个人简历

教育经历
2005.09-2009.07聊城大学化学化工学院，获学士学位（化学工程与工艺）
2009.09-2014.12南京理工大学环境与生物工程学院，获博士学位（化学工程与技术）

研究领域

天然产物及其类似物的抗炎药理学研究"承担科研项目情况
1.国家自然科学基金青年项目（81503123，2016/01-2018/12，主持）
2.浙江省自然科学基金（LQ14H310003，2014/01-2016/12，主持）"

近期论文

1.XiaoouShan#,YaliZhang#,HongjinChen#,LiliDong,BeibeiWu,TingtingXu,JieHu,ZhiguoLiu,WeiWang,LiqinWu,ZhiguoFeng*,GuangLiang*.InhibitionofepidermalgrowthfactorreceptorattenuatesLPS-inducedinflammationandacutelunginjuryinrats.Oncotarget,2017,accepted.(IF=5.008)
2.ZhenWang#,YaliZhang#,BartualSergio,JinfengLuo,TingtingXu,WentingDu,QiujuXun,ZhengchaoTu,BrekkenRolf,Xiaomeiren,BullockAlex,GuangLiang*,XiaoyunLu*,KeDing*.Tetrahydroisoquinoline-7-carboxamideDerivativesasNewSelectiveDiscoidinDomainReceptor1(DDR1)Inhibitors.ACSMedicinalChemistryLetters,2017,accepted.(IF=3.355)
3.YaliZhang#,TingtingXu#,BeibeiWu#,HongjinChen,ZheerPan,YiHuang,LiqinMei,YuanrongDai,XingLiu*,XiaoouShan*,GuangLiang*.Targetingmyeloiddifferentiationprotein2(MD-2)bythenewchalconeL2H21protectsLPS-inducedacutelunginjury.JournalofCellularandMolecularMedicine,2017,21(4):746-757.(IF=4.938)
4.YaliZhang,JianzhangWu,ShilongYing,GaozhiChen,BeibeiWu,TingtingXu,ZhiguoLiu,XingLiu,LehaoHuang,XiaoouShan,YuanrongDai,GuangLiang*.DiscoveryofnewMD2inhibitorfromchalconederivativeswithanti-inflammatoryeffectsinLPS-inducedacutelunginjury.ScientificReports,2016,6:25130.(IF=5.228)
5.ZhiguoLiu#,LongguangTang#,HepingZhu#,TingtingXu,ChenyuQiu,SuqingZheng,YuguiGu,JianpengFeng,YaliZhang*,GuangLiang*.Design,synthesisandstructure-activityrelationshipstudyofnovelindole-2-carboxamidederivativesasanti-inflammatoryagentsforthetreatmentofsepsis.JournalofMedicinalChemistry,2016,59(10):4637-50.(IF=5.589)