个人简历

高峰, 男，博士，教授，博士研究生导师，西南交通大学生命科学与工程学院副院长，西南交通大学医学院副院长，四川省学术技术带头人后备人选，四川省药学类专业教学指导委员会委员，《天然产物研究与开发》和《生物学杂志》编委。2002年毕业于四川大学华西药学院药学专业，获药学学士学位，2005年毕业于四川大学华西药学院，获药物化学硕士学位。2009年在四川大学华西药学院获天然药物化学博士学位，同年进入四川农业大学农学院中草药栽培与鉴定教研室，从事科研及教学工作，2013年8月至2014年8月在美国宾夕法尼亚大学化学系访学，2016年9月进入西南交通大学生命科学与工程学院。\r
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教育经历\r
2005.9-2009.6 四川大学 | 药物化学 | 博士研究生毕业 | 理学博士学位\r
2002.9-2005.6 四川大学 | 药物化学 | 硕士研究生毕业 | 理学硕士学位\r
1998.9-2002.7 四川大学 | 药学 | 大学本科毕业 | 理学学士学位\r
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工作经历\r
生命科学与工程学院 | 西南交通大学 \r
四川农业大学

研究领域

"""""[1]天然抗癌药物的发现及其结构修饰\r
[2]AI指导的小分子药物的发现、合成及作用机制\r
[3]金属催化的小分子药物Late-stage修饰及活性筛选"

