个人简历

学习简历： 2011/11-2012/05, University of Napoli Federico II, Napoli, Italy, Ph.D. student 2007/09-2012/06, 中科院上海药物研究所，天然药物化学研究室，博士 2001/09-2005/06, 中南大学，制药工程系，学士 工作简历： 2014/04-至今，武汉大学，药学院，讲师 2012/07-2014/03，武汉生物工程学院，制药工程系，讲师 2005/07-2007/09，浙江新和成股份有限公司、上海药明康德新药开发有限公司

研究领域

从事研究工作以来主要研究方向是药物化学，从药用植物、红树林植物、海洋动物（海绵，珊瑚等）及微生物中寻找结构新颖，活性显著的天然产物，并进行结构改造、修饰等工作，以期发现先导化合物。

近期论文

1) You-Sheng Cai, Yue-Wei Guo*, Karsten Krohn, Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes. Nat. Prod. Rep., 2010, 27, 1840–1870. 2) You-Sheng Cai, Tibor Kurtán*, Ze-Hong Miao, Attila Mándi, István Komáromi, Hai-Li Liu, Jian Ding, and Yue-Wei Guo*. Palmarumycins BG1-BG7 and Preussomerin BG1: establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra.J. Org. Chem., 2011, 76, 1821–1830. 3) You-Sheng Cai, Li-Gong Yao, Antonio Di Pascale, Carlo Irace, Ernesto Mollo, Orazio Taglialatela-Scafati*, Yue-Wei Guo*. Polyoxygenated diterpenoids of the eunicellin-type from the chinese soft coral Cladiella krempfi. Tetrahedron, 2013, 69, 2214–2219. 4) Lin-Fu Liang, Ting Wang, You-Sheng Cai(共同第一作者), Wen-Fei He, Peng Sun, Yu-Fen Li, Qi Huang, Orazio Taglialatela-Scafati*, He-Yao Wang*, Yue-Wei Guo*, Brominated polyunsaturated lipids from the Chinese sponge Xestospongia testudinaria as a new class of pancreatic lipase inhibitors. Eur. J. Med. Chem. 2014, 79, 290–297. 5) You-Sheng Cai, Hai-Li Liu, Jing-Xu Gong, Yue-Wei Guo*. Chemical constituents of mangrove plant Bruguiera gymnorrhiza. Chin. J. Mar. Drugs, 2011, 30, 15–18.