个人简历
教育经历 2004.9--2008.6理学学士武汉大学生命科学学院生物学专业 管理学学士 武汉大学经济管理学院（第二学位） 2008.9--2013.6理学博士武汉大学生命科学学院细胞生物学专业 导师舒红兵 院士 工作经历： 2013.6--2015.5师资博士后武汉大学生命科学学院 2015.5--2017.11 讲师 武汉大学生命科学学院 2016.2--2017.8博士后MD Anderson Cancer Center, USA 导师 陈俊杰 教授 2017.11—今 副教授武汉大学生命科学学院
研究领域
1. 抗病毒天然免疫反应 2. DNA损伤诱导的免疫反应
近期论文
(1) Wang Junyong, Zeng Yan, Xu Shuai, Yang Jiayun, Wang Wanbing, Ge Jinying, Yin Lei, Wang Zhengxiang, Han Lu, Cui Xiaole, Zhong Bo, Shu Hongbing, Chen Hualan, Lei Caoqi*, Zhu Qiyun*, A naturally occurring deletion in the effector domain of H5N1 influenza virus nonstructural protein 1 regulates viral fitness and host innate immunity. Journal of Virology, 2018, 92(11): e00149-18 (2) Wang Junyong, Lei Caoqi*, Ji Yanhong, Zhou Hongbo, Ren Yujie, Peng Qianqian, Zeng Yan, Jia Yane, Ge Jinying, Zhong Bo, Li Yu, Wei Jianzhong, Shu Hongbing, Zhu Qiyun*, Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-beta Signaling Pathways by Targeting VISA. Journal of immunology, 2016, 197(12):4704-4713. (3) Lei Caoqi, Zhang Yu, Li Mi, Jiang Liqun, Zhong Bo, Kim Yonghao, Shu Hongbing*, ECSIT bridges RIG-I-like receptors to VISA in signaling events of innate antiviral responses. Journal of innate immunity, 2015, 7(2):153-164. (4) Lei Caoqi, Zhang Yu, Xia Tian, Jiang Liqun, Zhong Bo, Shu Hongbing*, FoxO1 negatively regulates cellular antiviral response by promoting degradation of IRF3. The Journal of biological chemistry, 2013, 288(18):12596-12604. (5) Lei Caoqi, Zhong Bo, Zhang Yu, Zhang Jing, Wang Shuai, Shu Hongbing*， Glycogen synthase kinase 3beta regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1. Immunity, 2010, 33(6):878-889. (1) Ye Wen, Hu Ming, Lei Caoqi, Zhou Qian, Lin Hen, Sun Mingshun, Shu Hongbing*, TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction. Journal of immunology, 2017, 199(5):1856-1864. (2) Jiang Liqun, Xia Tian, Hu Yunhong, Sun Mingshun, Yan Shuang, Lei Caoqi, Shu Hongbing, Guo Jihua, Liu Yu*, IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3. Cellular & molecular immunology, 2017. (3) Li Shun, Zhu Mingzhu, Pan Ruangang, Fang Ting, Cao Yuanyuan, Chen Shuliang, Zhao Xiaolu, Lei Caoqi，Guo Lin, Chen Yu, Li Chunmei, Eija Jokitalo, Yin Yuxin, Shu Hongbing, Guo Deying*, The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nature immunology, 2016, 17(3):241-249. (4) Li Dan, Yang Wenping, Yang Fan, Liu Huanan, Zhu Zixiang, Lian Kaiqi, Lei Caoqi, Li Shu, Liu Xiangtao, Zheng Haixue*, Shu Hongbing*, The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-beta signaling pathway. FASEB journal, 2016, 30(5):1757-1766. (5) Li Dan, Lei Caoqi, Xu Zhisheng, Yang Fan, Liu Huanan, Zhu Zixiaong, Li Shu, Liu Xiangtao, Shu Hongbing*, Zheng Haixue*, Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-beta signaling pathway. Scientific reports, 2016, 6:21888. (6) Hu Yunhong, Zhang Yu, Jiang Liqiong, Wang Shuai, Lei Caoqi, Sun Mingshun, Shu Hongbing, Liu Yu*, WDFY1 mediates TLR3/4 signaling by recruiting TRIF. EMBO report, 2015, 16(4):447-55. (7) Zhang Yu, Lei Caoqi, Hu Yunhong, Xia Tian, Li Mi, Zhong Bo, Shu Hongbing*, Kruppel-like factor 6 is a co-activator of NF-kappaB that mediates p65-dependent transcription of selected downstream genes. The Journal of biological chemistry, 2014, 289(18):12876-12885. (8) Liu Zhigang, Wu Shuwen, Lei Caoqi, Zhou Qian, Li Shu, Shu Hongbing, Wang Yanyi*, Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates. Protein & cell, 2013, 4(5):373-382. (9) Zhong Bo, Zhang Lu, Lei Caoqi, Li Ying, Mao Aiping, Yang Yan, Wang Yanyi, Zhang Xiaolian, Shu Hongbing*, The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity, 2009, 30(3):397-407. (10) Zhong Bo, Yang Yan, Li Shu, Wang Yanyi, Li Ying, Diao Feici, Lei Caoqi, He Xiao, Zhang Lu, Tien Po, Shu Hongbing*, The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity, 2008, 29(4):538-550.
