个人简历

2000年7月毕业于汉中师范学院，获理学学士；2003年7月毕业于西北农林科技大学植物资源化学专业，获理学硕士；2010年12月毕业于西北农林科技大学农药学专业，获农学博士。2003年7月留校工作，2011年遴选为硕士生导师，2012年晋升为副教授，2014年遴选为博士生导师。2005年在兰州大学化学与化工学院进修学习，2008年和2009年先后两次前往美国新泽西州立大学（Rutgers, The State University of New Jersey）药学院访问学习。

研究领域

（1）天然产物源农药的合成及其构效关系； （2）具有重要生物活性的天然产物分离纯化与结构修饰； （3）不对称催化法合成手性药物

近期论文

1. Li-Fei Zhu, Zhe Hou, Kun Zhou, Zong-Bo Tong, Qian Kuang, Hui-Ling Geng*, Le Zhou *. Synthesis, bioactivity and structure-activity relationships of new 2-aryl-8-OR-3,4-dihydro isoquinolin-2-iums salts as potential antifungal agents, Bioorg. Med. Chem. Lett. 2016, 26 , 2413–2417 (IF = 2.486). 2. Huiling Geng*, Xinchi Yu, Ailin Lu, Haoqiang Cao, Bohang Zhou, Le Zhou* and Zhong Zhao*. Extraction, Chemical Composition, and Antifungal Activity of Essential Oil of Bitter Almond, Internatonal Journal of Molecular Sciences 2016, 17(9) , 1421-1434 (IF = 3.257). 3. Wenjia Dan†, Huiling Geng†, Jianwen Qiao, Rui Guo , Shaopeng Wei, Wenjun Wu and Jiwen Zhang*. Efficient Synthesis and Antibacterial Evaluation of (±)-Yanglingmycin and Its Analogues, Molecules 2016, 21 , 96-111 (IF = 2.465, 并列第一). 4. Dongdong Wang, Chunbo Lu, Feifei Sun, Mingxu Cui, Haibo Mu, Jinyou Duan*, Huiling Geng*. A tanshinone I derivative enhances the activities of antibiotics against Staphylococcus aureus in vitro and in vivo, Research in Microbiology 2016, 167 , 1-9（IF = 2.154）. 5. Pseudocyanides of sanguinarine and chelerythrine and their series of structural -ly simple analogues as new anticancer lead compounds: Cytotoxic activity, structure–activity relationship and apoptosis induction. European Journal of Pharmaceutical Sciences 2015, 67 , 45–54 (IF = 3.773). 6. Zhao-Feng Gao, Bo-Hang Zhou, Jie-Yu Zhao, Fang-Jun Cao, Le Zhou*, Hui-Ling Geng*. Further Study on Chemical Constituents of Parnassia wightiana Wall: Four New Dihydro- β - agarofuran Sesquiterpene Polyesters, International Journal of Molecular Sciences 2015, 16 , 9119-9133 (IF = 3.257). 7. Rui Yang, Qiao Ruan, Bing-yu Zhang, Zuo-lue Zheng, Fang Miao, Le Zhou*, Hui-ling Geng*. A class of promising acaricidal tetrahydroisoquinoline derivatives: synthesis, biological evaluation and structure-activity relationships. Molecules 2014, 19 , 8051-8066 (IF = 2.465). 8. Goudu Liu, Zhao Li, Huiling Geng*, Xumu Zhang*. Rhodium-catalyzed regioselective hydroaminomethylation of terminal olefins by pyrrole-based tetraphosphrous ligands. Catalysis Science and technology 2014, 4 , 917-921 (IF = 5.287). 9. Huiling Geng, Xiaowei Zhang, Mingxin Chang, Le Zhou, Wenjun Wu*, Xumu Zhang*. Enantioselective synthesis of optically pure β -amino ketones and γ -aryl amines by Rh-catalyzed asymmetric hydrogenation. Advanced Synthesis and Catalysis 2011, 353 , 3039-3043 (IF = 6.453). 10. Huiling Geng, Kexuan Huang, Tian Sun, Wei Li, Xiaowei Zhang, Le Zhou, Wenjun Wu*, Xumu Zhang*. Ruthenium-catalyzed asymmetric hydrogenation of β -keto enamines: an efficient approach to chiral γ -amino alcohols. The Journal of Organic Chemistry 2011, 76 , 332-334 (IF = 4.785). 11. Huiling Geng, Weicheng Zhang, Jian Chen, Guhua Hou, Le Zhou, Yaping Zou, Wenjun Wu*, Xumu Zhang*.Rhodium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of β-Ketoenamide: Efficient Access to 1,3-Amino Alchols, Angew. Chem. Int. Ed. 2009, 48 , 6052–6054 (IF = 11.079). 12. Yaping Zou, Huiling Geng, Weicheng Zhang, Shichao Yu, Xumu Zhang*. Axially Chiral Electron-rich TunePhos-tye Ligand: Synthsis and Applications in Asymmetric Hydrogenation. Tetra. Lett.2009, 50 , 5777-5779 (IF = 2.347). 13. Jian Chen, Weicheng Zhang, Huiling Geng, Wei Li, Guohua Hou, Aiwen Lei, Xumu Zhang. Efficient Synthesis of Chiral β-Arylisopropylamines by Using Catalytic Asymmetric Hydrogenation, Angew. Chem. Int. Ed. 2009, 48, 800–802 (IF = 11.079). 14. Kexuan Huang, Xiaowei Zhang, Huiling Geng, Sheng-kun Li, Xumu Zhang*. Highly Enantioselective Hydrogenation of β-Ketoenamides with the Rh-ZhangPhos Catalyst. ACS Catal. 2012, 2 , 1343–1345 (IF = 9.307). 15. Tang-Lin Liu, Wei Li, Huiling Geng, Chun-Jiang Wang, Xumu Zhang. Catalytic Enantioselective Desymmetrization of Meso Cyclic Anhydrides via Iridium-Catalyzed Hydrogenation, Org. Lett. 2013, 15 , 1740-1743 (IF = 6.732). 16. Caiyou Chen, Yu Qiao, Huiling Geng, Xumu Zhang*. A Novel Triphosphoramidite Ligand for Highly Regioselective Linear Hydroformylation of Terminal and Internal Olefins. Org. Lett . 2013, 15 , 1048-1051 (IF = 6.732). 17. Ming Zhou, Dong, Dejun Dong, Zhu, Baolin Zhu, Huiling Geng, Wang, Yan Wang, Xumu Zhang. Rhodium-Catalyzed Enantioselective Hydrogenation of beta-Acylamino Nitroolefins: A New Approach to Chiral beta-Amino Nitroalkanes, Org. Lett. 2013, 15 , 5524-5527 (IF = 6.732).