个人简历

刘玉兰，1975年2月出生，博士，武汉轻工大学动物科学与营养工程学院教授，动物营养与饲料科学湖北省重点实验室主任，硕士生导师，从事动物营养与饲料科学方面的教学科研工作。在猪的营养与免疫、肠道生理机能调控方面做了大量系统深入的研究工作。她是国家自然科学基金优秀青年科学基金获得者（2014）、湖北省自然科学基金杰出青年基金获得者（2013），入选第二批国家“万人计划”领军人才（科技创新领军人才）（2016）、享受国务院政府特殊津贴人员（2016）、国家百千万人才工程（授予“国家有突出贡献中青年专家”）（2015）、科技部中青年科技创新领军人才（2014）、湖北省有突出贡献中青年专家（2014）、湖北省新世纪高层次人才工程第二层次人选（2011）、教育部新世纪优秀人才支持计划（2010）。目前主持或主持完成国家自然科学基金项目6项，其他省部级项目20项，作为重要学术骨干参与国家973项目2项，国家重点研发计划1项。发表学术论文100余篇，以第一或通讯作者在《TheJournalofNutrition》、《JournalofNutritionalBiochemistry》等著名期刊上发表SCI论文51篇。为中国畜牧兽医学会动物营养学分会常务理事、中国畜牧兽医学会高级会员、湖北省畜牧兽医学会理事。应邀担任《TheJournalofNutrition》、《JournalofNutritionalBiochemistry》、《BritishJournalofNutrition》、《JournalofAnimalScience》等30余SCI期刊的审稿专家。获第十届湖北省青年科技奖，湖北省科技进步一等奖、二等奖和武汉市自然科学优秀学术论文一等奖各1项，授权/申报国家发明专利14项。副主编或参编专著6部。成果鉴定2项。

一、教育经历
2000/09-2003/07，中国农业大学，动物科技学院，博士
1997/09-2000/07，华南农业大学，动物科学系，硕士
1993/09-1997/07，武汉食品工业学院，饲料科学系，学士

二、研究工作经历
2012/01-至今，武汉轻工大学（原武汉工业学院），动物科学与营养工程学院，教授
2010/02-2011/04，美国北卡罗莱纳州立大学（NorthCarolinaStateUniversity），动物科学系，访问学者
2006/01-2011/12，武汉工业学院，动物科学与营养工程学院，副教授
2003/07-2005/12，武汉工业学院，动物科学与营养工程学院，讲师

研究领域

1.猪的营养与免疫
2.猪胃肠道结构与功能的调控
3.饲料添加剂的研究与开发

近期论文

[1]LiuYL*,ChenF,LiQ,OdleJ,LinX,ZhuHL,HongY,HouYQ,YiD,ShiHF.2013.Fishoilalleviatesactivationofhypothalamic-pituitary-adrenalaxisassociatedwithinhibitionofTLR4andNODsignalingpathwaysinweaningpigsafteranLPSchallenge.TheJournalofNutrition.143:1799-1807.
[2]LiuYL*,ChenF,OdleJ,LinX,ZhuHL,ShiHF,HouYQ,YinJD.2013.FishoilincreasesmuscleproteinmassandmodulatesAkt/FOXO,TLR4andNODsignalinginweaningpigletsafterLPSchallenge.TheJournalofNutrition.143:1331-1339.
[3]LiuYL*,ChenF,OdleJ,LinX,JacobiSK,ZhuHL,WuZF,HouYQ.2012.FishoilenhancesintestinalintegrityandinhibitsTLR4andNOD2signalingpathwaysinweanedpigsafterLPSchallenge.TheJournalofNutrition.142:2017-2024.
[4]PiDA,LiuYL*,ShiHF,LiS,OdleJ,LinXi,ZhuHL,ChenF,HouYQ,LengWB.2014.Dietarysupplementationofaspartateenhancesintestinalintegrityandenergystatusinweanlingpigletsafterlipopolysaccharidechallenge.JournalofNutritionalBiochemistry.25:456-462.
