个人简历

学习经历：
1997.9－2002.7 中国药科大学，中药药理学，本科
2002.9－2007.6 中国药科大学，药物分析学，博士
工作经历：
2007.8－至今 苏州大学药学院，药物分析系，讲师、副教授、教授
2008.9－2011.8 苏州大学医学生物技术研究所，博士后
2013.6－2014.6 美国加州大学戴维斯分校，博士后

研究领域

（1）抗肿瘤新药研发
（2）药物代谢动力学
（3）肿瘤药物基因组学

近期论文

（1）Chen Q#, Mao Y#, Meng FY, Wang L, Zhang HJ, Wang WP*, Hua D*. Rs7911488 modified the efficacy of capecitabine-based therapy in colon cancer through altering miR-1307-3p and TYMS expression. Oncotarget, 2017, 8(43):94312-9. （IF2017: 5.168; 一区）
（2）Chen Q#, Meng FY#, Wang L, Mao Y, Zhou H, Hua D, Zhang HJ, Wang WP*. A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients. Scientific Reports, 2017 Aug 1;7(1):7059. （IF2017: 4.259; 二区）
（3）Tao LH#, Zhou XR#, Li FC, Chen Q, Meng FY, Mao Y, Li R, Hua D, Zhang HJ, Wang WP*, Chen WC*. A polymorphism in the promoter region of PD-L1 serves as a binding-site for SP1 and is associated with PD-L1 overexpression and increased occurrence of gastric cancer. Cancer Immunol Immunother, 2017 Mar;66(3):309-318. （IF2017: 4.711; 二区）
（4）Zhou XR#, Mao Y#, Zhu JJ, Meng FY, Chen Q, Tao LH, Li R, Fu FQ, Liu CP, Hu YJ, Wang WP*, Zhang HJ, Hua D, Chen WC, Zhang XG. TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis. Oncotarget. 2016 Oct 11;7(41):67196-67211. （IF2016: 5.008; 一区）
（5）Tang R#, Qi Q#, Wu R, Zhou X, Wu D, Zhou H, Mao Y, Li R, Liu C, Wang L, Chen W, Hua D, Zhang H, Wang WP*. The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment. Carcinogenesis, 2015 Aug;36(8):867-75. （IF2015: 5.334; 二区）
（6）Wang WP#, Ho PY#, Chen QX#, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, Li T, Wun T, White RD, Lam KS, Yu AM*. Bioengineering novel chimeric microRNA-34a for prodrug cancer therapy: High-yield expression and purification, and structural and functional characterization. J Pharmacol Exp Ther. 2015 Aug;354(2):131-41. （IF2015: 3.972; 二区）
（7）Wang WP, Li F, Mao Y, Zhou H, Sun J, Li R, Liu CP, Chen WC, Hua D*, Zhang XG*. A miR-570 binding-site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma. Hum Genet. 2013 Jun;132(6):641-8. （IF2013: 4.633; 二区）
（8）Wang WP#, Sun J#, Li F, Li R, Gu YP, Liu CP, Yang P, Zhu M, Chen LJ, Tian WY, Zhou H, Mao Y, Zhang L, Jiang JT, Wu CP, Hua D, Chen WC, Lu BF, Ju JF*, Zhang XG*. A frequent somatic mutation in CD274 3’-UTR leads to protein over-expression in gastric cancer by disrupting miR-570 binding. Hum Mutat, 2012 Mar;33(3):480-4.（IF2012: 5.686; 二区）
（9）Ren L, Gao YZ, Yin JH, Shi WX, Yu XW, Xie HP*, Wang WP*. The determination for the three genotypes of D16S539 locus based on near-infrared spectroscopy and chemical pattern recognition. Anal Chim Acta. 2009 Apr 13;638(2):202-8. (IF2009: 3.757; 二区)
（10）Wang WP, Sun WM, Wu WJ, Zhou GH. Improved adapter-ligation mediated allele-specific amplification for multiplex genotyping by using software. Electrophoresis. 2008 Apr;29(7):1490-501. (IF2008: 3.509; 二区)