个人简历

学习经历： 1994年获武汉大学理学学士学位， 2006年获得武汉大学理学博士学位， 2008.10-2010.9在美国国立卫生研究所做交流访问学者。 主要工作经历与任职 ： 1994-至今 武汉大学医学院

研究领域

朊病毒的功能与致病机理， DNA、RNA病毒病毒感染免疫与肿瘤的关系。

近期论文

1) Guihong Sun, Rachel A. Heimeier, Liezhen Fu, Takashi Hasebe, Biswajit Das,Atsuko Ishizuya-Oka, and Yun-Bo Shi. Expression profiling of intestinal tissues implicates tissue-specific genes and pathways essential for thyroid hormone-induced adult stem cell development. Endocrinology. 2013 Nov;154(11):4396-407. 2) Thomas C. Miller, Guihong Sun, Takashi Hasebe, Liezhen Fu, Rachel A. Heimeier, Biswajit Das, Atsuko Ishizuya-Oka, Yun-Bo Shi. Tissue-Specific Upregulation of MDS/EVI Gene Transcripts in the Intestine by Thyroid Hormone during Xenopus Metamorphosis. PLoS One. 8(1):e55585, 2013. 3) Guihong Sun*, Yun-Bo Shi*. Thyroid hormone regulation of adult intestinal stem cell development: mechanisms and evolutionary conservations. Int J Biol Sci. 8(8):1217-24, 2012. 4) Fanghua Mei , Jin Xiang, Song Han, Yuan He, Yajing Lu, Jian Xu, Deyin Guo, Gengfu Xiao, Po Tien, Guihong Sun*.Expression, purification, and secondary structure characterization of recombinant KCTD1. Biochemistry (Mosc). 77(8):941-5, 2012. 5) Liezhen Fu, Guihong Sun, Maria Fiorentino, Yun-Bo Shi. Characterization of Xenopus Tissue Inhibitor of Metalloproteinases-2: A role in regulating matrix metalloproteinase activity during development. PLoS One. 7(5):e36707, 2012. 6) Tao Huang, Jian Xu, Jin Xiang, Yajing Lu, Rui Chen, Liqin Huang, Gengfu Xiao, Guihong Sun. PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP51-136 region containing octapeptide repeats. Biochem Biophys Res Commun. 2012 Jan 6;417(1):182-6 7) Jin Xiang, Guihong Sun, Hui Liu, Yong-xin Mu, Ying Liu, Fang Yang, Jian Xu, and Hong Ding, Ritonavir stimulates foam cell formation by activating PKC, Chem. Bio. Interact. 2011, 194: 127-133. 8) Guihong Sun, Takashi Hasebe, Kenta Fujimoto, Rosemary Lu, Liezhen Fu, Hiroki Matsuda, Mitsuko Kajita, Atsuko Ishizuya-Oka, Yun-Bo Shi. Spatio-temporal expression profile of stem cell-associated gene LGR5 in the intestine during thyroid hormone-dependent metamorphosis in Xenopus laevis. PLoS ONE. 2010 Oct 22;5(10):e13605. 9) Guihong Sun, Biswajit Das, Liezhen Fu and Yun-Bo Shi. Temporal and Spatio-Regulation of Tissue-Specific Thyroid Hormone Response Genes during Intestinal Metamorphosis in Xenopus Laevis. Endocrine Reviews, Supplement 1, June 2010, 31[3]: S1477