[5]LengWB,LiuYL*,ShiHF,LiS,ZhuHL,PiDA,HouYQ,GongJH.2014.AspartatealleviatesliverinjuryandregulatesmRNAexpressionsofTLR4andNODsignalingrelatedgenesinweanedpigsafterlipopolysaccharidechallenge.JournalofNutritionalBiochemistry.25:592-599.
2.其他论文
[6]ZhangJ,XuX,ZhangL,LiuY,OdleJ,LinX,ZhuHL,WangXY,LiuYL*.2019.EPAandDHAinhibitmyogenesisanddownregulatetheexpressionofmuscle-relatedgenesinC2C12myoblasts.Genes.DOI:10.3390/genes10010064
[7]WangXY#,WangWJ#,WangLM,YuC,ZhangGL,ZhuHL,WangCW,ZhaoSJ,HuCA,LiuYL*.2019.Lentinanmodulatesintestinalmicrobiotaandenhancesbarrierintegrityinapigletmodelchallengedwithlipopolysaccharide.Food&Function.10:479-489.
[8]ZhangJ,XuX,ZhuHL,WangY,HouYQ,LiuYL*.2019.DietaryfishoilsupplementationalterslivergeneexpressionstoprotectagainstLPS-inducedliverinjuryinweanlingpiglets.InnateImmunity.25:60-72.
[9]ZhangL#,WangXY#,ChenSK,WangSH,TuZX,ZhangGL,ZhuHL,LiXG,XiongJL,LiuYL*.2018.Medium-chaintriglyceridesattenuateliverinjuryinlipopolysaccharide-challengedpigsbyinhibitingnecroptoticandinflammatorysignalingpathways.InternationalJournalofMolecularSciences.19:3697.
[10]QinQ#,XuX#,WangXY,WuHT,ZhuHL,HouYQ,DaiB,LiuXT,LiuYL*.2018.Glutamatealleviatesintestinalinjury,maintainsmTORandsuppressesTLR4andNODsignalingpathwaysinweanlingpigschallengedwithlipopolysaccharide.ScientificReports.8:15124.
[11]XuX,WangXY,WuHT,ZhuHL,LiuCC,HouYQ,DaiB,LiuXT,LiuYL*.2018.GlycinerelievesintestinalinjurybymaintainingmTORsignalingandsuppressingAMPK,TLR4andNODsignalinginweanedpigletsafterlipopolysaccharidechallenge.InternationalJournalofMolecularSciences.19:1980.
[12]WangLM,TuZX,WangHB,WangSH,WangXY,ZhuHL,HuCA,LiuYL*.2018.Flaxseedoilimprovesliverinjuryandinhibitsnecroptoticandinflammatorysignalingpathwaysfollowinglipopolysaccharidechallengeinapigletmodel.JournalofFunctionalFoods.46:482-489.
[13]ZhuHL,WangHB,WangSH,TuZX,ZhangL,WangXY,HouYQ,WangCW,QinQ,ChenJ,LiuYL*.2018.FlaxseedoilattenuatesintestinaldamageandinflammationbyregulatingnecroptosisandTLR4/NODsignalingpathwaysfollowinglipopolysaccharidechallengeinapigletmodel.MolecularNutrition&FoodResearch.62:e1700814.
[14]XuX,ChenSK,WangHB,TuZX,WangSH,WangXY,ZhuHL,WangCW,ZhuJD,LiuYL*.2018.Medium-chainTAGimproveintestinalintegritybysuppressingtoll-likereceptor4,nucleotide-bindingoligomerisationdomainproteinsandnecroptosissignallinginweanlingpigletschallengedwithlipopolysaccharide.BritishJournalofNutrition.119:1019-1028.
[15]KangP,LiuYL*,ZhuHL,ZhangJ,ShiHF,LiS,PiDA,LengWB,WangXY,WuHT,HouYQ.2018.Theeffectofdietaryasparaginesupplementationonenergymetabolisminliverofweaningpigswhenchallengedwithlipopolysaccharide.Asian-AustralasianJournalofAnimalSciences.31:548-555.