近期论文

Bo Yin, Yu-Feng Du, Yan-Zuo Chen, Xiaohuan Li, Dong-Mei Fang, Feng Gao*, Palladium-catalyzed direct deprotonative arylation of 2-pyridylacetonitriles: Facile synthesis of alpha-aryl-2-pyridylacetonitrile, Tetrahedron Lett., 2020, 61, 152534.\r
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Lin-Xi Wan, Ji-Fa Zhang, Yong-Qi Zhen, Lan Zhang, Xiaohuan Li, Feng Gao*, and Xian-Li Zhou*, Isolation, Structure Elucidation, Semi-Synthesis, and Structural Modification of C19-Diterpenoid Alkaloids from Aconitum apetalum and Their Neuroprotective Activities, J. Nat. Prod., 2021, 84, 1067−1077.\r
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Lin-Xi Wan, Yong-Qi Zhe, Zhen-Xiang He, Yang Zhang, Lan Zhang, Xiaohuan Li, Feng Gao*, and Xian-Li Zhou, Late-stage modification of medicine: Pb-catalyzed direct synthesis and biological evaluation of N-aryltacrine derivatives, ACS Omega, 2021, 6, 9960−9972.\r
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Jing Lu, Jin-Pu Xu, Xiao-Huan Li, Chun-Gu Zhang, Feng Gao*, Three new C19-diterpenoid alkaloids from Aconitum novoluridum, Chem. Pharm. Bull., 2021, 69, 811–816.\r
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Lin-Xi Wan, Shi-Xing Miao, Zhen-Xiang He, Xiaohuan Li, Xian-Li Zhou, Feng Gao*, Pd-Catalyzed Direct Modification of an Anti-Alzheimers Disease Drug: Synthesis and Biological Evaluation of Aryl Donepezil Analogues, ACS Omega, 2021, 6, 36, 23347–23354\r
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Shi-Xing Miao, Lin-Xi Wan, Zhen-Xiang He, Xian-Li Zhou, Xiaohuan Li, and Feng Gao*, Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer’s Disease Drug: Synthesis and Biological Evaluation of N‑Aryl Huperzine A Analogues, J. Nat. Prod., 2021, 84, 2374−2379.\r
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Yao Xiao, Neng Wang, Lin-Xi Wan, Xiao-Huan Li, Xian-Li Zhou, Feng Gao*, Iron-Catalyzed Skeletal Conversion of Lathyrane to Premyrsinane Euphorbia Diterpenes and Their Cytotoxic Activities, J. Nat. Prod., 2021, 84, 1838−1842\r
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Ji-Fa Zhang, Lin Chen, Shuai Huang, Lian-Hai Shan, Feng Gao,* and Xian-Li Zhou*, Diterpenoid Alkaloids from Two Aconitum Species with Antifeedant Activity against Spodoptera exigua, J. Nat. Prod., 2017, 80, 3136–3142. \r
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Pei-Geng Xiao*, Feng-Peng Wang, Feng Gao, Lu-Ping Yan, Dong-Lin Chen, Yong Liu, A pharmacophylogenetic study of Aconitum L. (Ranunculaceae) from China, Acta Phytotaxonomic Sinica, 2006, 44, 1-46. (第五届中国科协期刊优秀学术论文奖)\r
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Yan-Nan Cao, Xin-Chuan Tian, Xing-Xiu Chen, Yun-Xin Yao, Feng Gao*, Xian-Li Zhou*, Rapid Ligand-Free Base-Accelerated Copper-Catalyzed Homo-coupling Reaction of Arylboronic Acids, Synlett, 2017, 28, 601-606.\r
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Nan-Nan Jia, Xin-Chuan Tian, Xiao-Xia Qu, Xing-Xiu Chen, Ya-Nan Cao, Yun-Xin Yao, Feng Gao*, Xian-Li Zhou, Copper-catalyzed Direct 2-Arylation of Benzoxazoles and Benzoimidazoles with Aryl Bromides and Cytotoxicity of Products, Scientific Reports, 2017, 7, 43758.\r
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Tianyi Liu, Annemarie L. Exarhos, Ethan C. Alguire, Feng Gao, Elmira Salami-Ranjbaran, Kevin Cheng, Tiezheng Jia, Joseph E. Subotnik, Patrick J. Walsh, James M. Kikkawa, and Zahra Fakhraai, Phys. Rev. Lett., 2017, 119, 095502.\r
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Jiadi Zhang, Sheng-Chun Sha, Ana Bellomo, Nisalak, Trongsiriwat, Feng Gao, Neil Tomson*, Patrick J. Walsh*, Positional Selectivity in C–H Functionalizations of 2-Benzyl Furans with Bimetallic Catalysts, J. Am. Chem. Soc., 2016, 138, 4260-4266\r
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Guan Wen, Xiao-Xia Qu, Dan Wang, Xing-Xiu Chen, Xing Chuan Tian, Feng Gao*, Xian-Li Zhou*, Recent advances in design, synthesis and bioactivity of paclitaxel-mimics, Fitoterapia, 2016, 110, 26-37.\r
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Zhong-Sheng Wang, Wei Chen, Hai-Yue Jiang, Feng Gao∗, Xian Li Zhou∗, Semi-synthesis and structural elucidation of brevicanines A–D, four new C19-diterpenoid alkaloids with rotameric phenomenon from Aconitum brevicalcaratum, Fitoterapia, 2019, 134, 404-410.\r
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Jia-Xi Wang, Ling-Li Zheng, Feng Gao∗, Xian Li Zhou∗, Lewis acid-mediated skeleton transformation of Euphorbia diterpenes: From lathyrane to euphoractane and myrsinane, Fitoterapia, 2019, 133, 212-218.\r
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Tianyi Liu, Kevin Cheng, Elmira Salami-Ranjbaran, Feng Gao, Chen Li, Xiao Tong, Yi-Chih Lin, Yue Zhang, William Zhang, Lindsey Klinge, Patrick J. Walsh*, and Zahra Fakhraai*, The effect of chemical structure on the stability of physical vapor deposited glasses of 1,3,5-triarylbenzene, J. Chem. Phys., 2015, 143, 084506.\r
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Ling Li Zheng, Dan Wang, Yuan Yuan Li, Hong Yan Peng, Ming Yong Yuan, Feng Gao*, Ultrasound assisted extraction of total flavonoids from Aconitum gymnandrum, Pharmacog., Mag., 2014, 10, S141-146.