个人简历
Employment\rJul/2015 –\tProfessor (教授)\rOrganic Chemistry Research Center (OCRC)\rFrontier Institute of Science and Technology (FIST),\rXi’an Jiaotong University (XJTU), Xi’an, China\r \rMay/2014 –Jun/2015 \tLab Director II (实验室主任II类)\rOrganic Chemistry Research Center (OCRC)\rFrontier Institute of Science and Technology (FIST),\rXi’an Jiaotong University (XJTU), Xi’an, China\r \rNov/2011 – Apr/2014\tPrincipal Investigator at the level of Professor,\rGroup Leader I (研究小组主任I类)\rOrganic Chemistry Research Center (OCRC)\rFrontier Institute of Science and Technology (FIST),\rXi’an Jiaotong University (XJTU), Xi’an, China\r \rMar/2010 – Oct/2011\tPostdoctoral Associate (Advisor: Prof. Stephen L. Buchwald)\rDepartment of Chemistry\rMassachusetts Institute of Technology, Cambridge, MA, USA\r \rApr/2005 – Sep/2006\tResearch chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China\r \rJul/2004 – Mar/2005\tResearch chemist, Chinese Wisdom Institute of Medicine and Wisdom Pharmaceutica Co. Ltd, Haimen, China\r \rEducation\rOct/2006 – Feb/2010\tPh.D. in Organic Chemistry (Advisor: Prof. Dirk Menche)\rDissertation: Total synthesis of etnangien and studies towards the\rtotal synthesis of rhizopodin\rHeidelberg University, Heidelberg, and Helmholtz Center for Infection Research (HZI), Braunschweig, Germany\r\rSep/2001 – Jun/2004\tM.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li)\rDissertation: Synthesis and biological activities of novel\rsulfonylurea compounds\rNankai University, Tianjin, China\r\rSep/1997 – Jul/2001\tB.S. in Chemistry, Shanxi Normal University, Linfen, China\r \rHonors and Awards\r2015\tThieme Chemistry Journal Award, Germany\r2015\t“陕西省青年科技新星”, Shaanxi Province\r2010\tThe highest honor (summa cum laude) for the Ph.D. dissertation in\rHeidelberg University, Germany
研究领域
"""""Homogeneous Catalysis • Medicinal Chemistry • Natural Products• Flow Chemistry\r1. Development of novel catalytic reactions for efficient construction of functionalized\rcomplex molecules that may be used as chemical probes in chemical biology or as organic\rmaterials\r2. Total synthesis of bioactive natural products and their analogs for drug discovery and\rdevelopment\r3. Continuous microflow synthesis for more user-friendly and more sustainable
近期论文
Guanghui Wang, Liang Xu and Pengfei Li,* Double N,B-type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation, J. Am. Chem. Soc. 2015, 137, 8058-8061.\r\rLiang Xu, Shuai Zhang, Pengfei Li,* Boron-selective reactions as powerful tools for modular synthesis of diverse complex molecules, Chem. Soc. Rev. 2015, 44, DOI:10.1039/c5cs00338.\r\rLiang Xu, Siyi Ding, Pengfei Li,* Site-differentiated Polyboron Arenes Prepared by Direct C-H Borylation and Their Highly Selective Suzuki-Miyaura Cross-Coupling Reactions, Angew. Chem. Int. Ed. 2014, 53, 1822-1826.\r\rGuanghu Tong, Zhi Liu, Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach, Org. Lett. 2014, 16, 2288-2291.\r\rXiaowu Liu, Fei Xiong, Xuanping Huang, Liang Xu, Pengfei Li,* and Xiaoxing Wu,* Copper-Catalyzed Trifluoromethylation-Triggered Neophyl-Type Rearrangement of α,α-Diaryl Allylic Alcohols, Angew. Chem. Int. Ed. 2013, 52, 6962-6966.\r\rPengfei Li,* Jason S. Moore, Klavs F. Jensen,* A Microfluidic System for the Continuous Recycling of Unmodified Homogeneous Palladium Catalysts via Liquid-Liquid Phase Separation, ChemCatChem 2013, 5, 1729-1733.\r\rPengfei Li, Stephen L. Buchwald,* Continuous-Flow Synthesis of 3,3-Disubstituted Oxindoles by a Palladium-Catalyzed -Arylation/Alkylation Sequence, Angew. Chem. Int. Ed. 2011, 50, 6396-6400.\r\rPengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Stereoselective Total Synthesis of Etnangien and Etnangien Methyl Ester, J. Org. Chem. 2010, 75, 2429-2444.\r\rPengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Total Synthesi of Etnangien, J. Am. Chem. Soc. 2009, 131, 11678-11679.\r\rPengfei Li, Dirk Menche*, Cycloadditions in the Total Synthesis of Sporolide B, Angew. Chem. Int. Ed. 2009, 48, 5078-5080.