[16]LiuYL*,WangXY,HuCA*.2017.Therapeuticpotentialofaminoacidsininflammatoryboweldisease.Nutrients.9:pii:E920.
[17]KangP,WangXY,WuHT,ZhuHL,HouYQ,WangLM,LiuYL*.2017.GlutamatealleviatesmuscleproteinlossbymodulatingTLR4,NODs,Akt/FOXOandmTORsignalingpathwaysinLPS-challengedpiglets.PLoSOne.12:e0182246.
[18]ZhuHL,PiDA,LengWB,WangXY,HuCA,HouYQ,XiongJL,WangCW,QinQ,LiuYL*.2017.AsparaginepreservesintestinalbarrierfunctionfromLPS-inducedinjuryandregulatesCRF/CRFRsignalingpathway.InnateImmunity.23:546-556.
[19]LiuYL*,WangXY,HouYQ,YinYL,QiuYS,WuGY,HuCA*.2017.Rolesofaminoacidsinpreventingandtreatingintestinaldiseases:recentstudieswithpigmodels.AminoAcids.49:1277-1291.
[20]GuoL,LiuYL*,HanJ,ZhuHL,WangXY.2017.EffectsofbiotiteVsupplementationongrowthperformanceandtheimmunologicalresponsesofweanedpigsafteranEscherichiacolilipopolysaccharidechallenge.LivestockScience195:112-117.
[21]SunLH,PiDA,ZhaoL,WangXY,ZhuLY,QiDS,LiuYL*.2017.ResponseofseleniumandselenogenomeinimmunetissuestoLPS-inducedinflammatoryreactionsinpigs.BiologicalTraceElementResearch.177:90-96.
[22]ZhangJ,LiuY*.2017.MicroRNAinskeletalmuscle:Itscrucialrolesinsignalproteins,musclefibertype,andmuscleproteinsynthesis.CurrentProteinandPeptideScience.18:579-588.
[23]LiuYL*,WangXY,LengWB,PiDA,TuZX,ZhuHL,ShiHF,LiS,HouYQ,HuCA.2017.AspartateinhibitsLPS-inducedMAFbxandMuRF1expressioninskeletalmuscleinweanedpigsbyregulatingAkt,AMPKαandFOXO1.InnateImmunity.23:34-43.
[24]ChenSK,LiuYL*,WangXY,WangHB,LiS,ShiHF,ZhuHL,ZhangJ,PiDA,HuCA,LinX,OdleJ.2016.Asparagineimprovesintestinalintegrity,inhibitsTLR4andNODsignaling,anddifferentlyregulatesp38andERK1/2signalinginweanlingpigletsafterLPSchallenge.InnateImmunity.22:577-587.
[25]WangXY,LiuYL*,WangSH,PiDA,LengWB,ZhuHL,ZhangJ,ShiHF,LiS,LinX,OdleJ.2016.AsparaginereducesthemRNAexpressionofmuscleatrophymarkersviaregulatingAkt,AMP-activatedproteinkinaseα,toll-likereceptor4andnucleotide-bindingoligomerisationdomainproteinsignallinginweaningpigletsafterlipopolysaccharidechallenge.BritishJournalofNutrition.116:1188-1198.
[26]LiuYL*,WangX,WuH,ChenS,ZhuH,ZhangJ,HouY,HuCA,ZhangG.2016.GlycineenhancesmuscleproteinmassassociatedwithmaintainingAkt-mTOR-FOXO1signalingandsuppressingTLR4andNOD2signalinginpigletschallengedwithLPS.AmericanJournalofPhysiology-RegulatoryIntegrativeandComparativePhysiology.311:R365-R373.
[27]WangHB,LiuYL*,ShiHF,WangXY,ZhuHL,PiDA,LengWB,LiS.2017.AspartateattenuatesintestinalinjuryandinhibitsTLR4andNODs/NF-κBandp38signalinginweanedpigsafterLPSchallenge.EuropeanJournalofNutrition.56:1433-1443.
