2016,7(30):48456-48466.
60.GengT,ZhaoX,XiaL,LiuL,LiF,YangB,WangQ,MontgomeryS,CuiH,GongD.Supplementingdietarysugarpromotesendoplasmicreticulumstress-independentinsulinresistanceandfattyliveringoose.BiochemBiophysResCommun.,2016May28.pii:S0006-291X(16)30899-3.doi:10.1016/j.bbrc.2016.05.149.
61.ChenS,HuX,ZhuW,JiaC,HanX,SunZ,YangZ,GengT,CuiH*,Reactivationofdevelopment-relatedgenesbytheDNAmethylationinhibitor5-Aza-2΄-deoxycytidineinchickenembryofibroblasts,PoultryScience,201796(4)1007-1014,doi:10.3382/ps/pew378.
62.YusufMS,HassanMA,Abdel-DaimMM,ElnabtitiAS,AhmedAM,MoawedSA,El-SayedAK,CuiH*ValueaddedbySpirulinaplatensisintwodifferentdietsongrowthperformance,gutmicrobiota,andmeatqualityofJapanesequails,VeterinaryWorld,20169(11):1287-1293.
63.MohamedS.Yusuf,MohammedT.Ibrahim,HayamM.Sam,ManalM.A.MahmoudandHengmiCui*,Yeast,Lactose,andOrganicAcidsMixtureImprovedZoologicalGrowthandImmuneStatusofJapanesequails,NatureandScience,201614(4):1-13.
64.LiuY,HanX,YuanJ,GengT,ChenS,HuX,CuiIH,CuiH*.BiallelicinsertionofatranscriptionalterminatorviatheCRISPR/Cas9systemefficientlysilencesexpressionofprotein-codingandnon-codingRNAgenes.JBiolChem.,2017292(14):5624-5633.
65.GaoB,WangS,WangY,ShenD,XueS,ChenC,CuiH,SongC.Lowdiversity,activity,anddensityoftransposableelementsinfiveaviangenomes.FunctIntegrGenomics,2017Jul;17(4):427-439.doi:10.1007/s10142-017-0545-0.
66.GaoD,HermanJG,CuiH,JenJ,FuksF,BrockMV,UshijimaT,CroceC,AkiyamaY,GuoM.MeetingReportoftheFifthInternationalCancerEpigeneticsConferenceinBeijing,China,Epigenomics,2017Jul;9(7):937-941.doi:10.2217/epi-2017-0030.
67.LiH,LvB,KongL,XiaJ,ZhuM,HuL,ZhenD,WuY,JiaX,ZhuS,CuiH*.Nova1mediatesresistanceofratpheochromocytomacellstohypoxia-inducedapoptosisviatheBax/Bcl-2/caspase-3pathway.IntJMolMed.,2017Oct;40(4):1125-1133.doi:10.3892/ijmm.2017.3089.
68.HuX,ChenS,JiaC,XueS,DouC,DaiZ,XuH,SunZ,GengTandCuiH*.Geneexpressionprofilingandanalysesoflongnon-codingRNAsusingRNA-SeqinchickenembryonicfibroblastcellsinfectedbyALVJvirus.ArchivesofVirology,2018Mar;163(3):639-647.doi:10.1007/s00705-017-3659-8.Epub2017Dec2.PMID:29198037
69.ChenS,LiuG,LongM,ZouH,CuiH*.AlphaLipoicAcidAttenuatesCadmium-InducedNephrotoxicityviatheMitochondrialApoptoticPathwaysinRat.JInorgBiochem.2018Apr7;184:19-26.doi:10.1016/j.jinorgbio.2018.04.001.[Epubaheadofprint]PMID:29654931
70.YangYang,MingxuZhou,PhilipR.Hardwidge,HengmiCuiandGuoqiangZhu,IsolationandCharacterizationofN-acylHomoserineLactone-ProducingBacteriaFrom
CattleRumenandSwineIntestines,20188:(5)1-10.
71.HuX,ChenS,CuiIH,WuS,HanX,ZhuW,JiaC,DouC,DaiZ,LiuY,SunZ,YangZ,XueS,ZhuC,XuH,YangY,QiT,OuyangJ,LvD,LiX,GengT,QinAandCuiH*.AnendogenousretroviralelementexertedfunctionofinnateimmunityviaitsderivedantisenselncRNA,Submitted
73.YangZ,ChenS,XueS,LiX,HuJ,SunZ,HuX,GengT,CuiH*.InjectionofanSV40translationalterminatorcausesembryoniclethality:Apossiblezebrafishmodeltoscreenfornon-homologousend-joininginhibitors.Submitted.
