个人简历

1983.01-，本科毕业于山东大学医学院临床医学专业，硕士毕业于山东大学医学院病理学专业，2015年获得瑞典卡罗林斯卡医学院博士学位。2018年被授予新乡医学院“太行青年学者”称号。

研究领域

肿瘤学，主要从事乳腺癌发病机制的相关研究

近期论文

Costa TDF, Zhuang T, Lorent J, Turco E, Olofsson H, Masia-Balague M, Zhao M, Rabieifar P, Robertson N, Kuiper R, Sjölund J, Spiess M, Hernández-Varas P, Rabenhorst U, Roswall P, Ma R, Gong X, Hartman J, Pietras K, Adams PD, Defilippi P, Strömblad S. PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.Nat Commun. 2019 Aug 9;10(1):3589.IF=11.878
Xue M, Zhang K, Mu K, Xu J, Yang H, Liu Y, Wang B, Wang Z, Li Z, Kong Q, Li X*, Wang H*, Zhu J*, Zhuang T*. Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56. Oncogenesis. 2019 Apr 18;8(5):30. IF=5.995
Hou Y, Li X, Li Q, Xu J, Yang H, Xue M, Niu G, Zhuo S, Mu K, Wu G, Li X*, Wang H*, Zhu J*, Zhuang T*. STAT1 facilitates oestrogen receptor α transcription and stimulates breast cancer cell proliferation.J Cell Mol Med. 2018 Dec;22(12):6077-6086.IF=4.658
Liu Z, Zhang J, Xu J, Yang H, Li X, Hou Y, Zhao Y, Xue M, Wang B, Yu N, Yu S, Niu G, Wu G, Li X*, Wang H*, Zhu J*, Zhuang T*. RNF168 facilitates oestrogen receptor ɑ transcription and drives breast cancer proliferation.J Cell Mol Med. 2018 Sep;22(9):4161-4170.IF=4.658
Yang H, Yu N, Xu J, Ding X, Deng W, Wu G, Li X, Hou Y, Liu Z, Zhao Y, Xue M, Yu S, Wang B, Li X, Niu G, Wang H*, Zhu J*, Zhuang T*. SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells.J Exp Clin Cancer Res. 2018 Feb 12;37(1):24.IF=5.646
Zhuang T#, Yu S#, Zhang L#, Yang H, Li X, Hou Y, Liu Z, Shi Y, Wang W, Yu N, Li A, Li X, Li X, Niu G, Xu J, Hasni MS, Mu K, Wang H, Zhu J. SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation.Oncotarget. 2017 Aug 19;8(44):77137-77151.
Yang H, Yu S, Wang W, Li X, Hou Y, Liu Z, Shi Y, Mu K, Niu G, Xu J, Wang H*, Zhu J*, Zhuang T*. SHARPIN Facilitates p53 Degradation in Breast Cancer Cells.Neoplasia. 2017 Feb;19(2):84-92.IF=4.994
Zhuang T#, Zhu J#, Li Z, Lorent J, Zhao C, Dahlman-Wright K, Strömblad S. p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells.Oncotarget. 2015 Dec 22;6(41):43853-68.