个人简历

生命科学与技术学院大型仪器实验共享平台副主任\r
2000年，西北大学生物系获硕士学位\r
2004年，西安交通大学生物医学工程系获博士学位\r
2006-2008年，美国威斯康星医学院生理系博士后\r
2008年入选教育部“新世纪优秀人才”支持计划\r
2009年，美国威斯康星医学院生理系访问学者

研究领域

"""""盐敏感高血压的差异蛋白质组学与代谢组学\r
盐敏感高血压的药物靶标筛选以及诊断试剂盒开发\r
生物质谱分析技术及食品安全检测\r
盐敏感高血压的生物信息学分析"

近期论文

Zhe Yang*, Rui Cheng, Chenyang Zhao, Na Sun, Huiyan Luo, Ya Chen, Zerong Liu, Xian Li, Jie Liu, Zhongmin Tian* Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors. Theranostics， 2018; 8(15): 4097-4115.SCI 一区 IF：8.8\r
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Na Sun, Chenyang Zhao, Rui Cheng, Zerong Liu, Xian Li, Axin Lu, Zhongmin Tian*and Zhe Yang. Cargo-Free Nanomedicine with pH Sensitivity for Codelivery of DOX Conjugated Prodrug with SN38 To Synergistically Eradicate Breast Cancer Stem Cells. Mol. Pharmaceutics, DOI: 10.1021/acs.molpharmaceut.8b00367 SCI 二区\r
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Yuan Cheng, Haiying Song,Xiaoqing Pan, Hong Xue, Yifei Wan, Tao Wang, Zhongmin Tian, Entai Hou, Ian R. Lanza, Pengyuan Liu, Yong Liu, Purushottam W. Laud, Kristie Usa, Yongcheng He, Mingyu Liang Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet. Theranostics. 2018; 8(6): 1468-1480 SCI 一区 IF: 8.766\r
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Entai Hou, Na Sun, Fuchang Zhang, Chenyang Zhao, Kristie Usa, Mingyu Liang*, Zhongmin Tian,* Malate and Aspartate Increase L-arginine and Nitric Oxide and Attenuate Salt-Sensitive Hypertension. Cell Reports. 2017 19, 1631–1639 IF: 8.28\r
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Yang Z, Sun N, Cheng R, Zhao C, Liu Z, Li X, Liu J, Tian Z. pH multistage responsive micellar system with charge-switch and PEG layer detachment for co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells. Biomaterials. 2017 Sep 10;147:53-67. doi: 10.1016/j.biomaterials.. SCI 一区IF:8.402\r
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Yang Z., Sun N., Cheng R., Zhao C. Y., Liu J. and Tian Z. Hybrid nanoparticles coated with hyaluronic acid lipoid for targeted co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells (2017). Journal of Materials Chemistry B, 5: 6762-6775. IF:4.543 SCI 一区\r
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Zhongmin Tian, Yong Liu, Kristie Usa, Domagoj Mladinov, Yi Fang, Xiaoqiang Ding, Andrew S. Greene, Allen W. Cowley, Jr. Mingyu Liang*. Novel Role of Fumarate Metabolism in Dahl-Salt Sensitive Hypertension. Hypertension. 2009, 54: 255-260. IF: 7.194\r
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Zhongmin Tian, Andrew S. Greene, Jennifer Pietrusz, Isaac R. Matus, and Mingyu Liang MicroRNA–target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis Genome Research. 2008.18:404-411. IF: 11.224\r
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Zhongmin Tian, Andrew S. Greene, Kristie Usa, Isaac R. Matus, Jesse Bauwens, Jennifer L. Pietrusz, Allen W. Cowley, Jr. and Mingyu Liang. Renal Regional Proteomes in Young Dahl Salt-Sensitive Rats. Hypertension. 2008,51(4):899-904. IF: 7.194\r
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Alison J. Kriegel, Yi Fang, Yong Liu, Zhongmin Tian，Domagoj Mladinov，Isaac R. Matus, Xiaoqiang Ding, Andrew S. Greene and Mingyu Liang. MicroRNA-Target Pairs in Human Renal Epithelial Cells treated with Transforming Growth Factor β1: A Novel Role of miR-382 Nucleic Acids Research. 2010, 38(22): 8338-8347. IF：7.479\r
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Xiaofeng He, Yong Liu, Kristie Usa , Zhongmin Tian, Allen W. Cowley Jr., Mingyu Liang. Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats. Am J Physiol Renal Physiol. 2014, 15; 306(10):1190-1197. IF：3.3\r
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Mingyu Liang, Yong Liu, Domagoj Mladinov, Allen W. Cowley, Jr., Hariprasad Trivedi, Yi Fang, Xialian Xu, Xiaoqiang Ding, Zhongmin Tian. MicroRNA: A New Frontier in Kidney and Blood Pressure Research. Am J Physiol Renal Physiol, 2009，297:553-558. IF：4.416\r
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Usa K, Liu Y, Geurts AM, Cheng Y, Lazar J, Baker MA, Grzybowski M, He Y, Tian Z*, Liang M*. Elevation of fumarase attenuates hypertension and can result from a nonsynonymous sequence variation or increased expression depending on rat strain. Physiol Genomics. 2017 Sep 1;49(9):496-504. IF:3.04 \r
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Hou E, Li X, Liu Z, Zhang F, Tian Z. Combined metabolomic and correlation networks analyses reveal fumarase insufficiency altered amino acid metabolism. Biomed Chromatogr. 2017 Nov 11. doi: 10.1002/bmc.4133.\r
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Liqing He, Xiaochang Xue, Zhengjun Wang, Entai Hou, Yong Liu, Mingyu Liang, Yingqi Zhang, and Zhongmin Tian* Transcriptional regulation of heterogeneous nuclear ribonucleoprotein K gene expression, Biochimie, 2015, 109, 27-35 IF: 3.2\r
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Le Wang , Entai Hou, Lijun Wang, Yanjun Wang, Lingjian Yang, Xiaohui Zheng, Guangqi Xie, Qiong Sun, Mingyu Liang, Zhongmin Tian* Reconstruction and analysis of correlation networks based on GC–MS metabolomics data for young hypertensive men, Analytica Chimica Acta , 2015,854: 95–105 IF：4.517\r
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Le Wang, Entai Hou, Liqing He, Zhengjun Wang, Na Sun, Lan Chen, Pu Jia, Xiaohui Zheng, Mingyu Liang, Zhongmin Tian* Analysis of metabolites in plasma reveals distinct metabolic features between Dahl salt-sensitive rats and consomic SS.13BN rats. Biochemical and Biophysical Research Communications, 2014, 18, 450 (1): 863-869. IF: 2.4\r
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Zhengjun Wang, Qiong Sun, Na Sun, Mingyu Liang, Zhongmin Tian* Mitochondrial dysfunction and altered renal metabolism in Dahl salt-sensitive rats. Kidney Blood Press Res. 2017, 42(3):587-597. IF:2.9