[28]ZhuHL,LiuYL*,ChenSK,WangXY,PiDA,LengWB,ChenF,ZhangJ,KangP.2016.Fishoilenhancesintestinalbarrierfunctionandinhibitscorticotropin-releasinghormone/corticotropin-releasinghormonereceptor1signallingpathwayinweanedpigsafterlipopolysaccharidechallenge.BritishJournalofNutrition.115:1947-1957.
[29]LiuYL*.2015.Fattyacids,inflammationandintestinalhealthinpigs.JournalofAnimalScienceandBiotechnology.6:41.
[30]ZhangJ,FuSL,LiuY,LiuYL*,WangWJ*.2015.AnalysisofmicroRNAexpressionprofilesinweanedpigskeletalmuscleafterlipopolysaccharidechallenge.InternationalJournalofMolecularSciences.16:22438-22455.
[31]WangX,LiuY*,LiS,PiD,ZhuH,HouY,ShiH,LengW.2015.Asparagineattenuatesintestinalinjury,improvesenergystatus,andinhibitsAMPKsignalingpathwaysinweanedpigletschallengedwithEscherichiacolilipopolysaccharide.BritishJournalofNutrition.114:553-565.
[32]WuH,LiuY*,PiD,LengW,ZhuH,HouY,LiS,ShiH,WangX.2015.AsparagineattenuateshepaticinjurycausedbylipopolysaccharideinweanedpigletsassociatedwithmodulationofTLR4andNODsignalingandtheirnegativeregulators.BritishJournalofNutrition.114:189-201.
[33]KangP,LiuYL*,ZhuHL,LiS,ShiHF,ChenF,LengWB,PiDA,HouYQ,YiD.2015.Theeffectofaspartateontheenergymetabolismintheliverofweanlingpigschallengedwithlipopolysaccharide.EuropeanJournalofNutrition.54:581-588.
[34]ZhuHL,LiuYL*,XieXL,HuangJJ,HouYQ.2013.EffectofL-arginineonintestinalmucosalimmunebarrierfunctioninweanedpigsafterEscherichiacoliLPSchallenge.InnateImmunity.19:242-252.
[35]ChenF,LiuYL*,ZhuHL,HongY,WuZF,HouYQ,LiQ,DingBY,YiD,ChenHB.2013.FishoilattenuatesliverinjurycausedbyLPSinweanedpigsassociatedwithinhibitionofTLR4andNODsignalingpathways.InnateImmunity.19:504-515.
[36]LiQ,LiuYL*,CheZQ,ZhuHL,MengGQ,HouYQ,DingBY,YinYL,ChenF.2012.DietaryL-argininesupplementationalleviatesliverinjurycausedbyEscherichiacoliLPSinweanedpigs.InnateImmunity.18:804-814.
[37]CheZQ,LiuYL*,WangHR,ZhuHL,HouYQ,DingBY.2011.Theprotectiveeffectsofdifferentmycotoxinadsorbentsagainstbloodandliverpathologicalchangesinducedbymold-contaminatedfeedinbroilers.Asian-AustralasianJournalofAnimalSciences.24:250-257.
[38]LiuYL*,MengGQ,WangHR,ZhuHL,HouYQ,WangWJ,DingBY.2011.Effectofthreemycotoxinadsorbentsongrowthperformance,nutrientdigestibilityandmeatqualityinbroilersfedmold-contaminatedfeed.BritishPoultryScience.52:255-263.
[39]FanW,LiuYL*,WuZF,HongY,ZhuHL,HouYQ,YinYL,HanJ.2010.Effectsofrosiglitazone,anagonistoftheperoxisomeproliferator-activatedreceptorgamma,onintestinaldamageinducedbyEscherichiacolilipopolysaccharideinweanedpigs.AmericanJournalofVeterinaryResearch.71:1331-1338.
[40]LiuYL*,ShiJX,LuJ,CheZQ,ZhuHL,HouYQ,YinYL,ZhaoSJ,DingBY,LiuHM.2010.Up-regulatedexpressionoftheperoxisomeproliferator-activatedreceptorγinhypothalamic–pituitary-adrenalaxisofweanedpigsafterEscherichiacolilipopolysaccharidechallenge.TheVeterinaryJournal.184:230-235.