74.ZheYang,ShihaoChen,SongleiXue,XinxiuLi,ZhenSun,YuYang1,XumingHu,TuoyuGeng,HengmiCui,GenerationofCas9transgeniczebrafishanditsapplicationinestablishingERV-deficientanimalmodel,submitted
中文文章
1.崔恒宓#,生物新技术与猪品种改良,《当代畜牧》1990年04期:1-2
2.李碧春,经荣斌,龚允陈,林大光,崔恒宓,毛九德,李松,二花脸猪早期胚胎发育的初步研究,《养猪》1993年01期:29-33
3.崔恒宓#,经荣斌,金韶华,毛九德,储新生,唐士余,龙广凤,复合免疫增强剂对仔猪增重及血像和某些免疫学指标的影响,《养猪》1993年01期:5-6
4.经荣斌,崔恒宓,章世元,毛九德,刘铁铮,葛云山,徐晓波,储新生,唐士余,龙广风,商品肉猪快速生长饲养技术试验报告,《养猪》1992年04期:18-19
5.崔恒宓#,葛翔,詹彩娇,丁广新,新配合料与50%“311”料饲喂乳猪对比试验,《畜牧与兽医》1989年06期:247
6.崔恒宓#,正确对待猪的微量元素添加剂,《养猪》1989年02期:10
7.崔恒宓#,猪胚胎死亡原因,《上海畜牧兽医通讯》1990年05期:40-41
8.崔恒宓#,猪胚胎移植技术研究进展,《国外畜牧科技》1987年05期:18-20
9.经荣斌,崔恒宓,太湖猪若干经济性状的研究及利用,《养猪》1991年03期:26-30
10.崔恒宓#,姜曲海母猪性发育过程中血浆雌二醇和孕酮含量变化的研究,《江苏农学院学报》1986,7(8):7-11
11.崔恒宓#,张牧,章世元,周鹂,马德雨,戴金星,哺乳仔猪补料中添加土霉素试验,《上海畜牧兽医通讯》1989,1:18-19
12.崔恒宓#,经荣斌,张牧,张照,香猪生殖器官的发育及血浆雌二醇和睾酮含量变,《中国畜牧杂志》1989年第25卷第5期:13-16
13.崔恒宓*,母猪胚胎死亡原因,《国外畜牧科技》1990年4月第17卷第2期:18-20
14.崔恒宓#,经荣斌,许泉法,吴光华,付堂兵,添加柠檬酸对哺乳仔猪影响的初步研究,《畜牧与兽医》1991年第5期(23卷):201-202
15.张彬,张照,崔恒宓,猪血浆转铁蛋白含量火箭免疫电泳法研究,《湖南农学院学报》1992年12月第18卷第4期:986-990
16.林大光,经荣斌,孙长美,成勇,崔恒宓,李碧春,龚允成,杜淼,邹贤刚,沈三兵,陆德裕,猪的胚胎嵌合试验中若干技术环节的研究,《江苏农学院学报》1992,13(1):19-24
17.张牧,崔恒宓,经荣斌,香猪生长发育规律初探,《上海实验动物科学》1992,12(1):31-33
18.崔恒宓#,张照,严忠慎,周建梁,姚连生,姜曲海母猪发情周期性腺激素及其子宫受体含量的变化规律,《畜牧兽医学报》1992,23(1):8-12
19.汪世新,陈天,经荣斌,崔恒宓,毛九德,新型铜饲料添加剂的合成,《江苏农学院学报》1994年第4卷:66
20.徐万祥,石其贤,崔恒宓,大量分离纯净猪卵透明带的一种简便方法,《生殖与避孕》1994年14卷4期:316-317
21.崔恒宓#,金韶华,毛九德,经荣斌,何良梅,猪脾转移因子的部分生化和免疫性及其应用,《畜牧兽医学报》199425(4):317-322
22.经荣斌,崔恒宓,汪世新,毛九德,张牧,储新生,尤广凤,氨基酸鳌合铜饲喂生长肥育猪的试验,《江苏农学院学报》199516(3):47-50
23.张牧,经荣斌,崔恒宓,香猪的生长发育、繁殖特性及其实验动物化研究,《养猪》1996(2):30-32
24.吴一迁,崔恒宓,基因组印记与癌症,《肿瘤》2002年3月25日第22卷第2期:154-156
25.吴一迁,崔恒宓,万曙光,金晏,罗海涛,许丽,于永梅,钱耕荪,乙肝病毒对DNA修复基因和肝癌发生的作用,《肿瘤》2002年9月25日第22卷第5期:379-381
26.郑明明,胡娅莉,许争峰,王志群,史婷琦,叶晓东,崔恒宓*,实时荧光定量聚合酶链反应技术在产前诊断唐氏综合征中的应用,《中华妇产科杂志》2004年10月第39卷第10期:34-37
27.胡娅莉,徐运,崔恒宓,王心如,胚胎干细胞的研究进展,《医学研究生学报》2005,18(1):77-80。
28.杨薇,陈银海,崔恒宓*,地西他滨和5_阿扎胞苷在癌症研究及临床上的应用,《中国药学杂志》2006,41(21):1601-1605。
回国后
29.刘媛,蒋菁蕊,吴少亘,曹望森,于成功,崔恒宓*,miR-483与结直肠癌关系的研究,《胃肠病学》,2014,19(3):151-155
30.蒋菁蕊,刘媛,吴少亘,曹望森,于成功,崔恒宓*,miR-483-3p抑制DLC1表达促进结直肠癌发生,《胃肠病学》,2014,19(7):394-403。
