赵宝贻
近期热点
资料介绍
个人简历
2001-2007-2007-2011 Assistant Professor, Department of Chemistry Associate Professor, Department of Chemistry\r2011-present Professor, Department of Chemistry\r2013-2017Associate Dean (T&L), Faculty of Science\r2016-2016-present Interim Dean, Faculty of Science Associate Head, Department of Chemistry研究领域
""Organic chemistry"""Research Areas \rDevelopment of new organic synthetic methodology近期论文
Intramolecular (4+3) Cycloadditions of Pyrroles and Application to the Synthesis of Class II Galbulimima Alkaloids. He, J.; Chen, Z.; Li, W.; Low, K.H.; Chiu, P.* Angew. Chem. Int. Ed. 2018, 57, 5253-5256. doi: 10.1002/anie.201711439\r\rSynthesis and Applications of Unquaternized C-bound Boron Enolates. Ng., E. W. H.; Low, K.H.; Chiu, P.* J. Am. Chem. Soc. 2018, 140, 3537-3541. doi:10.1021/jacs.8b00614\r\rApplication of a Rhodium-catalyzed Cyclization Cycloaddition Cascade Strategy to the Total Synthesis of (-)-Curcumol. Zhang, X. X.;* Ko, R. Y. Y.; Xie, X. Q.; Qi, W. P.; Li, P. C.; Chiu, P.* Org. Chem. Front., 2018, 5, 1092-1095. doi: 10.1039/C7QO01150D\r\rTransannular [4+3] Cycloadditions of Macrocyclic Epoxy Ketones. Chan, D.; Chen, Y.; Low, K. H.; Chiu, P.* Chem.-Eur. J. 2018, 24, 2375-2378. doi: 10.1002/chem.201800019/full\r\rAbstract: Transannular [4+3] cycloadditions of dienophiles derived from macrocyclic epoxy ketones produce fused ring systems having central cycloheptane subunits. In some cases, base directly induced cycloisomerization of the epoxy ketones to yield the cycloadducts; in others, the epoxy ketones were transformed into their corresponding enolsilanes before undergoing cycloaddition. Enantiomerically-enriched tricyclic arrays are obtained from cycloadditions starting from optically pure epoxy ketones.\r\rAn Approach to the Welwistatin Core via a Diazoketone Rearrangement–Ring Expansion Strategy. Lam. S. M.; Wong, W. T.; Chiu, P.* Org. Lett. 2017, 19, 4468–4471. DOI: 10.1021/acs.orglett.7b01988\r\rRearrangements of α-Diazo-β-Hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones. Li, Z.; Lam, S. M.; Ip, I.; Wong, W. T.; Chiu, P.* Org. Lett. 2017, 19, 4464–4467. DOI: 10.1021/acs.orglett.7b01963\r\rA Natural Product-like JAK2/STAT3 Inhibitor Induces Apoptosis of Malignant Melanoma Cells. Wu, K. J.; Huang J. M.; Zhong, H. J.; Dong Z. Z.; Liu, C.; Lu, J.-J.; Chen, X. P.; Chiu, P; Kwong, D. W.; Han, Q. B.; Ma, D. L.*; Leung, C. H.* PLoS One, 2017, 12(6) e0177123. DOI: 10.1371/journal.pone.0177123\r\rDearomative Intramolecular (4+3) Cycloadditions of Arenes with Epoxy and Aziridinyl Enolsilanes. Ling, J.; Lam, S.; Low, K.-H.; Chiu, P.* Angew. Chem., Int. Ed. 2017, 56, 8879–8882. DOI: 10.1002/anie.201704155\r\rTetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms. Wong, V. K. W.; Zeng, W.; Chen J.; Yao, X. J.; Leung, E. L.; Wang Q. Q.; Chiu, P.*; Ko, B. C. B.*; Law, B. Y. K.* Front. Pharmacol. 2017, 8:351. DOI: 10.3389/fphar.2017.00351\r\r3-Quinuclidinol. First Update. Y. Chen, Chiu, P.* In: Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). John Wiley & Sons, 2016.\r\r\ 相关热点
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