个人简历

廖兴华
性别：男
出生年月：198411
民族：汉
政治面貌：中共党员
职称职务：副教授
教育经历：
2004，9-2008，6
天津科技大学
制药工程专业，学士;
2008，9-2011，6
天津科技大学
药物化学专业，硕士;
2012，9-2015，6
天津科技大学
发酵工程专业，博士

研究领域

1）乳腺癌的迁移与侵袭及表观遗传学修饰；2）心肌肥厚及心肌纤维化的发病机制；3）重要转录因子在血液疾病中的转录调控作用。"肿瘤发病机制，心血管疾病发病机制，表观遗传学"

近期论文

2018
1Jia-PengLi1,Xing-HuaLiao1*,YuanXiang1,AoYao,Li-JuanFan,HuiLi,Zi-JianZhang,FengHuang,Zhou-TongDai,Tong-CunZhang*MKL1/miR34a/FOXP3axisregulatescellproliferationingastriccancer.JournalofCellularBiochemistry.2018Nov13.doi:10.1002/jcb.28056.

2AoYao1,YuanXiang1,Yu-RuiSi1,Li-JuanFan,Jia-PengLi,HuiLi,WeiGuo,Hui-XinHe,Xing-JieLiang,Le-YuanBao*,Xing-HuaLiao*.
PKM2promotesglucosemetabolismthroughalet-7a-5p/stat3/hnRNP-A1regulatoryfeedbackloopinbreastcancercells.JournalofCellularBiochemistry.2019Apr;120(4):6542-6554.

3Jia-PengLi1,Xing-HuaLiao1*,YuanXiang1,AoYao,Ru-HuiSong,Zi-JianZhang,FengHuang,Zhou-TongDai,Tong-CunZhang*Hyperosideandlet-7a-5psynergisticallyinhibitslungcancercellproliferationviainducingG1/Sphasearrest.Gene.2018Sep7;679:232-240.

4Jia-PengLi1,YuanXiang1,Li-JuanFan,AoYao,HuiLi,Xing-HuaLiao*.LongnoncodingRNAH19competitivelybindsmiR-93-5ptoregulateSTAT3expressioninbreastcancer.JournalofCellularBiochemistry.2019Mar;120(3):3137-3148.

5DengchengHuang,YuZhou,*YuanXiang,MeijieShu,HongxiangChen,BingYanga,andXinghuaLiao*.Polyurethane/doxorubicinnanoparticlesbasedonelectrostaticinteractionsaspH-sensitivedrugdeliverycarriers.PolymerInternational.2018September67(9),1186-1193.

2017

1YuanXiang#,Xing-HuaLiao#*,Jia-PengLi,HuiLi,HuanQin,AoYao,Cheng-XiYu,PengHu,WeiGuo,Chao-JiangGu*,Tong-CunZhang*.MyocardinandStat3actsynergisticallytoinhibitcardiomyocyteapoptosis.Oncotarget.2017Aug24;8(59):99612-99623.

2YuanXiang#,Xing-HuaLiao#*,AoYao,HuanQin,Li-JuanFan,Jia-PengLi,PengHu,HuiLi,WeiGuo,Jun-YanLi,Chao-JiangGu,Le-YuanBao*,Tong-CunZhang*MRTF-A-miR-206-WDR1formfeedbacklooptoregulatebreastcancercellmigration.ExperimentalCellResearch.2017Oct15359（2）394–404.

3YuanXiang#,Xing-HuaLiao#*,Cheng-XiYu,AoYao,HuanQin,Jia-PengLi,PengHu,HuiLi,WeiGuo,Chao-JiangGu,Tong-CunZhang*.MiR-93-5pinhibitstheEMTofbreastcancercellsviatargetingMKL-1andSTAT3ExperimentalCellResearch.2017Aug1;357(1):135-144.

4XingHuaLiao#*,YuanXiang#,HuiLi#,DeLiangZheng,YaoXu,ChengXiYu,JiaPengLi,XiaoYuZhang,WeiBinXing,DongSunCao,LeYuanBao,TongCunZhang*.VEGF-AStimulatesSTAT3ActivityviaNitrosylationofMyocardintoRegulatetheExpressionofVascularSmoothMuscleCellDifferentiationMarkersScientificReports.2017Jun1;7(1):2660.

5Xing-HuaLiao#,*,YuanXiang#,Cheng-XiYu#,Jia-PengLi,HuiLi,QiNie,PengHu,JunZhou,Tong-CunZhang*.STAT3isrequiredforMiR-17-5p-mediatedsensitizationtochemotherapy-inducedapoptosisinbreastcancercells.Oncotarget.2017Feb28;8(9):15763-15774.

6HuiLi#,YuanXiang#,Li-JuanFan,Xiao-YuZhang,Jia-PengLi,Cheng-XiYu,Le-YuanBao,Dong-SunCao,Wei-BingXing,Xing-HuaLiao*,Tong-CunZhang*.Myocardininhibitedthegapproteinconnexin43viapromotedmiR-206toregulatevascularsmoothmusclecellphenotypicswitch.Gene.2017Jun15;616:22-30

7Xing-HuaLiao#*,Jun-YanLi#,Xiu-MeiDong,XiuhongWang,YuanXiang,HuiLi,Cheng-XiYu,Jia-PengLi,Bai-YinYuan,JunZhou*,Tong-CunZhang*.ERαinhibitedmyocardin-induceddifferentiationinuterinefibroids.ExperimentalCellResearch.2017Jan1;350(1):73-82.