[41]LiuYL*,ShiJX,LuJ,MengGQ,ZhuHL,HouYQ,YinYL,ZhaoSJ,DingBY.2009.Activationofperoxisomeproliferator-activatedreceptorγpotentiatespro-inflammatorycytokineproduction,andadrenalandsomatotropicchangesofweanedpigsafterEscherichiacolilipopolysaccharidechallenge.InnateImmunity.15:169-178.
[42]LiuYL,HanJ,HuangJJ,WangXQ,WangFL,WangJJ*.2009.DietaryL-argininesupplementationimprovesintestinalfunctioninweanedpigsafteranEscherichiacolilipopolysaccharide.Asian-AustralasianJournalofAnimalSciences.22:1667-1675.
[43]HanJ,LiuYL*,FanW,ChaoJ,HouYQ,YinYL,ZhuHL,MengGQ,CheZQ.2009.DietaryL-argininesupplementationalleviatesimmunosuppressioninducedbycyclophosphamideinweanedpigs.AminoAcids.37:643-651.
[44]GuoGL,LiuYL*,FanW,HanJ,HouYQ,YinYL,ZhuHL,DingBY,ShiJX,LuJ,WangHR,ChaoJ,QuYH.2008.Effectsofachyranthesbidentatapolysaccharideongrowthperformance,immunological,adrenal,andsomatotropicresponsesofweanedpigschallengedwithEscherichiacolilipopolysaccharide.Asian-AustralasianJournalofAnimalSciences.21:1189-1195.
[45]LiuYL*,HuangJJ,HouYQ,ZhuHL,ZhaoSJ,DingBY,YinYL,YiGF,ShiJY,FanW.2008.DietaryargininesupplementationalleviatesintestinalmucosaldisruptioninducedbyEscherichiacolilipopolysaccharideinweanedpigs.BritishJournalofNutrition.100:552-560.
[46]LiuYL*,LuJ,ShiJX,HouYQ,ZhuHL,ZhaoSJ,LiuHM,DingBY,YinYL,YiGF.2008.Increasedexpressionoftheperoxisomeproliferator-activatedreceptorγintheimmunesystemofweanedpigsafterEscherichiacolilipopolysaccharidechallenge.VeterinaryImmunologyandImmunopathology.124:82-92.
[47]LiuYL*,YiGF,SongGL,HouYQ,HuangJW,Vazquez-AnonM,KnightCD.2007.Impactoffeeding2-hydroxy-4-(methylthio)butanoicacidandDL-methioninesupplementedmaize-soyabean-rapeseedmealdietsongrowthperformanceandcarcassqualityofbroilers.BritishPoultryScience.48:190-197.
[48]LiuYL*,SongGL,YiGF,HouYQ,HuangJW,Vazquez-AnonM,KnightCD.2006.Effectofsupplementing2-hydroxy-4-(methylthio)butanoicacidandDL-methionineincorn-soybean-cottonseedmealdietsongrowthperformanceandcarcassqualityofbroilers.Asian-AustralasianJournalofAnimalSciences.19:1197-1205.
[49]HouYQ,LiuYL*,HuJ,ShenWH.2006.Effectsoflactitolandtributyrinongrowthperformance,smallintestinalmorphologyandenzymeactivityinweanedpigs.Asian-AustralasianJournalofAnimalSciences.19:1470-1477.
[50]LiuYL,LiDF*,GongLM,YiGF,GainesAM,CarrollJA.2003.Effectsoffishoilsupplementationontheperformanceandtheimmunological,adrenal,andsomatotropicresponsesofweanedpigsafteranEscherichiacolilipopolysaccharidechallenge.JournalofAnimalScience.81:2758-2765.
[51]LiuYL,GongLM*,LiDF,FengZY,ZhaoLD,DongT.2003.Effectsoffishoilonlymphocyteproliferation,cytokineproductionandintracellularsignalinginweanlingpigs.ArchivesofAnimalNutrition.57:151-165.