个人简历

吕爱平，香港浸会大学中医药学院院长丶讲座教授，香港浸会大学岑尧宽岑碧泉纪念癌症炎症研究中心主任丶香港浸会大学整合生物信息医学和转化科学研究所所长丶香港浸会大学疼痛联合研究中心主任丶中国中医科学院首席研究员。是国家杰出青年基金获得者。是国家自然科学基金委员会医学部谘询委员会委员, 国家药典委员会委员，全国科学技术名词审定委员会中医名词术语委员会副主任委员, 国际标准化组织-TC249 中方Mirror Committee 主席。曾任中国中医科学院临床基础研究所常务副所长（法人代表）丶中国中医研究院基础理论研究所所长丶江西本草天工科技有限公司（中药固体制剂制造技术国家工程研究中心）董事长。

研究领域

"""""长期从事中医证候分类治疗类风湿关节炎的基础和新药研发工作"

近期论文

Li D, Liu J, Guo B, Liang C, Dang L, Lu C, He X, Cheung HY, Xu L, Lu C, He B, Liu B, Shaikh AB, Li F, Wang L, Yang Z, Au DW, Peng S, Zhang Z, Zhang BT, Pan X, Qian A, Shang P, Xiao L, Jiang B, Wong CK, Xu J, Bian Z, Liang Z, Guo DA, Zhu H, Tan W, Lu A, Zhang G. Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation. Nat Commun. 2016:7:10872.\r
Yao H, Jiang F, Lu A, Zhang G. Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs). Int J Mol Sci. 2016: 17(2). pii: E194.\r
Zhou W, Wang Y, Lu A, Zhang G. Systems Pharmacology in Small Molecular Drug Discovery. Int J Mol Sci. 2016:17(2). pii: E246.\r
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Yu Y, Liang C, Lv Q, Li D, Xu X, Liu B, Lu A, Zhang G. Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers. Int J Mol Sci. 2016:11;17(3). pii: E358.\r
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Wang C, Liu B, Xu X, Zhuang B, Li H, Yin J, Cong M, Xu W,, Lu A. (2016) Toward targeted therapy in chemotherapy-resistant pancreatic cancer with a smart triptolide nanomedicine. Oncotarget. [Epub ahead of print]\r
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Tan Y, Liu X, Zhou K, He X, Lu C, He B, Niu X, Xiao C, Xu G, Bian Z, Zu X, Zhang G, Zhang W, Lu A. The Potential Biomarkers to Identify the Development of Steatosis in Hyperuricemia. PLoS One 2016:11(2):e0149043.\r
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Yu Y, Liang C, Lv Q, Li D, Xu X, Liu B, Lu A, Zhang G. Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers. Int J Mol Sci. 2016 Mar 11;17(3).\r
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Gong Y, Lin Y, Zhao N, He X, Lu A, Wei W, Jiang M. The Th17/Treg Immune Imbalance in Ulcerative Colitis Disease in a Chinese Han Population. Mediators Inflamm. 2016;2016:7089137.\r
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Ning Z, Liu Z, Song Z, Zhao S, Dong Y, Zeng H, Shu Y, Lu C, Liu Y, Lu A. A single marker choice strategy in simultaneous characterization and quantification of multiple components by rapid resolution liquid chromatography coupled with triple quadrupole tandem mass spectrometry (RRLC-QqQ-MS). J Pharm Biomed Anal. 2016 Mar 3;124:174-188.\r
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Zhang B, Fu Y, Huang C, Zheng C, Wu Z, Zhang W, Yang X, Gong F, Li Y, Chen X, Gao S, Chen X, Li Y, Lu A, Wang Y. New strategy for drug discovery by large-scale association analysis of molecular networks of different species. Sci Rep. 2016 Feb 25;6:21872.\r
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Zhou W, Wang Y, Lu A, Zhang G. Systems Pharmacology in Small Molecular Drug Discovery. Int J Mol Sci. 2016 Feb 18;17(2).\r
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Tan Y, Liu X, Zhou K, He X, Lu C, He B, Niu X, Xiao C, Xu G, Bian Z, Zu X, Zhang G, Zhang W, Lu A. The Potential Biomarkers to Identify the Development of Steatosis in Hyperuricemia. PLoS One. 2016 Feb 18;11(2):e0149043. \r
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Wang C, Liu B, Xu X, Zhuang B, Li H, Yin J, Cong M, Xu W, Lu A. Toward targeted therapy in hemotherapy-resistant pancreatic cancer with a smart triptolide nanomedicine. Oncotarget. 2016 Jan 29. doi: 10.18632/oncotarget.7073. [Epub ahead of print]\r
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Jiang M, Zha Q, Zhang C, Lu C, Yan X, Zhu W, Liu W, Tu S, Hou L, Wang C, Zhang W, Liang Q, Fan B, Yu J, Zhang W, Liu X, Yang J, He X, Li L, Niu X, Liu Y, Guo H, He B, Zhang G, Bian Z, Lu A. Predicting and verifying outcome of Tripterygium wilfordii Hook F. based therapy in rheumatoid arthritis: from open to double-blinded randomized trial. Sci Rep. 2015 Apr 15;5:9700.\r
