舒红兵
近期热点
资料介绍
个人简历
教育经历\r1983-1987 兰州大学生物学系动物学专业,学士\r1987-1990 中国医学科学院基础医学研究所细胞生物学研究室,硕士\r1992-1995 美国Emory大学细胞及发育生物学专业,博士\r1995-1997 美国Tularik公司(后并入Amgen公司)David Goeddel实验室,博士后\r\r工作经历与任职\r1990-1992 美国密西根大学医学中心,研究助理\r1997-1998 美国Magainin制药公司,资深科学家\r1998-2003 美国犹太医学研究中心及科罗拉多大学健康科学中心免疫学系,助理教授\r2003-2005 美国犹太医学研究中心及科罗拉多大学健康科学中心免疫学系,副教授\r2005-2013 武汉大学生命科学学院,教授、院长\r2013- 武汉大学副校长,武汉大学生命科学学院教授研究领域
""抗病毒天然免疫""""近期论文
Wang YY, Liu LJ, Zhong B, Liu TT, Li Y, Yang Y, Ran Yong, Li S, Tien P, Shu HB* (2010). WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kB activation. P Natl Acad Sci USA 107:815-820.\r\rLi S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu, HB* (2010). Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. J Biol Chem 285:4291-4297.\r\rMao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB* (2010). Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response. J Biol Chem 285:9470-9476.\r\rHan KJ, Yang Y, Xu LG, Shu HB* (2010). Analysis of a TIR-less splice variant of TRIF reveals an unexpected mechanism of TLR3-mediated signaling. J Biol Chem 285:12543-12550.\r\rChen R, Zhang L, Zhong B, Tan B, Liu Y, Shu HB* (2010). The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling. Cell Res 20:802-811.\r\rZhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB* (2010). The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. J Immunol 184:6249-6255.\r\rLei CQ, Zhong B, Zhang Y, Zhang J, Shu HB* (2010). GSK3b regulates virus-triggered IRF3 activation and cellular antiviral response by promoting TBK1 activation. Immunity 33:878-889.\r\rLi Q, Yan J, Mao AP, Li C, Ran Y, Shu HB*, Wang YY * (2011). Tripartite motif 8 (TRIM8) modulates TNFa- and IL-1b-triggered NF-kB activation by targeting TAK1 for K63-linked polyubiquitination. P Natl Acad Sci USA 108:19341-19346.\r\rRan Y, Liu TT, Zhou Q, Li S, Mao AP, Li Y, Liu LJ, Cheng JK, Shu HB* (2011). SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. J Mol Cell Biol 2:283-292.\r\rLiu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB* (2012). Protein kinase C-δ negatively regulates T cell receptor-induced NF-kB activation by inhibiting the assembly of CARMA1 signalosome. J Biol Chem 287:20081-20087.\r\rHe X, Li Y, Li C, Liu LJ, Zhang XD, Liu Y, Shu HB* (2012).USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6. J Mol Cell Biol 5:39-47.\r\rZhang J, Hu MM, Wang YY, Shu HB* (2012). TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination. J Biol Chem 287:28646-28655.\r\rLi Y, Chen R, Zhou Q, Xu Z, Li C, Wang S, Mao A, Zhang X, He W, Shu HB* (2012). LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. P Natl Acad Sci USA 109:11770-11775.\r\rWang YY *, Ran Y, Shu HB* (2012).Linear ubiquitination of NEMO brakes the antiviral response. Cell Host Microbe 12:129-131.\r\rChen R, Li M, Zhang Y, Zhou Q, Shu HB* (2012). The E3 ubiquitin ligase MARCH8 negatively regulates IL-1β-induced NF-κB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation. P Natl Acad Sci USA 109:14128-14133.\r\rZheng H, Li Q, Chen R, Zhang J, Ran Y, He X, Li S, Shu HB* (2012).Dual-specificity phosphatase 14 (DUSP14) negatively regulates TNF-a and IL-1-induced NF-κB activation by dephosphorylating the protein kinase TAK1. J Biol Chem 288:819-825.\r\rYang Y, Liao B, Wang S, Jin Y, Shu HB*, Wang YY*. (2013). The E3 ubiquitin ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation. PNAS 110(13):5115-20.\r\rLi C, Wei J, Li Y, He X, Zhou Q, Yan J, Zhang J, Liu Y, Liu Y, Shu HB* (2013). Transmembrane protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase-4 activation and apoptosis. J Biol Chem\r\rLei CQ, Zhang Y, Xia T, Jiang LQ, Zhong B, Shu HB* (2013). FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3. J Biol Chem 288:12596-12604.\r\rChen H, Li Y, Zhang J, Ran Y, Wei J, Yang Y, Shu HB* (2013). RAVER1 is a coactivator of MDA5-mediated cellular antiviral response. J Mol Cell Biol 5:111-119. 相关热点
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