个人简历

正辉教授，博士生导师。2004年获得兰州大学学士学位；2009年获得兰州大学和美国Rutgers University 联合培养理学博士学位（首届国家建设高水平大学公派研究生，导师：梁永民教授和张绪穆教授），2011年全国优秀博士学位论文提名奖获得者。\r
2009年任职于西北大学，2011年被破格遴选为博士生导师，2014年特评教授。现已在JACS、Angew. Chem.、Sci. Bull.、Sci. China Chem.、ACS Catal.等国际著名期刊发表论文80余篇，他引2000余次，授权国家发明专利4项。主持国家自然科学基金多项。\r
2011年获得西北大学优秀教师称号，2012年获得陕西省青年科技新星称号，2013年获得陕西省自然科学优秀学术论文一等奖，2014年获得陕西化学优秀青年奖，2014年获得陕西省研究生创新成果展特等奖指导教师，2015年获得中国化学会青年化学奖，2015年获得Membership Award in the American Chemical Society，2016年获得国家优秀青年科学基金资助，2016年获得Thieme Chemistry Journal Award，2017年获得西北大学优秀研究生学位论文指导教师，2018年获得陕西省优秀博士学位论文奖指导教师。现任《化学学报》和《Frontiers in Chemistry》期刊编委。主要研究方向为有机合成化学，不对称催化和有机功能材料化学

研究领域

"""""有机合成，不对称催化，羰基化反应，有机功能材料"