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Zhang X, Ng HL, Lu A, Lin C, Zhou L, Lin G, Zhang Y, Yang Z, Zhang H. Drug delivery system targeting advanced hepatocellular carcinoma: Current and future. Nanomedicine. 2016 Jan 7. pii: S1549-9634(16)00005-8. doi: 10.1016/j.nano.2015.12.381. [Epub ahead of print]\r
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Li Y, Wang J, Xiao Y, Wang Y, Chen S, Yang Y, Lu A, Zhang S. A systems pharmacology approach to investigate the mechanisms of action of Semen Strychni and Tripterygium wilfordii Hook F for treatment of rheumatoid arthritis. J Ethnopharmacol. 2015:175:301-314.\r
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Guo J, Qin S, Liang J, Lin T, Si L, Chen X, Chi Z, Cui C, Du N, Fan Y, Gu K, Li F, Li J, Li Y, Liang H, Liu J, Lu M, Lu A, Nan K, Niu X, Pan H, Ren G, Ren X, Shu Y, Song X, Tao M, Wang B, Wei W, Wu D, Wu L, Wu A, Xu X, Zhang J, Zhang X, Zhang Y, Zhu H; written; Chinese Society of Clinical Oncology (CSCO) Melanoma Panel. Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition). Ann Transl Med. 2015 Dec;3(21):322.\r
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Zhao N, Li J, Li L, Niu XY, Jiang M, He XJ, Bian ZX, Zhang G, Lu A. Molecular network-based analysis of guizhi-shaoyao-zhimu decoction, a TCM herbal formula, for treatment of diabetic peripheral neuropathy. Acta Pharmacol Sin. 2015 Jun;36(6):716-723.\r
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Zhang B, Lu C, Bai M, He X, Tan Y, Bian Y, Xiao C, Zhang G, Lu A, Li S. (2015) Tetramethylpyrazine identified by a network pharmacology approach amel iorates methotrexate-induced oxidative organ injury. J Ethnopharmacol.175:638-647.\r
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Lin C, Ng HL, Pan W, Chen H, Zhang G, Bian Z, Lu A, Yang Z. Exploring Different Strategies for Efficient Delivery of Colorectal Cancer Therapy. Int J Mol Sci. 2015 Nov 11;16(11):26936-52.\r
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Fatima S, Shi X, Lin Z, Chen GQ, Pan XH, Wu JC, Ho JW, Lee NP, Gao H, Zhang G, Lu A, Bian ZX. 5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing β-catenin. Mol Oncol. 2016 Feb;10(2):195-212.\r
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Jiang F, Liu B, Lu J, Li F, Li D, Liang C, Dang L, Liu J, He B, Badshah SA, Lu C, He X, Guo B, Zhang XB, Tan W, Lu A, Zhang G. Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems. Int J Mol Sci. 2015 Oct 9;16(10):23784-822.\r
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Zhang B, Lu C, Bai M, He X, Tan Y, Bian Y, Xiao C, Zhang G, Lu A, Li S. Tetramethylpyrazine identified by a network pharmacology approach ameliorates methotrexate-induced oxidative organ injury. J Ethnopharmacol. 2015 Dec 4;175:638-47.\r
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Xu S, Zhang T, Kompella SN, Yan M, Lu A, Wang Y, Shao X, Chi C, Adams DJ, Ding J, Wang C. Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Sci Rep. 2015 Sep 23;5:14261.\r
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Niu X, Lu C, Xiao C, Ge N, Jiang M, Li L, Bian Y, Xu G, Bian Z, Zhang G, Lu A. The Crosstalk of Pathways Involved in Immune Response Maybe the Shared Molecular Basis of Rheumatoid Arthritis and Type 2 Diabetes. PLoS One. 2015:10(8):e0134990.\r
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Li Y, Wang J, Xiao Y, Wang Y, Chen S, Yang Y, Lu A, Zhang S. A systems pharmacology approach to investigate the mechanisms of action of Semen Strychni and Tripterygium wilfordii Hook F for treatment of rheumatoid arthritis. J Ethnopharmacol. 2015 Dec 4;175:301-14.\r
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Li P, Huang C, Fu Y, Wang J, Wu Z, Ru J, Zheng C, Guo Z, Chen X, Zhou W, Zhang W, Li Y, Chen J, Lu A, Wang Y. Large-scale exploration and analysis of drug combinations. Bioinformatics. 2015:31(12):2007-2016.