31.刘洋洋,崔恒宓*,DNA甲基化分析中DNA样本重亚硫酸盐处理转化效率的评估方法,《遗传》2015,37(9):939-944。
32.朱文奇,胡序明,陈世豪,崔恒宓*,禽内源性反转录病毒ALVE表观遗传学分析方法建立及利用,《中国动物传染病学报》2015,23(5):15-20。
33.胡序明,朱文奇,陈世豪,崔恒宓*,禽内源性反转录病毒ALVE1env转录物表达及其调控分析,《中国动物传染病学报》2015,23(5):27-31。
34.沈丹,谢雨琇,李庆平,薛松磊,史云强,王赛赛,陈才,钱跃,高波,崔恒宓,宋成义,多转座子载体的构建及转座特性比较研究,《中国农业科学》2015,48(11):2270-2278。
35.朱文奇,胡序明,陈世豪,刘洋洋,孙振,耿拓宇,宋成义,高波,崔恒宓*,miR-155体外特异性靶向鸡内源性反转录病毒ALVE1env转录物的研究,《畜牧与兽医》,2016,48(5):7-11。
36.田净净,刘洋洋,杨哲,刘菲菲,杨祎擎,韩笑,耿拓宇,高波,宋成义,崔恒宓*,利用CRISPR/Cas9系统高效敲除斑马鱼lncRNA基因启动子区,《农业生物技术学报》,2016,24(5):649-656。
37.胡序明,崔恒宓*,内源性反转录病毒衍生的长非编码RNA的功能,《生命科学》,2016,28(6):695-702。
38.薛松磊,史云强,沈丹,李庆平,宋成义,崔恒宓,高波,转座子介导细胞质显微注射技术的基因转移效率比较,2016,24(1):151-156。
39.徐玉彬,崔恒宓,薛峰,胥广才,张培建,外泌体源性miRNA与结直肠癌诊断的研究进展,《中华普外科手术学杂志:电子版》,2016,10(6):535-537。
40.韩笑,胡序明,袁君婷,吕贝,孙振,陈世豪,耿拓宇,崔恒宓*,鸡巨噬细胞HD11不同转染方法的比较分析,《畜牧与兽医》2017,49(5):72-76。
41.刘斐斐,杨哲,杨祎擎,田净净,崔恒宓*,利用CRISPR/Cas9系统构建绿色荧光转基因斑马鱼,《畜牧与兽医》,2017,49(6):83-87。
42.袁君婷,韩笑,吕贝,胡序明,耿拓宇,崔恒宓*,DNA甲基化抑制剂5-氮-2'脱氧胞苷抗癌新机制初探,《肿瘤》2017,37(3):201-207。
43.吕贝,李华玲,崔恒宓*,反义RNA与肝癌的研究进展,《安徽医科大学学报》2017,52(4):618-621。
44.李华玲,吕贝,袁君婷,韩笑,朱敏,郑丹阳,崔恒宓*,肝癌相关基因MEF2D反义RNA的鉴定及分析,安徽大学学报,2017,41(6):102-108。
45.李富原,赵星,赵盼,刘龙,夏丽丽,崔恒宓,龚道清,梁燕,耿拓宇,填饲和脂肪肝相关因子对鹅长非编码RNA基因(LOC106047490)表达的影响,畜牧与兽医,2017,49(6):60-65。
项目评审
2008          AustrianScienceFund,FWFDerWissenschaftsfonds
2011          ThegrantsoftheItalianMinistryofHealth(MOH)
2009-2011          NIH/NCI,SBIRprogram
2016-现在        国家自然科学基金一审评委
专业会员
2002-         美国人类遗传学协会会员(Member,TheAmericanSocietyofHumanGenetics)
2002-         美国癌症协会会员(Member,AmericanAssociationforCancerResearch)
2004-         美国科学促进会会员(Member,AmericanAssociationfortheAdvancementofSciene)
2016-         江苏省双创人才江苏省双创人才联合会常务理事,生物医学专委会副主任。
杂志编委:
2011-present       OpenMedicineJournal(AssociateEditor)
2009-present       BMCMedicalGenetics(AssociateEditor),
2010-present       WorldJournalofClinicalOncology(EditorialBoardMember)
2011-present       WorldJournalofExperimentalMedicine(EditorialBoardMember)
2011-present       TheScientificWorldJournal(TSWJ)(EditorialBoardMember)

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