近期论文

Ming Chen, Xucai Wang, Pengfei Yang, Xun Kou, Zhi-Hui Ren, Zheng-Hui Guan*, Palladium-Catalyzed Enantioselective Heck Carbonylation with a Monodentate Phosphoramidite Ligand: Asymmetric Synthesis of (+)-Physostigmine, (+)-Physovenine, and (+)-Folicanthine. Angew. Chem. Int. Ed., 2020, 59,12199-12205. DOI:10.1002/anie.202003288.\r
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Mi-Na Zhao, Ying Zhang, Ning Ge, Le Yu, Shun Wang, Zhi-Hui Ren, Zheng-Hui Guan*, A Rh(III)-Catalyzed Regioselective Intermolecular oxa-Pauson-Khand Reaction of Alkynes, Arylboronic Acids and CO to form Butenolides. Org. Chem. Front., 2020, 7, 763-767. \r
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Xun Kou, Qingyang Zhao, Zheng-Hui Guan*, Copper-Catalyzed Asymmetric Dearomative Alkynylation of Isoquinolines. Org. Chem. Front., 2020, 7, 829-833.\r
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Xucai Wang, Ming Chen, Wei Zhang, Yao-Du Zhang, Zhi-Hui Ren, Zheng-Hui Guan*, Palladium-Catalyzed 5-Exo-trig Hydroamidation of β,γ-Unsaturated Hydrazones for Synthesis of Dihydropyrazoles. Chin. J. Org. Chem.(中国有机化学), 2020, 40, DOI: 10.6023/cjoc202002009\r
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2019年：\r
Mi-Na Zhao, Zheng-Hui Guan*, Synthesis of 2,3-Diaryl-2H-azirines via Cs2CO3-Mediated Cyclization of Ketoxime Acetates. Org. Synth., 2019, 96, 66-79\r
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2018年：\r
Ming Chen, Mi-Na Zhao, Yao-Du Zhang, Zhi-Hui Ren, Zheng-Hui Guan*, Palladium-Catalyzed Oxidative Cyclopropanation of Enamides and Norbornenes Initiated by C-H Activation. Science China: Chem, 2018, 61: 695-701 (Cover Page).\r
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Yong-Qiang Guo, Mi-Na Zhao, Zhi-Hui Ren, Zheng-Hui Guan*, Copper-Promoted 6-endo-trig Cyclization of β,γ-Unsaturated Hydrazones for the Synthesis of 1,6-Dihydropyridazines. Org. Lett., 2018, 20, 3337-3340.\r
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Mi-Na Zhao, Zhi-Jing Zhang, Zhi-Hui Ren, De-Suo Yang, Zheng-Hui Guan*, Copper-Catalyzed Oxidative Cyclization/1,2-Amino Migration Cascade Reaction. Org. Lett., 2018, 20, 3088-3091.\r
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Mi-Na Zhao, Zhi-Hui Ren, De-Suo Yang, Zheng-Hui Guan*, Iron-Catalyzed Radical Cycloaddition of 2H-Azirines and Enamides for the Synthesis of Pyrroles. Org. Lett., 2018, 20, 1287-1290.\r
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Mi-Na Zhao, Wei Zhang, Xu-Cai Wang Ying Zhang, De-Suo Yang, Zheng-Hui Guan*, Modular 2,3-diaryl-2H-azirine synthesis from ketoxime acetates via Cs2CO3-mediated cyclization. Org. Biomol. Chem., 2018, 16, 4333-4337.\r
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Wei Zhang, Mi-Na Zhao, Ming Chen, Zhi-Hui Ren, Zheng-Hui Guan*, Palladium-Catalyzed Regioselective Cyclocarbonylation of N-(3-Phenylprop-2-ynyl)anilines with Carbon Monoxide and Alcohols for the Synthesis of Quinoline-3-carboxylic Esters. Asian J. Org. Chem., 2018, 7, 1605-1608.\r
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2017年：\r
Yukun Yi, Mi-Na Zhao, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Synthesis of Symmetrical Pyridines by Iron-Catalyzed Cyclization of Ketoxime Acetates and Aldehydes. Green Chem., 2017, 19, 1023-1027.\r
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Muhammad Usman, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Copper-Catalyzed Reaction of Oximes with Diisopropyl Azodicarboxylate: An Alternative Method for the Synthesis of Oxime Carbonates. Org. Biomol. Chem., 2017, 15, 1091-1095.\r
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Muhammad Usman, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Recent Developments in Cobalt Catalyzed C-C and C-Heteroatom Bond Formation via C-H Bond Functionalization. Synthesis, 2017, 49, 1419-1443. (Invited Reviews). \r
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Mi-Na Zhao, Le Yu, Nan-Fang Mo, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Synthesis of Tetrasubstituted Symmetrical Pyridines by Iron-Catalyzed Cyclization of Ketoxime Acetates. Org. Chem. Front., 2017, 4, 597-602. \r
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Shun Wang, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, K2CO3-Mediated Cyclization and Rearrangement of γ,δ-Alkynyl Oximes to Form Pyridols. Org. Lett. 2017, 19, 1574-1577.\r
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Mi-Na Zhao, Mei-Na Zhang, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Base-Mediated Formal [3+2] Cycloaddition of β,γ-Alkenyl Esters and p-TsN3 for the Synthesis of Pyrazoles;. Science Bull. 2017, 62,493-496.\r
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Ming Chen, Wei Zhang, Zhi-Hui Ren,Yao-Yu Wang, Zheng-Hui Guan*, PhI(OAc)2-Promoted Umpolung Acetoxylation of Enamides for the Synthesis of α-Acetoxy Ketones. Science China: Chem., 2017, 60, 761-768.\r
