个人简历

教育经历
2002-2006三峡大学生物学，学士
2006-2009三峡大学生物学，硕士
2009-2013中国科学院遗传与发育生物学研究所，博士
工作经历
2013-今信阳师范学院生命科学学院
教学情况：
主讲《细胞生物学专题》和《分子生物学》等本科生课程。
获资助项目：
参与国家自然科学基金面上项目。

研究领域

1.乳腺癌干细胞三维培养体系建立；
2.注射型胶原支架材料的制备；
3.有序性胶原支架材料应用于脊髓损伤修复。

近期论文

1.ZhengquanHe,LeiChen,WeiYao,JianwuDai.RecentProgressinCucumber(Cucumissativus)Transformation.TransgenicPlantJournal,2008,2:39-44(co-first-author).
2.LeiChen,ZhengquanHe,BingChen,YannanZhao,WenjieSun,ZhifengXiao,JingZhang,MaojinYang,ZhiyingGao,andJianwuDa.DirectChemicalCross-LinkingofPlatelet-DerivedGrowthFactor-BBtotheDemineralizedBoneMatrixImprovesCellularizationandVascularization.Biomacromolecules,2009,10,3193–3198(IF=5.479).
3.LeiChen,ZhengquanHe,BingChen,MaojinYang,YannanZhao,WenjieSun,ZhifengXiao,JingZhang,JianwuDai.LoadingofVEGFtotheheparincross-linkeddemineralizedbonematriximprovesvascularizationofthescaffold.JMaterSci:MaterMed,2010,21:309–317(IF=2.316).
4.LeiChen,ZhifengXiao,YueMeng,YannanZhao,JinHan,GuannanSu,BingChen,JianwuDai.TheenhancementofcancerstemcellpropertiesofMCF-7cellsin3Dcollagenscaffoldsformodelingofcancerandanti-cancerdrugs.Biomaterials,2012,33:1437-1444(IF=7.404).
5.陈磊，何正权，杨晔，姚伟.植物遗传转化的正向选择标记.中国生物工程杂志，2008，28(6s)：283-288.
6.JinHan,ZhifengXiao,LeiChen,BingChen,XiaoranLi,SufangHan,YannanZhao,JianwuDai.Maintenanceoftheself-renewalpropertiesofneuralprogenitorcellsculturedinthree-dimensionalcollagenscaffoldsbytheREDD1-mTORsignalpathway.Biomaterials.2013,34(8):1921-8.
7.QinShi,YangLi,JieSun,HuaZhang,LeiChen,BingChen,HuilinYang,ZhaoxuWang.Theosteogenesisofbacterialcellulosescaffoldloadedwithbonemorphogeneticprotein-2.Biomaterials.2012,33(28):6644–6649
8.QianqianHan,WeiJin,ZhifengXiao,HongbinNi,JinhuanWang,JieKong,JunWu,WeibangLiang,LeiChen,YannanZhao,BingChen,JianwuDai.ThepromotionofneuralregenerationinanextremeratspinalcordinjurymodelusingacollagenscaffoldcontainingacollagenbindingneuroprotectiveproteinandanEGFRneutralizingantibody.Biomaterials.2010,31(35):9212–9220
9.QifenHe,YannanZhao,BingChen,ZhifengXiao,JingZhang,LeiChen,WeiChen,FeilongDeng,JianwuDai.Improvedcellularizationandangiogenesisusingcollagenscaffoldschemicallyconjugatedwithvascularendothelialgrowthfactor.ActaBiomaterialia.2011,7(3):1084–1093
10.GuannanSu,YannanZhao,JianshuWei,JinHan,LeiChen,ZhifengXiao,BingChen,JianwuDai.Theeffectofforcedgrowthofcellsinto3Dspheresusinglowattachmentsurfacesontheacquisitionofstemnessproperties.Biomaterials.2013,34(13):3215–3222
11.SufangHan,YannanZhao,ZhifengXiao,JinHan,BingChen,LeiChen,JianwuDai.TheThree-DimensionalCollagenScaffoldImprovestheStemnessofRatBoneMarrowMesenchymalStemCells.JournalofGeneticsandGenomics.2012,39(12):633–641
12.XiaoranLi,ZhifengXiao,JinHan,LeiChen,HanshanXiao,FukaiMa,XianglinHou,XingLi,JieSun,WenyongDing,YannanZhao,BingChen,JianwuDai.PromotionofneuronaldifferentiationofneuralprogenitorcellsbyusingEGFRantibodyfunctionalizedcollagenscaffoldsforspinalcordinjuryrepair.Biomaterials,2013,34(21):5107–5116.
13.JianGuan,ZhaohuiZhu,RobertChunhuaZhao,ZhifengXiao,ChenxiWu,QinHan,LeiChen,WeiminTong,JinZhang,QianqianHan,JunGao,MingFeng,XinjieBao,JianwuDai,RenzhiWang.Transplantationofhumanmesenchymalstemcellsloadedoncollagenscaffoldsforthetreatmentoftraumaticbraininjuryinrats.Biomaterials,2013,34(24):5937–5946.
14.JinHan,LeiChen,GuanzhengLuo,BinDai,XiujieWang,JianwuDai.Three-dimensionalculturemaypromotecellreprogramming.Organogenesis,2013，9(2):118-120
15.GuannanSu,YannanZhao,JianshuWei,ZhifengXiao,BingChen,JinHan,LeiChen,JianGuan,RenzhiWang,QunDong,JianwuDai.Directconversionoffibroblastsintoneuralprogenitor-likecellsbyforcedgrowthinto3Dspheresonlowattachmentsurfaces.Biomaterials,2013,34(24):5897–5906