个人简历

2021-now Professor, Department of Chemistry, and School of Life Sciences (by courtesy), the Chinese University of Hong Kong, China\r
2015-2021 Associate Professor, the Chinese University of Hong Kong\r
2009-2014 Assistant Professor, the Chinese University of Hong Kong\r
2007-2008 Postdoc (Advisor: Linda Hsieh-Wilson) California Institute of Technology/Howard Hughes Medical Institute, USA\r
2002-2006 PhD. (Advisor: Prof. Chaitan Khosla) Stanford University, USA\r
1999-2002 M.Sc. (Advisor: Prof. Wenxia Tang) Nanjing University, China\r
1995-1999 B.Sc. Department for Intensive Instruction, Nanjing University, China

研究领域

"""""Chemical biology\r
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Protein reactions\r
Site-selective protein reactions (cysteine

近期论文

Liang, Y.†; Iqbal, Z.†; Lu, J.; Wang, J.; Zhang, H.; Chen, X.; Duan, L.*; Xia, J.* Cell-Derived Nanovesicle-Mediated Drug Delivery to the Brain: Principles and Strategies for Vesicle Engineering. Molecular Therapy 2022 Accepted. (Review)\r
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Yuan, D.†; Zhang, Y.†; Lim, K. H.; Leung, S. K. P.; Yang, X.; Liang, Y.; Lau, W. C. Y.; Chow, K. T.*; Xia, J.* Site-Selective Lysine Acetylation of Human Immunoglobulin G for Immunoliposomes and Bispecific Antibody Complexes. J. Am. Chem. Soc. Accepted.\r
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Wang, C.; Li, Y.; Liu, L.; Liu, M.; Chen, X.; Zhou, S.; Cui, P.; Du, X.; Qiu, L.; Wang, J.*; Jiang, P.*; Xia, J.* Antimicrobial Nanozyme-Enzyme Complex Catalyzing Cascade Reaction of Glucose to Hydroxyl Radical to Combat Bacterial Infection Journal of Drug Delivery Science and Technology, 2022, accepted.\r
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Liang, Y.; Igbal, Z.; Wang, J.; Xu, L.; Xu, X.; Ouyang, K.; Zhang, H.; Lu, J.; Duan, L.; Xia, J.* Cell-Derived Extracellular Vesicles for CRISPR/Cas9 Delivery: Engineering Strategies for Cargo Packaging and Loading Biomaterials Science, 2022, 10, 4095 – 4106.\r
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Shinge, S. A. U.; Xiao, Y.; Xia, J.; Liang, Y.; Duan, L. New insights of engineering plant exosome-like nanovesicles as a nanoplatform for therapeutics and drug delivery Extracellular Vesicles and Circulating Nucleic Acids 2022, 3, 150-162.\r
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Wei, Q.; Wang, Y.; Liu, Z.; Liu, M.; Cao, S.; Jiang, H.; Xia, J.* Multienzyme Assembly on Caveolar Membranes In Cellulo ACS Catalysis 2022, 12, 8372-8379.\r
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Lei, X.; Li, M.; Wang, C.; Cui, P.; Qiu, L.; Zhou, S.; Jiang, P.; Li, H.; Zhao, D.; Ni, X.; Wang, J.; Xia, J.* Degradable Microneedle Patches Loaded with Antibacterial Gelatin Nanoparticles to Treat Staphylococcal Infection-Induced Chronic Wounds International Journal of Biological Macromolecules, 2022, 217, 55-65.\r
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Liang, Y.; Xu, X.; Xu, L.; Ouyang, K.; Zhang, H.; Duan, L.; Xia, J.* Chondrocyte-Specific Genome Editing Enabled by Hybrid Exosomes for Osteoarthritis Treatment Theranostics, 2022, 12, 4866-4878.\r
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Wang, Y.†; Liu, M.†; Wei, Q.; Wu, W.; He, Y.; Gao, J.; Zhou, R.; Jiang, L.; Qu, J.; Xia, J.* Phase-Separated Multienzyme Compartmentalization for Terpene Biosynthesis in a Prokaryote Angew. Chem. Int. Ed. 2022, e202203909.\r
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Huang, J.; Liu, F.; Su, H.; Xiong, J.; Yang, L.; Xia, J.; Liang, Y.* Advanced Nanocomposite Hydrogels for Cartilage Tissue Engineering Gels 2022, 8, 138.\r
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Huang, J.; Lei, L.; Huang, Z.; Rong, Z.; Li, H.; Xie, Y.; Duan, L.; Xiong, J.; Wang, D.; Zhu, S.; Liang, Y.*; Wang, J.*; Xia, J.* Gelatin – Recombinant Type III Collagen Hydrogel to Promote Wound Healing Int. J. Bioprinting 2022, 8, 517.\r
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Wang, X.; Qiu, L.; Wang, C.; Gao, Z.; Zhou, S.; Cui, P.; Jiang, P.; Hu, H.; Ni, X.*; Du, X.; Wang, J.*; Xia, J.* “Nanodot–doped peptide hydrogel for antibacterial phototherapy and wound healing” Biomater. Sci accepted\r
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Xu, L.; Liang, Y.; Xu, X.; Xia, J.; Wen, C.; Zhang, P.; Duan, L.* “Blood cell-derived extracellular vesicles: diagnostic biomarkers and smart delivery systems” Bioengineered 2021, doi.org/10.1080/21655979.2021.1982320.\r
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Huang, J.; Zhang, J.; Xiong, J.; Sun, S.; Xia, J.*; Yang, L.*; Liang, Y.* “Stem Cell-Derived Nanovesicles: A Novel Cell-Free Therapy for Wound Healing” Stem Cells International 2021, doi.org/10.1155/2021/1285087.\r
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So, W. H#.; Bao, Y.#; Chen, X.; Xia, J.* “On-Resin Ugi Reaction for C-Terminally Modified and Head-to-Tail Cyclized Antibacterial Peptides” Org. Lett. 2021, 23, 8277–8281. （# equal contribution)\r
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Bao, Y.; Qiu, J.; Xia, J.* “Covalent Reactive Peptides to Block Protein – Protein Interactions and Inhibit Microbe-Host Interaction” Methods in Molecular Biology 2021 in press.\r
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Duan, L.; Ouyang, K.; Wang, J.; Xu, L.; Xu, X.; Wen, C.; Xie, Y.; Liang, Y.*; Xia, J.* “Exosomes as Targeted Delivery Platform of CRISPR/Cas9 for Therapeutic Genome Editing” ChemBioChem 2021, doi.org/10.1002/cbic.202100359.\r
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Chen, X.; Liu, M.; Zhang, P.; Xu, M.; Yuan, W.; Bian, L.; Liu, Y. Xia, J.*; Leung, S. S. Y.* “Phage-Derived Depolymerase as an Antibiotic Adjuvant Against Multidrug-Resistant Acinetobacter Baumannii” ACS Infectious Diseases, revised.\r
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Wang, R.; Liu, M.; Wang, H.; Xia, J.; Li, H.* “GB Tags: Small Covalent Peptide Tags Based on Protein Fragment Reconstitution” Bioconjugate Chem. 2021, 32, 1926-1934.\r
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Ho, M. K. Y.; Zhang, P.; Chen, X.; Xia, J.*; Leung, S. S. Y.* “Bacteriophage endolysins against gram-positive bacteria, an overview on the clinical development and recent advances on the delivery and formulation strategies” Critical Reviews in Microbiology, 2021, 1-24.\r
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