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Ming Chen, Le Yu, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Palladium-Catalyzed Oxidative Carbonylation of N-Aryl Enamino Esters with CO and Alcohols: Synthesis of N-Aryl Aminomethylenemalonates. Chem. Commun., 2017, 53, 6243-6246. \r
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Peng Gao, Juan Wang, Zijing Bai, Desuo Yang, Ming-Jin Fan, Zheng-Hui Guan*, Synthesis of Substituted 2-Amino-1,3-Oxazoles via Copper-Catalyzed Oxidative Cyclization of Enamines and N,N-Dialkyl Formamides. Chem. Asian J., 2017, 12, 1865-1868.\r
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2016年：\r
Mi-Na Zhao, Le Yu, Rong-Rong Hui, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Iron-Catalyzed Dehydrogenative [4 + 2] Cycloaddition of Tertiary Anilines and Enamides for the Synthesis of Tetrahydroquinolines with Amido-Substituted Quaternary Carbon Centers. ACS Catal., 2016, 6, 3473-3477.\r
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Mi-Na Zhao, Zhi-Hui Ren, Le Yu, Yao-Yu Wang, Zheng-Hui Guan*, Iron-Catalyzed Cyclization of Ketoxime Carboxylates and Tertiary Anilines for the Synthesis of Pyridines. Org. Lett., 2016, 18, 1194-1197.\r
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Mei-Na Zhang, Mi-Na Zhao, Ming Chen, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Copper-Catalyzed Radical Coupling of 1,3-Dicarbonyl Compounds with Terminal Alkenes for the Synthesis of Tetracarbonyl Compounds. Chem. Commun., 2016, 52, 6127-6130.\r
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Peng Gao, Juan Wang, Zi-Jing Bai, Li Shen, Yun-Yun Yan, De-Suo Yang, Ming-Jin Fan, Zheng-Hui Guan*, Synthesis of Polycarbonyl Pyrroles via K2S2O8-Mediated Oxidative Cyclization of Enamines. Org. Lett., 2016, 18, 6074-6077. \r
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Shun-Jiang Yao, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Friedel-Crafts Fluoroacetylation of Indoles with Fluorinated Acetic Acids for the Synthesis of Fluoromethyl Indol-3-yl Ketones under Catalyst- and Additive-Free Conditions. J. Org. Chem., 2016, 81, 4226-4234. \r
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Shun-Jiang Yao, Zhi-Hui Ren, Zheng-Hui Guan*, Recent Advances on the Synthesis of Acylindoles. Tetrahedron Letters, 2016, 57, 3892-3901 (Invited Reviews). \r
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Bo Liu, Hui-Fang Zhou, Zheng-Hui Guan, Lei Hou, Bin Cui, Yao-Yu Wang, Cleavage of a C-C σ Bond between two Phenyl Groups under mild Conditions During the Construction of Zn(II) Organic Frameworks. Green Chem., 2016, 18, 5418-5422. \r
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Ni-Ni Zhou, Hai-Tao Zhu, De-Suo Yang, Zheng-Hui Guan*, Recent Developments in the Group-1B-Metal-Catalyzed Synthesis of Pyrroles. Org. Biomol. Chem., 2016, 14, 7136-7149. 影响因子：3.49 SCI三区，JCR:Q1\r
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Zhi-Hui Ren*, Mi-Na Zhao, Yukun Yi, Yao-Yu Wang, Zheng-Hui Guan*, Copper-Catalyzed Aerobic Oxidative Cyclization of Ketoxime Acetates with Pyridines for the Synthesis of Imidazo[1,2-a]pyridines. Synthesis. 2016, 48, 1920-1926 (Invited Special Topic). \r
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Zhi-Hui Ren,* Mi-Na Zhao, Zheng-Hui Guan*, CuI-Catalyzed Oxidative Cross Coupling of Oximes with Tetrahydrofuran: a Direct Access to o-tetrahydrofuran-2-yl oxime Ethers. RSC Adv. 2016, 6, 16516-16519.\r
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Muhammad Usman, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Copper-Catalyzed Carbonylation of Anilines by Diisopropyl Azodicarboxylate for the Synthesis of Carbamates. RSC Adv., 2016, 6, 107542-107546. \r
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2015年：\r
Mi-Na Zhao, Longfei Ran, Ming Chen, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Palladium-Catalyzed Carbonylation of Indoles for Synthesis of Indol-3-yl Aryl Ketones. ACS Catal., 2015, 5, 1210-1213. \r
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易育堃，陈明，关正辉*，碳氢键活化一氧化碳羰基化偶联反应研究进展。科学通报, 2015, 60, 2927-2941.\r
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Ming Chen, Zhi-Hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, Palladium-Catalyzed Oxidative Carbonylation of Aromatic C-H Bonds of N-Alkylanilines with CO and Alcohols for the Synthesis of o-Aminobenzoates. J. Org. Chem., 2015, 80, 1258-1263. \r
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Hai-Tao Zhu,* Ming-Jin Fan, De-Suo Yang,* Xiao-Ling Wang, Sen Ke, Chao-Yang Zhang, Zheng-Hui Guan*, An Iodine-Promoted Meyer-Schuster Rearrangement for the Synthesis of α-Iodo Unsaturated Ketones. Org. Chem. Front., 2015, 2, 506-509.\r
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Hao Liang, Zhi-hui Ren, Yao-Yu Wang, Zheng-Hui Guan*, One-Pot Green Synthesis of Enamides and 1,3-Diynes. Chin. J. Catal.（催化学报）, 2015, 36, 113-118. \r
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De-Suo Yang,* Sen Ke, Ming-Jin Fan, Hai-Tao Zhu, Xiao-Ling Wang, Zheng-Hui Guan*, A Facile and Efficient Synthesis of Six-Membered Enol Carbocyclic Compounds. Synlett, 2015, 26, 2826-2830.