2016
1XiangY#,LuDL#,LiJP,YuCX,ZhengDL,HuangX,WangZY,HuP,LiaoXH*,ZhangTC*.Myocardininhibitsestrogenreceptoralpha-mediatedproliferationofhumanbreastcancerMCF-7cellsviaregulatingMicroRNAexpression.IUBMBLife.2016Jun;68(6):477-87.(共同通讯作者)

2015
1LiaoXH#,ZhengL#,HeHP#,ZhengDL,WeiZQ,WangN,DongJ,MaWJ*,ZhangTC*.STAT3regulatedATRviamicroRNA-383tocontrolDNAdamagetoaffectapoptosisinA431cells.CellSignal.2015Nov;27(11):2285-95.

2LiaoXH#,WangN#,ZhaoDW,ZhengDL,ZhengL,XingWJ,MaWJ,BaoLY,DongJ,ZhangTC*.STAT3ProteinRegulatesVascularSmoothMuscleCellPhenotypicSwitchbyInteractionwithMyocardin.JBiolChem.2015Aug7;290(32):19641-52.

3Wen-JingXing#,Xing-HuaLiao#,NanWang#,Dong-WeiZhao,LiZheng,De-LiangZheng,JianDong*,Tong-CunZhang*.MRTF-AandSTAT3promoteMDA-MB-231cellmigrationviahypermethylatingBRSM1.IUBMBLife2015;67(3):202-17.

4Liweizhong#,Wangnan#*,Liman,Gonghuiqin,Liaoxinghua,Yangxiaolong,Zhangtongcun*.ProteinkinaseCαinhibitsmyocardin-inducedcardiomyocytehypertrophythroughthepromotionofmyocardinphosphorylation.ActaBiochimBiophysSin(Shanghai).2015Sep;47(9):687-95.

5LiM#,WangN#*,GongHQ,LiWZ,LiaoXH,YangXL,HeHP,CaoDS,ZhangTC*.Ca2+signal-inducedcardiomyocytehypertrophythroughactivationofmyocardin.Gene.2015;557:43-51.

2014
1Xing-HuaLiao#,NanWang#*,Dong-WeiZhao,De-LiangZheng,LiZheng,Wen-JingXing,HaoZhou,Dong-SunCao,Tong-CunZhang*.NF-B(p65)negativelyregulatesmyocardin-inducedcardiomyocytehypertrophythroughmultiplemechanisms.CellSignal2014;26(12):2738-2748

2Xing-HuaLiao#,NanWang#*,Long-YueLiu,LiZheng,Wen-JingXing,Dong-WeiZhao,Xue-GuangSun,PengHu,JianDong,Tong-CunZhang*.MRTF-AandSTAT3synergisticallypromotebreastcancercellmigration.CellSignal2014,26(11):2370-2380

3Xing-HuaLiao#,Da-LinLu#,NanWang#*,Long-YueLiu,YueWang,Yan-QiLi,Ting-BaoYan,Xue-GuangSun,PengHuandTong-CunZhang*.EstrogenreceptorαmediatesproliferationofbreastcancerMCF–7cellsviaap21/PCNA/E2F1-dependentpathway.FEBSJournal2014;281(3):927-42.

4Xing-HuaLiao#,Yan-QiLi#,NanWang#*,Lizheng,Wen-JingXing,Dong-WeiZhao,Ting-BaoYan,YueWang,Long-YueLiu,Xue-GuangSun,PengHu,HaoZhou,Tong-CunZhang*.Re-expressionandepigeneticmodificationofmaspininducedapoptosisinMCF-7cellsmediatedbymyocardin.CellSignal2014;26(6)1335–1346

5Xing-HuaLiao#,YueWang#,NanWang#*,Ting-BaoYan,Wen-JingXing,LiZheng,Dong-WeiZhao,Yan-QiLi,Long-YueLiu,Xue-GuangSun,PengHu,Tong-CunZhang*.Humanchorionicgonadotropin(hCG)decreaseshumanbreastcancercellproliferationandpromotesdifferentiation.IUBMBLife2014;66(5):352-60.

6Xing-HuaLiao#,XiumeiDong#,ChenyuWu,TaoWang,FenyongLiu,JunZhou*,Tong-CunZhang*.Humancytomegalovirusimmediateearlyprotein2enhancesmyocardin-mediatedsurvivalofrataorticsmoothmusclecells.VirusResearch.2014;192:85-91.

2013
1ZhipengLiu#,XueguangLuo#,LeiLiu,WenwenZhao,ShuGuo,YuGuo,NanWang,HongpengHe,XinghuaLiao,WenjianMa,HaoZhou,TongcunZhang.Histoneacetyltransferasep300promotesMKL1-mediatedtransactivationofcatechol-O-methyltransferasegene.ActaBiochimicaetBiophysicaSinica2013;45(12):1002-10.

2011
1Xing-HuaLiao#,NanWang#,Qing-XiLiu,TaoQin,BoCao,Dong-SunCaoandTong-CunZhang*.Myocardin-relatedtranscriptionfactor-Ainducescardiomyocytehypertrophy.IUBMBLife,2011;63(1):54-61

2JunZhou#,Xing-HuaLiao#,JunyanLi，ChenyuWu，RuiXiao，CailianCheng，DongsunCao,NanWang,TongcunZhang.ThesynergisticeffectsofcytomegalovirsusIEsandmyocardinoncardiomyocytehypertrophyandapoptosis.FEBSLetter,2011,5851082-1088

2010
15CaoXiaohong,CuiYunqian,LiaoXinghua,ZhouGuangtian,LeoThamm.GenecloningofphenolicaciddecarboxylasefromBacillussubtilisandexpressionintop-fermentingyeaststrains.Africanjournalofbiotechnology.2010,9(33):5284-5291

2009
1NanWang,ZhenZhou,XinghuaLiaoandTongcunZhang.RoleofmicroRNAsincardiachypertrophyandheartfailure.IUBMBLife,2009Jun;61(6):566-71