个人简历
教育经历： 1. 2004/9–2012/6， 厦门大学， 生物化学与分子生物学， 博士 2. 2000/9–2004/6， 厦门大学， 生物学， 学士 科研与学术工作经历： 2016/8-至今，厦门大学，公共卫生学院，副教授 2012/7-2016/7，厦门大学，公共卫生学院，助理教授 2008-至今，厦门大学NIDVD，病毒-宿主相互作用研究组组长
研究领域
病毒、疫苗诱导的宿主B细胞（抗体）免疫应答研究（戊型肝炎病毒、乙型肝炎病毒、流感病毒、呼吸道合胞病毒） 病毒受体、感染机制及免疫逃逸机制研究（戊型肝炎病毒、呼吸道合胞病毒） 戊型肝炎临床新特征及肝外感染症状研究 呼吸道合胞病毒（致儿童肺炎）预防及治疗性疫苗、药物研发 肿瘤组织浸润性B细胞研究
近期论文
Chang Liu, Wei Cai, Xin Yin, Zimin Tang, Guiping Wen, Charuta Ambardekar, Xinlei Li, Dong Ying, Zongdi Feng*, Zizheng Zheng*, Ningshao Xia, An Optimized High-Throughput Neutralization Assay for Hepatitis E Virus (HEV) Involving Detection of Secreted Porf2, Viruses, 2019, 11(1) (Co-Corresponding author) Xue Liu#, Chao Liu#, Zizheng Zheng#, Siyuan Chen, Xin Pang, Xinchu Xiang, Jixian Tang, En Ren, Yuanzhi Chen, Min You, Xiaoyong Wang, Xiaoyuan Chen, Wenxin Luo,* Gang Liu,* and Ningshao Xia*. Vesicular Antibodies: A Bioactive Multifunctional Combination Platform for Targeted Therapeutic Delivery and Cancer Immunotherapy. Advanced Materials, 2019, (Accepted, Co-First author) Si-Ling Wang, Birendra Prasad Gupta, Wen-Fang Ji, Zi-Min Tang, Gui-Ping Wen, Anurag Adhikari, Dong Ying, Xu Zhang, Chang Liu, Zi-Zheng Zheng*, Ning-Shao Xia. Application of Hepatitis E Virus-Related Markers on Samples from a Developing Country. Clin. Lab. 2019;65:235-241 (Corresponding author) Xin Yin, Dong Ying, Sébastien Lhomme, Zimin Tang, Christopher M. Walker, Ningshao Xia, Zizheng Zheng*, Zongdi Feng*, Origin, antigenicity, and function of a secreted form of ORF2 in hepatitis E virus infection, Proceedings of the National Academy of Sciences of USA, 2018, 115(18): 4773-4778 (Co-Corresponding author) Guiping Wen, Changrong Chen, Xiuyu Song, Zimin Tang, Wenfang Ji, Siling Wang, Ke Zhang, Jun Zhang, Shanhai Ou*, Zizheng Zheng*, Ningshao Xia, Long-term HEV carriers without antibody seroconversion among eligible immunocompetent blood donors, Emerging Microbes & Infecttions, 2018, 7(1): 125 (Co-Corresponding author) Min Zhao#, Zi-Zheng Zheng#, Man Chen, Kayvon Modjarrad, Wei Zhang, Lu-Ting Zhan, Jian-Li Cao, Yong-Peng Sun, Jason S. McLellan, Barney S. Graham*, Ning-Shao Xia*, Discovery of prefusion respiratory syncytial virus F-specific monoclonal antibody that provides greater in vivo protection than the murine precursor of Palivizumab, Journal of Virology, 2017, 91(15): 1-17 (Co-First author) Tian, Daiyin#; Battles, Michael B.#; Moin, Syed M.; Chen, Man; Modjarrad, Kayvon; Kumar, Azad; Kanekiyo, Masaru; Graepel, Kevin W.; Taher, Noor M.; Hotard, Anne L.; Moore, Martin L.; Zhao, Min; Zheng, Zi-Zheng; Xia, Ning-Shao*; McLellan, Jason S.*; Graham, Barney S*. Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibodytargeting the fusion glycoprotein, Nature Communications, 2017.11.30, 8: 1~7 Wen, Gui-Ping#; Tang, Zi-Min#; Wang, Si-Ling; Ji, Wen-Fang; Cai, Wei; Zhang, Xu; Huang, Shou-Jie; Wu, Ting; Zhang, Jun; Zheng, Zi-Zheng*; Xia, Ning-Shao*, Classification of human and zoonotic group hepatitis E virus (HEV) using antigen detection, Applied Microbiology and Biotechnology, 2017.12, 101(23-24): 8585~8594(Co-Corresponding author) Cai, Wei#; Tang, Zi-Min#; Wen, Gui-Ping; Wang, Si-Ling; Ji, Wen-Fang; Yang, Min; Ying, Dong; Zheng, Zi-Zheng*; Xia, Ning-Shao*. A high-throughput neutralizing assay for antibodies and sera against hepatitis E virus, Scientific Reports, 2016.4.28, 6: 1~8(Co-Corresponding author) Tang, Zi-Min; Wang, Si-Ling; Ying, Dong; Wen, Gui-Ping; Cai, Wei; Zhang, Ke; Ji, Wen-Fang; Yang, Ming; Zheng, Zi-Zheng*; Xia, Ning-Shao*. The Bama miniature swine is susceptible to experimental HEV infection, Scientific Reports, 2016.8.18, 6: 1~6(Co-Corresponding author) Wen, Gui-Ping#; Tang, Zi-Min#; Yang, Fan; Zhang, Ke; Ji, Wen-Fang; Cai, Wei; Huang, Shou-Jie; Wu, Ting; Zhang, Jun; Zheng, Zi-Zheng*; Xia, Ning-Shao*. A valuable antigen detection method for diagnosis of acute hepatitis e. Journal of Clinical Microbiology, 2015.3.01, 53(3): 782~788(Co-Corresponding author) Min Zhao#, Xiao-Jing Li#, Zi-Min Tang, Fan Yang, Si-Ling Wang, Wei Cai, Ke Zhang, Ning-Shao Xia*, Zi-Zheng Zheng*, A comprehensive study of neutralizing antigenic sites on the hepatitis E virus (HEV) capsid by constructing, clustering and characterizing a tool box, Journal of Biological Chemistry, 2015, 290(32): 19910-19922 (Co-Corresponding author) Tang, Zi-Min#; Tang, Ming#; Zhao, Min; Wen, Gui-Ping; Yang, Fan; Cai, Wei; Wang, Si-Ling; Zheng, Zi-Zheng*; Xia, Ning-Shao*. A novel linear neutralizing epitope of hepatitis E virus. Vaccine, 2015.7.9, 33(30): 3504~3511 (Co-Corresponding author)
