个人简历

学习经历
2009-2013本科安徽农业大学动物医学
2013-2016硕士研究生南京农业大学临床兽医学
2016-2019博士研究生南京农业大学临床兽医学
进修情况
2017--2019美国加州大学戴维斯分校新型靶向纳米载药对肿瘤的诊断治疗研究
工作简历
2019.7-至今扬州大学兽医学院讲师

研究领域

中兽医学与中兽药学。主要开展纳米化提高中药多糖脂质体的免疫增强作用和机理的研究，旨在研究开发新型安全有效的免疫佐剂，作为抗原物质的药物递送系统，充分利用国家丰富的中药资源，提高畜禽免疫力，以保障畜牧业的经济效益和可持续健康发展。主要包括中药多糖脂质体的制备工艺优化；中药多糖脂质体的质量检测；中药多糖脂质体的体外免疫活性试验；中药多糖脂质体的体内免疫佐剂活性试验；中药多糖脂质体免疫佐剂活性作用的机理。"科研情况
1、阳离子修饰多糖聚乳酸羟基Z酸共聚物纳米粒的佐剂活性及其作用机理的研究(31872509)
国家自然科学基金面上项目，参与，2019。01-2022.12，排名3/7。
2、多糖脂质立方液晶纳米粒佐剂活性及对树突状细胞作用分子机理的研究(31672596)，
国家自然科学基金面上项目，参与，2017.01-2020。12，排名4/7。"

近期论文

1.RuonanBo,ZhenguangLiu,JingZhang，PengfeiGu，NingOu,YaqinSun,YuanliangFu,JiaguoLiu,DeyunWang*.MechanismofLyciumbarbarumpolysaccharidesliposomesonactivatingmurinedendriticcel1s[J].CarbohydratePolymers,2019，205:540-549.
2.RuonanBo，YaqinSun,ShuzhenZhou,Ning0u,PengfeiGu,ZhenguangLiu,YuanliangHu,JiaguoLiu,DeyunWang*.SimplenanoliposomesencapsulatingLyciumbarbarumpolysaccharidesasadjuvantsimprovehumoralandcellularimmunityinmice[J].InternationalJournalofNanomedicine,2017，12:6289-6301.
3.RuonanBo，SisiZheng，JieXing，LiLuo，YaleNiu,YeeHuang,ZhenguangLiu,YuanliangHu,JiaguoLiu,YiWu,DeyunWang*.TheimmunologicalactivityofLyciumbarbarumpolysaccharidesliposomeinvitroandadjuvanticityagainstPCV2invivo[J].InternationalJournalofBiologicalMacromolecules,2016，85:294--301.
4.RuonanBo,XiaMa，YiboFeng,QianZhu,YeeHuang，ZhenguangLiu,CuiLiu,ZhenzhenGao，YuanliangHu,DeyunWang*.0ptimizationonconditionsofLyciumbarbarumpolysaccharidesliposomebyRSManditseffectsontheperitonealmacrophagesfunction[J].CarbohydratePolymers，2015，117:215-222.
5.XiangdongXue/YeeHuang(co-firstauthor);RuonanBo,BeiJia,HaoWu,YeYuan,ZhonglingWang，ZhaoMa,DiJing，XiaobaoXu,WeiminYu,TzuryinLin,YuanpeiLi*.TrojanHorseNanotheranosticswithDualTransformabilityandMultifunctionalityforHighlyEffectiveCancerTreatment[J].NatureCommunications，2018，9:3653.
6.YeYuan/YixuanHe(co-firstauthor),RuonanBo，ZhaoMa,Zhong1ingWang,LijieDong,Tzu-yinLin,XiangdongXue，YuanpeiLi*.Afacileapproachtofabricateself-assembledmagneticnanotheranosticsfordrugdeliveryandimaging[J].Nanoscale,2018，10(46):21634-21639.
7.YunYu/YuLu(co-firstauthor),RuonanBo,YeeHuang，YuanliangHu,JiaguoLiu,YiWu,YangTao，DeyunWang*.Thepreparationofgypenosidesliposomesanditseffectsontheperitonealmacrophagesfunctioninvitro[J].InternationalJournalofPharmaceutics,2014，460(2):248-254.
8.SisiZheng,LiLuo，RuonanBo,ZhenguangLiu,JieXing，YaleNiu,YuanliangHuJiaguoLiu,DeyunWang*.Evaluationofoptimumconditionsforpachymanencapsulatedinpolynanospheresbyresponsesurfacemethodologyandresultsofarelatedinvitrostudy[J].InternationalJournalofNanomedicine，2016，23:11:4891-4904.
9.YeeHuang，ZhenguangLiu,RuonanBo,JieXing，LiLuo，SisiZheng，YaleNiu,Yuan-liangHu,JiaguoLiu,YiWu,DeyunWang*.TheenhancedimmuneresponseofPCV-2vaccineusingRehmanniaglutinosapolysaccharideliposomeasanadjuvant[J].InternationalJournalofBiologicalMacromolecules.2016,86:929-36.
10.ZhenguangLiu,JieXing,SisiZheng，RuonanBo,LiLuo，YeeHuang，YaleNiu,ZhihuaLi,DeyunWang*,YuanliangHu,JiaguoLiu,YiWu.Ganodermalucidumpolysaccharidesencapsulatedinliposomea8anadjuvanttopromoteTh1-biasimmuneresponse[J].Carbohydratepolymers,2016,142:141-148.
11.JieXing，ZhenguangLiu,YifanHuang,TaoQin,RuonanBo，SisiZheng，LiLuo，YeeHuang，YaleNiu,DeyunWang*.Lentinan-modifiedcarbonnanotubesasanantigendeliverysystemmodulateimmuneresponseinvitroandinvivo[J].ACSAppliedMaterials&Interfaces，2016，8(30):19276-19283.