个人简历

学习经历\r
1992-1996，武汉大学生物系, 学士\r
1996-1999，华南农业大学植物细胞分子生物学，硕士\r
2000-2005，凯西西储大学Case Western Reserve University，药理系，博士\r
2005－2007，凯西西储大学Case Western Reserve University，医学系，博士后\r
\r
主要工作经历与任职\r
2008－现在，教授，武汉大学生命科学学院。\r
2007-2008， 讲师，凯西西储大学Case Western Reserve University，医学系

研究领域

""利用细胞模型与动物模型，研究糖尿病及其并发症，器官缺血再灌注的发病机理，病变过程，以及治疗""""

近期论文

Li J, Lu D, Dou H, Liu H, Weaver K, Wang W, Li J, Yeh ETH, Williams BO, Zheng L*, Yang T* . Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway. Nature communications. 2018; 9(1):143.\r
\r
Wan D, Liu C, Sun Y, Wang W, Huang K*, Zheng L*. MacroH2A1.1 cooperates with EZH2 to promote adipogenesis by regulating Wnt signaling. Journal of molecular cell biology. 2017; 9(4):325-337.\r
\r
Liu S, Sun Y, Jiang M, Li Y, Tian Y, Xue W, Ding N, Sun Y, Cheng C, Li J, Miao X, Liu X, Zheng L* and Huang K*. Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase. Hepatology. 2017; 66(2):631-645.\r
\r
Wang W, Wang Q, Wan D, Sun Y, Wang L, Chen H, Liu C, Petersen RB, Li J, Xue W, Zheng L* and Huang K*. Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy. Autophagy. 2017; 13(5):941-954.\r
\r
Sun Y, Xue W, Song Z, Huang K* and Zheng L*. Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration. Journal of molecular medicine. 2016; 94(3):335-346.\r
\r
Huang J, Wan D, Li J, Chen H, Huang K and Zheng L*. Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury. Epigenetics. 2015; 10(1):62-72.\r
\r
Cai R, Xue W, Liu S, Petersen RB, Huang K and Zheng L*. Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury. FASEB journal. 2015; 29(7):2749-2758.\r
\r
Ding Y#, Li J#, Liu S, Zhang L, Xiao H, Li J, Chen H, Petersen RB, Huang K* and Zheng L*. DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding. International journal of obesity. 2014; 38(2):198-204.\r
\r
Li J, Huang J, Li JS, Chen H, Huang K* and Zheng L*. Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. Journal of hepatology. 2012; 56(4):900-907.\r
\r
Zheng L*, Du Y, Miller C, Gubitosi-Klug RA, Ball S, Berkowitz BA and Kern TS*. Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes. Diabetologia. 2007; 50(9):1987-1996.\r
\r
Zheng L, Howell SJ, Hatala DA, Huang K and Kern TS. Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes. 2007; 56(2):337-345.\r
\r
Zheng L, Szabo C and Kern TS. Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. Diabetes. 2004; 53(11):2960-2967.