个人简历

1979.02-，2011年于北京协和医学院基础医学研究所取得博士学位，研究方向为真核基因表达调控。2012年加拿大Dalhousie University进行博士后研究工作。荣获河南省高校科技创新人才，河南省教育厅学术技术带头人，河南省高校青年骨干教师等称号。主持国家自然科学基金（31301135）、河南省科技创新人才项目（17HASTIT047）、河南省自然科学基金面上项目（162300410226）、河南省科技攻关计划项目（172102310583）、河南省教育厅重点项目（14B320015）等多项科研项目，并获得河南省博士后科研项目资助二等奖。迄今为止在国内外学术刊物发表论文30篇（其中SCI收录的论文12篇）；参编专著2部，授权发明专利2项。

研究领域

1、髓系细胞造血分化相关基因表达调控
2、精神疾病相关non-coding RNA诊断标志物的筛选
3、结核病及并发症分子遗传及机制研究

近期论文

Hai-chuan Yu, Jiao Wu, Hong-xing Zhang, Gao-li Zhang, Juan Sui, Wen-wen Tong, Ting-ting Qiao, Xin-ya Zhang, Li-li Nie, Ju-hong Duan, Li-rong Zhang, Lu-xian Lv. Alterations of miR-132 are novel diagnostic biomarkers in peripheral blood of schizophrenia patients. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Dec 3;63:23-9. doi: 10.1016/j.pnpbp.2015.05.007.
Hai-chuan Yu, Jiao Wu, Hong-xing Zhang, Hai-san Zhang, Ting-ting Qiao, Ji-Xia Zhang, Gao-li Zhang, Juan Sui, Li-wei Li, Li-rong Zhang, Lu-xian Lv. Antidepressant-like and antioxidative efficacy of Campsis grandiflora flower. J Pharm Pharmacol. 2015 Dec;67(12):1705-15. doi: 10.1111/jphp.12466.
Jiao Wu#, Haichuan Yu#, Haofu Dai, Wenli Mei, Xin Huang, Shuifang Zhu, and Ming Peng. Metabolite profiles of rice cultivars containing bacterial blight-resistant genes are distinctive from susceptible rice. Acta Biochimical et Biophysica Sinica 2012, 44: 650–659.
Hai-Chuan Yu, Hua-lu Zhao Jun-Wu Zhang. Eos Negatively Regulates Human c-globin Gene Transcription during Erythroid Differentiation. PLoS ONE 2011, 6(7): e22907. doi:10.1371/journal.pone.0022907.
Hai-Chuan Yu, Jiao WU, Nan-Fei XU, Ming PENG. The Role of F-box Proteins in Plant Hormone Signaling Responses. Acta Biochimical et Biophysica Sinica 2007: 39(12) 915-922.
Zhang H, Wang C, Jiang T, Guo H, Wang G, Cai X, Yang L, Zhang Y, Yu H, Wang H, Jiang K. Microtubule-targetable fluorescent probe: site-specific detection and super-resolution imaging of ultratrace tubulin in microtubules of living cancer cells. Anal Chem. 2015 May 19;87(10):5216-22. doi: 10.1021/acs.analchem.5b01089. Epub 2015 May 6.
Qi Cao, Kexin Zhao, Xi Zoë Zhong, Yuanjie Zou, Haichuan Yu, Peng Huang, Tian-Le Xu, and Xian-Ping Dong. SLC17A9 Protein Functions as a Lysosomal ATP Transporter and Regulates Cell Viability. J Biol Chem 2014, 289（33）:23189-23199.
Yan-Ni Ma, Ming-Tai Chen, Zhi-Kui Wu, Hua-Lu Zhao, Hai-Chuan Yu, Jia Yu & Jun-Wu Zhang. Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes. Mol Cell Biochem 2013, 382:127-136, DOI 10.1007/s11010-013-1726-3.
Yan-Ni Ma, Xin Zhang, Hai-Chuan Yu, Jun-Wu Zhang. CTD small phosphatase like 2 (CTDSPL2) can increase epsilon- and gamma-globin gene expression in K562 cells and CD34+ cells derived from umbilical cord blood. BMC Cell Biology 2010, 11:75 doi:10.1186/1471-2121-11-75.
Chunqiang Li, Baibi Zhu, Hong Chen, Zhixin Liu, Baiming Cui, Jingrui Wu, Bin Li, Haichuan Yu, Ming Peng.The Relationship between the Skeletonema Costatum Red tide and Environmental Factors in Hongsha Bay of Sanya, South China Sea. Journal of Coastal Research 2009, 25(3): 651–658.